CHARACTERISTICS OF REPRODUCTIVE FUNCTION IN WOMEN WITH FERTILITY AS A CONSEQUENCE OF "LONG-COVID"
DOI:
https://doi.org/10.11603/24116-4944.2023.2.13948Keywords:
reproductive health, COVID19, infertility, SARS-CoV-2, ART, psychoemotional statusAbstract
The aim of the study – to study the impact of "long-Covid" on the success of programs of assisted reproductive technologies in women with infertility.
Materials and Methods. To determine the possible impact of COVID-19 on women's reproductive health, we included 60 patients after COVID-19 in a comprehensive examination. The diagnosis of "long-COVID" was made in the presence of symptoms that were observed more than 12 weeks after the illness and were not associated with another pathology. The obtained data were processed by the methods of variational statistics accepted in medicine, using Fisher's angular transformation (to compare groups of patients according to indicators represented by frequencies in percentages in the group) with a critical level of significance > 0.05. The Microsoft Excel statistical analysis package was used.
Results and Discussion. Analysis of the distribution of patients with "long-COVID" by age did not reveal significant differences in groups depending on the success of DRT programs. At the same time, significant differences in the frequency of the main symptoms of "long-COVID" were established.Symptoms with a significant odds ratio should be highlighted in particular: "depression, anxiety." A significant difference between patients of subgroups 1 and 2 was also found in terms of social and household factors.Summarizing the above, we can say that among patients with infertility, a high frequency of "long-COVID" has been established, the consequences of which are various disorders of psychological, somatic, and reproductive health, which often arose precisely after suffering from the coronavirus disease.
Conclusions. Therefore, a significantly lower rate of success of DRT programs in female patients was established, which is due to the systemic impact of the coronavirus infection on the woman's body and reproductive function in particular. Risk factors for the ineffectiveness of ART programs have been established, among which stress, depression and anxiety, unhealthy lifestyle, metabolic disorders, liver pathology, menstrual cycle disorders, and urogenital infections are particularly prominent.
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