A CLINICAL CASE REPORT OF MONDOR'S DISEASE OF THE BREAST
DOI:
https://doi.org/10.11603/24116-4944.2024.1.14754Keywords:
breast, acute thrombophlebitis, diagnosis, breast cancerAbstract
The aim of the study – to describe a rare clinical case of Mondor's disease of the breast, whose clinical symptoms can mimic breast cancer, and to analyze the diagnostic value of different imaging methods in this case.
Materials and Methods. A rare clinical case of Mondor's disease of the breast is described, a clinical examination of the patient was performed with the appointment of the necessary diagnostic methods, patient was treated according to current clinical protocols, and dynamic observation was performed. Assessment of the state of the mammary glands was carried out according to the standardized scale for evaluating the results of mammography, ultrasound and MRI according to the degree of risk of the occurrence of malignant neoplasms of the mammary glands BI-RADS (Breast Imaging-Reporting and Data System). Materials from the scientific databases PubMed, Google Scholar, Web of Science, and Scopus were processed to search for up-to-date information on methods of diagnosing pathology and approaches to treatment.
Results and Discussion. Mondor's disease is a rare pathology of the breast gland, manifested by acute thrombophlebitis of the superficial veins of the front and lateral walls of the chest and epigastrium, in particular, its symptoms can be manifested on the breasts. The report describes a clinical case of Mondor's disease of the left breast in a 40-year-old woman, which occurred after an acute respiratory infection. Clinical symptoms simulated breast cancer. The significance of various diagnostic methods is shown. Mammography turned out to be uninformative in this case. Ultrasound made it possible to visualize the thrombosed superficial vein of the breast. There were no changes in laboratory tests. Conservative treatment (general and local anti-inflammatory) proved to be effective.
Conclusions. Mondor's disease of the breast has a benign course and a favorable prognosis. A number of common symptoms with breast cancer require careful examination of the patient according to current protocols. Ultrasound with doppler is a more informative diagnostic method for this pathology than mammography. Awareness of the possibility of the occurrence of such a rare pathology can prevent the performance of unnecessary biopsy procedures in this case. Given the small frequency of pathology, each described case is interesting for study.
References
Shchepotin, I.B., Zotov, O.S., Zaivelieva, Iu.I., & Bezugla M.V.( 2012). Mondor’s disease: review and own experience. Klinichna onkolohiya, 6(2).
Ben Hamida, K., Ghalleb, M., Triki, A., Jebir, I., Makhlouf, R., & Touinsi, H. (2021). Mondor's disease of the breast: a case series. J Med Case Rep., 15(1), 188. DOI: 10.1186/s13256-021-02708-6. PMID: 33810810; PMCID: PMC8019160. DOI: https://doi.org/10.1186/s13256-021-02708-6
Obradovic, K., Adzic, N., Pavlovic Stankovic, D., Petkovic, I., Urban, V., & Milosevic, Z. (2020). Superficial thrombophlebitis of the breast (Mondor's disease): an uncommon localization of common disease. Clin Med Insights Case Rep., 13, 1179547620972414. DOI: 10.1177/1179547620972414. DOI: https://doi.org/10.1177/1179547620972414
Renshaw, L., Dixon, J.M., Anderson, J., & Turnbull, A.K. (2022). Mondor's disease of the breast: A cutaneous thromboembolic manifestation of Covid-19? Breast., 66, 305-309. DOI: 10.1016/j.breast.2022.11.006. Epub 2022 Nov 17. PMID: 36427369; PMCID: PMC9671393. DOI: https://doi.org/10.1016/j.breast.2022.11.006
Goldman, A. & Wollina, U. (2018) Mondor's Disease after aesthetic breast surgery: a case series and literature review. J Cutan Aesthet Surg., 11(3), 132-135. DOI: 10.4103/JCAS.JCAS_69_18. PMID: 30533987; PMCID: PMC6243822. DOI: https://doi.org/10.4103/JCAS.JCAS_69_18
Toshiyuki Yamaguchi. (2022). Mondor disease of the breast. Cleveland Clinic Journal of Medicine., 89(7), 371-372. DOI: 10.3949/ccjm.89a.21097. PMID: 35777840. DOI: https://doi.org/10.3949/ccjm.89a.21097
Vijayan, P. & Pang, F.T. (2023). Mondor’s disease of the breast in Asia: a forgotten diagnosis for the front-line clinicians – a case report and literature review. Egypt J Radiol Nucl Med., 54, 70 DOI: 10.1186/s43055-023-01020-1 DOI: https://doi.org/10.1186/s43055-023-01020-1
Pipal, D.K. & Pipal, V.R. (2022) Mondor's disease: a rare cause of chest pain. Cureus., 14(2), e22320. DOI: 10.7759/cureus.22320. PMID: 35317031; PMCID: PMC8934013. DOI: https://doi.org/10.7759/cureus.22320
Seemann, L.L., Ardon, T., Bowie, R.A., Bullock, K.C., & Clapp, A.D.M. (2024). Breast pain differential: Mondor’s disease of the breast. Journal of Investigative Medicine High Impact Case Reports., 12. DOI:10.1177/23247096241246621 DOI: https://doi.org/10.1177/23247096241246621
Yordanov, Y.P. (2019). Trauma on a recently augmented breast as a trigger for Mondor's disease. Aesthetic Plast Surg., 43(4), 927-929. DOI: 10.1007/s00266-019-01331-7. DOI: https://doi.org/10.1007/s00266-019-01331-7
Zeidan M. Mondor disease - breast. Case study.(2024). Radiopaedia.org. DOI: 10.53347/rID-98448 DOI: https://doi.org/10.53347/rID-98448
Rountree, K.M., Barazi, H., & Aulick, NF. (2024) Mondor disease. Treasure Island (FL): StatPearls Publishing. PMID: 30855866.
Wong, S.N., Lai, L.K., Chan, P.F., & Chao, D.V. (2017). Mondor's disease: sclerosing thrombophlebitis of subcutaneous veins in a patient with occult carcinoma of the breast. Hong Kong Med J., 23(3), 311-2. DOI: 10.12809/hkmj154699. DOI: https://doi.org/10.12809/hkmj154699
Shabani, Z. & Pllumi Guli, A. (2024) Case report of Mondor disease in a 49-year-old Albanian woman. Int J Surg Case Rep., 117, 109493. DOI: 10.1016/j.ijscr.2024.109493. Epub 2024 Mar 15. PMID: 38493614; PMCID: PMC10958058. DOI: https://doi.org/10.1016/j.ijscr.2024.109493
Hemsing, A.L. & Reikvam H. (2019) Mondor's disease after extensive training with Nordic walking. Oxf Med Case Reports., 2019(8), omz075. DOI: 10.1093/omcr/omz075. PMID: 31772743; PMCID: PMC6735834. DOI: https://doi.org/10.1093/omcr/omz075
Bastos Mendes, J.M., Ferreira Gomes, J.F., Rovisco Branquinho, L., Oliveira Carvalho, C., Pacheco Mendes, P.F.A.P., & Carvalho Madaleno, J.L. (2020) Mondor's disease: a rare cause of chest pain. Eur J Case Rep Intern Med., 7(12), 001984. DOI: 10.12890/2020_001984. PMID: 33457356; PMCID: PMC7806296. DOI: https://doi.org/10.12890/2020_001984
Suganthan, N., Ratnasamy, V. (2018) Mondor's disease - a rare cause of chest pain: a case report. J Med Case Rep., 12(1), 4. DOI: 10.1186/s13256-017-1530-x. PMID: 29310702; PMCID: PMC5759365. DOI: https://doi.org/10.1186/s13256-017-1530-x
Salemis, N.S., Vasilara, G.,& Lagoudianakis, E. (2015) Mondor's disease of the breast as a complication of ultrasound-guided core needle biopsy: management and review of the literature. Breast Dis., 35(1), 73-6. DOI: 10.3233/BD-140374. PMID: 24989360. DOI: https://doi.org/10.3233/BD-140374
de Almeida, M.J, Guillaumon, A.T., Miquelin, D., Joviliano, E.E., Hafner, L., Sobreira M.L., Geiger, M.A., Moura, R., Raymundo, S.,& Yoshida, W.B. (2019) Guidelines for superficial venous thrombosis. J Vasc Bras., 18, e20180105. DOI: 10.1590/1677-5449.180105. PMID: 31807127; PMCID: PMC6880617. DOI: https://doi.org/10.1590/1677-5449.180105
Faenza, M., Pelella, T., Antonetti, AM., Izzo, S., Grella, R.,& Ferraro, G.A. (2022) Mondor's disease as a complication in breast surgery in a male patient. The first ever reported case in literature. Case Reports Plast Surg Hand Surg., 9(1), 203-206. DOI: 10.1080/23320885.2022.2121711. PMID: 36147888; PMCID: PMC9487918. DOI: https://doi.org/10.1080/23320885.2022.2121711
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Actual Problems of Pediatrics, Obstetrics and Gynecology

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in this journal agree to the following terms:
1. The authors reserve the right to authorship of the work and pass the journal right of first publication of this work is licensed under a Creative Commons Attribution License, which allows others to freely distribute the work published with reference to the authors of the original work and the first publication of this magazine.
2. Authors are entitled to enter into a separate agreement on additional non-exclusive distribution of work in the form in which it was published in the magazine (eg work place in the electronic repository institution or publish monographs in part), provided that the reference to the first publication of this magazine.
3. Policy magazine allows and encourages authors placement on the Internet (eg, in storage facilities or on personal websites) manuscript of how to submit the manuscript to the editor and during his editorial processing, since it contributes to productive scientific discussion and positive impact on the efficiency and dynamics of citing published work (see. The Effect of Open Access).