FEATURES OF THE CLINICAL COURSE OF RECURRENT ACUTE RESPIRATORY DISEASES ON THE BACKGROUND OF LYMPHADENOID HYPERTROPHIA IN PRESCHOOL CHILDREN

Authors

DOI:

https://doi.org/10.11603/24116-4944.2024.1.14758

Keywords:

children, recurrent respiratory diseases, lymphadenoid hypertrophy, clinics, diagnosis, rhinosinusitis, cough, hyperthermia

Abstract

The aim of the study - to study the features of the clinical course of Recurent Respiratory Diseases (RRD) depending on the presence or absence of Concomitant Lymphadenoid Hypertrophy (CLH) in preschool children.

Materials and Methods. The subjects of the study were children aged 3–6 years with repeated episodes (6 or more within a year) of RRD in the anamnesis, who sought medical help for another episode of respiratory disease. The children were divided into 2 groups of 30 children each, depending on the presence of CLH. 20 physically healthy children who had less than 6 episodes of acute respiratory distress syndrome in the past year were included in the control group. The frequency and duration of episodes of acute respiratory disease during the last 12 months were studied retrospectively based on the analysis of medical records with the determination of the resistance index; the nosological spectrum of previous lesions of the respiratory tract, the development and characteristics of complications were analyzed. Regarding the current episode, the duration and severity of the main symptoms of acute respiratory disease, the volume of applied symptomatic and antibacterial therapy were evaluated in all children.

Results and Discussion. It was established that young children with RRD and background CLH had a greater average number and duration of respiratory episodes and a decrease in the resistance index. Among the nosological forms, post-viral rhinosinusitis and acute bronchitis prevailed in such children, and pneumonia was diagnosed probably more often than in children of the control group. At the same time, bacterial complications requiring antibiotic therapy were more often observed in children with CLH. The analysis of the main symptoms of acute respiratory syndrome showed that their duration and severity in children with CLH was probably greater compared to the control group, and such symptoms as the duration of cough and difficulty in nasal breathing bothered the children of this group significantly longer compared to children without concomitant lymphadenoid hypertrophy.

Conclusions. Lymphadenoid hypertrophy has an adverse effect on the health of preschool children, contributes to more frequent recurrence of respiratory pathology, increases the severity and duration of the main symptoms of the disease.

Author Biographies

О. B. Synoverska, Ivano-Frankivsk National Medical University

Doctor of Medical Sciences, Professor, Head of the Department of Children's Diseases

Kh. О. Lazurkevych, Ivano-Frankivsk National Medical University

candidate for the degree of Doctor of Philosophy, assistant of the Department of Children's Diseases

References

Berezhnyi, V.V. (2019). Hostri respiratorni zakhvoriuvannia u ditei: rannii startovyi pidkhid do terapii. Dokazova baza danykh (ohliad) [Acute Respiratory Infections in Children: an Early Startup Approach to Therapy. Evidence Database (review)]. Suchasna pediatriia - Modern pediatrics, 1(97), 89 - 100. DOI: 10.15574/SP.2019.97.89. [in Ukrainian]. DOI: https://doi.org/10.15574/SP.2019.97.89

Kryvopustov, S. P., Abaturov, O. Ye(2020). Hostri respiratorni infektsii v ditei [Acute Respiratory Infections in Children]. Zdorov’ia Ukrainy 21 storichchia - Health of Ukraine of the 21st century, 6 (475), 39. Retrieved from: https://repo.dma.dp.ua/id/eprint/ 5417. [in Ukrainian].

Lemko, O. I., Lukashchuk, S. V. (2019) Rekurentni respiratorni zakhvoriuvannia u praktytsi simeinoho likaria ta pediatra: osnovni pytannia (ohliad literatury )[Recurrent respiratory diseases in the practice of family doctors and pediatricians: main issues (literature review)]. Zaporizhskyi medychnyi zhurnal - Zaporizhia Medical Journal, 69(117), 835-842. DOI:10.14739/2310-1210.2019.6.186715 [in Ukrainian]. DOI: https://doi.org/10.14739/2310-1210.2019.6.186715

Markov, I.S., Markov, A. I. (2021) Klinichnyi obraz dytyny, shcho chasto khvoriie (novyi pohliad na pokhodzhennia, diahnostyku, likuvannia) Povidomlennia 1. Pokhodzhennia, klinika [Clinical picture in a child who often gets sick (a new look at the origin, diagnosis and treatment). Report 2. Diagnosis and treatment]. Aktualna infektolohiia - Actual infectology, 9(4), 28-42. DOI: https://doi.org /10.22141/2312-431Х.9.4.2021.246481. [in Ukrainian].

Synoverska, O. B., Berezna, T.H., Vovk, Z. V., Lazurkevych, Kh. O., Yakubiv-Han, I. H. (2021) Rekurentni zakhvoriuvannia v ditei: novi mozhlyvosti profilaktyky Zhurnal [Recurrent respiratory diseases in children: new opportunities for prevention]. Zdorov’ia dytyny - Child's health, (15)4, 21-20. Retrieved from: http://www.mif-ua.com/m/archive/article/49949. [in Ukrainian].

Chiappini, E., Santamaria, F., Marseglia, G.L., Marchisio, P., Galli, L. … Villani A. (2021). Prevention of recurrent respiratory infections: Inter-society Consensus. Ital J Pediatr. 47(1), 211. DOI: 10.1186/s13052-021-01150-0. DOI: https://doi.org/10.1186/s13052-021-01150-0

Chernyshova, L.I. (2018) Rekurentni respiratorni zakhvoriuvannia u ditei: alhorytm dii likaria (lektsiia) [Recurrent respiratory diseases in children: the physician's action algorithm (lecture)]. Suchasna pediatriia – Modern pediatrics, 3 (91), 92-97 DOI: 10.15574/SP.2018.91.92. [in Ukrainian]. DOI: https://doi.org/10.15574/SP.2018.91.92

Tsvirenko, S. M, Artiomova, N.S., Ananevych, O.I., Adruschenko, I. I., Bеlan, O.V. (2019) Osoblyvosti proiaviv hostrykh respiratornykh zakhvoriuvan u ditei rannoho viku. Aktualni problemy suchasnoi medytsyny [The manifestation features of acute respiratory diseases in infants]. Visnyk Ukrainskoi medychnoi stomatolohichnoi akademii -Bulletin of the Ukrainian Medical and Stomatological Academy, 19(4), 38-42. DOI: 10.31718/ 2077-1096.19.4.38. [in Ukrainian]. DOI: https://doi.org/10.31718/2077-1096.19.4.38

Corsello A., Milani G.P., Picca M., Buzzetti R., Carrozzo R., Gambino M., Chiaffoni G., Marchisio P., Mameli C. (2024) Recurrent upper respiratory tract infections in early childhood: a newly defined clinical condition. Ital J Pediatr. 2024, 16;50(1),30. DOI: 10.1186/s13052-024-01600-5. DOI: https://doi.org/10.1186/s13052-024-01600-5

Niedzielski, A., Chmielik, L.P., Mielnik-Niedzielska, G., Kasprzyk, A., Bogusławska J. (2023) Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance. BMJ Paediatrics Open, 7, e001710. DOI: 10.1136/ bmjpo-2022-001710. DOI: https://doi.org/10.1136/bmjpo-2022-001710

Zhang, X., Dai, X., Li, X., Xie, X., Chen, Y., Chen, Y., Guan, H. and Zhao Y. (2024) Recurrent respiratory tract infections in children might be associated with vitamin A status: a casecontrol study. Front. Pediatr., 11, 1165037. DOI: 10.3389/fped.2023.1165037. DOI: https://doi.org/10.3389/fped.2023.1165037

Ahmad, Z., Krüger, K., Lautermann, J., Lipper, В.T., Tenenbaum, Т., Tigges, М., Tisch, М. (2023). Adenoid hypertrophy—diagnosis and treatment: the new S2k guideline. HNO, 71 (Suppl 1), 67–72. DOI: 10.1007/s00106-023-01299-6. DOI: https://doi.org/10.1007/s00106-023-01299-6

Zwierz, A., Domagalski, K., Masna K., Burduk P. (2022) Effectiveness of evaluation of adenoid hypertrophy in children by flexible nasopharyngoscopy examination (FNE), proposed schema of frequency of examination: cohort study. Diagnostics, 12, 1734. DOI: 10.3390/ diagnostics12071734. DOI: https://doi.org/10.3390/diagnostics12071734

Xie, L., Gelfand, A., Murphy C.C. (2022) Prevalence of polypharmacy and associated adverse outcomes and risk factors among children with asthma in the USA: a cross-sectional. BMJ Open, 13, 12(10), e064708. DOI: 10.1136/bmjopen-2022-064708. DOI: https://doi.org/10.1136/bmjopen-2022-064708

Published

2024-04-15

How to Cite

Synoverska О. B., & Lazurkevych K. О. (2024). FEATURES OF THE CLINICAL COURSE OF RECURRENT ACUTE RESPIRATORY DISEASES ON THE BACKGROUND OF LYMPHADENOID HYPERTROPHIA IN PRESCHOOL CHILDREN. Actual Problems of Pediatrics, Obstetrics and Gynecology, (1), 101–106. https://doi.org/10.11603/24116-4944.2024.1.14758

Issue

Section

PEDIATRICS