HOMEOKINETIC CLASSIFICATION OF MENOPAUSAL SYNDROME TAKING INTO ACCOUNT THE «VEGETATIVE PASSPORT» AND THE FORM OF COMORBIDITY

Authors

DOI:

https://doi.org/10.11603/24116-4944.2025.2.15795

Keywords:

menopausal syndrome, homeokinetic classification, «vegetative passport», comorbidity, sympathotonia, vagotonia, rehabilitation

Abstract

The aim of the study – development and discussion of the homeokinetic/pathogenetic classification of menopausal syndrome (MPS) taking into account the «vegetative passport», impaired homeokinesis parameters, and the form of comorbidity.

Materials and Methods. The basic results for the MPS classification were obtained at the clinical departments of DNMU and at the Medical Rehabilitation Center «Drive-Medical» (n=65). 47 practically healthy people formed the control group. Patients with MPS were divided into two groups according to heart rate variability (HRV) spectral analysis data and automated determination of the «vegetative passport». The form of comorbidity was established by the level of intracellular calcium in the hair (MAB-diagnosis). Computer electrocardiographs «ANS-Pro» and «Cardiolab-2000» were used. Statistical processing was carried out using ANOVA/MANOVA, correlation and regression analysis.

Results and Discussion. The conducted studies allowed us to formulate vagotonic and sympathotonic homeokinesis, the form of MPS and comorbidity. Sympathotonics are prone to calcium-excessive comorbidity (atherosclerosis), oxidative damage, dominance of catabolic hormones, acidosis, which forms MPS with relative estrogen deficiency. Vagotonics are prone to calcium-deficient comorbidity (osteoporosis), autoimmune aggression, dominance of anabolic hormones, alkalosis, which forms MPS with absolute estrogen deficiency. The proposed homeokinetic classification takes into account the «vegetative passport», the form of comorbidity, and the impairment of homeokinesis parameters.

Conclusions. Taking into account the homeokinetic classification of MPS, clinical tests for determining the «vegetative passport», the form of somatogenia, and typical clinical syndromes have been developed, which allows for compiling a rehabilitation diagnosis and predicting rehabilitation tactics.

Author Biographies

O. P. Sokrut, Donetsk National Medical University

Head of the Department of Rehabilitation and Sports Medicine

I. R. Mysula, I. Horbachevsky Ternopil National Medical University

Head of the Department of Medical Rehabilitation

V. M. Sokrut, Donetsk National Medical University

Head of the Department of Rehabilitation and Sports Medicine

M. V. Sokrut, Donetsk National Medical University

Associate Professor of the Department of Rehabilitation and Sports Medicine

A. G. Mullakhmetov, MRC «Drive-Medical», Kropyvnytskyi

Assistant of the Department of Orthopedics, Traumatology and Field Surgery

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Published

2025-12-15

How to Cite

Lytvynova, O. V., Sokrut, O. P., Mysula, I. R., Sokrut, V. M., Sokrut, M. V., & Mullakhmetov, A. G. (2025). HOMEOKINETIC CLASSIFICATION OF MENOPAUSAL SYNDROME TAKING INTO ACCOUNT THE «VEGETATIVE PASSPORT» AND THE FORM OF COMORBIDITY. Actual Problems of Pediatrics, Obstetrics and Gynecology, (2), 32–39. https://doi.org/10.11603/24116-4944.2025.2.15795

Issue

Section

OBSTETRICS AND GYNECOLOGY