RETROSPECTIVE ANALYSIS OF CLINICAL FEATURES OF PATIENTS WITH ENDOMETRIOSIS-ASSOCIATED INFERTILITY WITH LONG AND SHORT OVULATION STIMULATION PROTOCOLS IN PROGRAMS OF ASSISTED REPRODUCTIVE TECHNOLOGIES

Authors

  • I. Ya. Pidhaina I. Horbachevsky Ternopil National Medical University Medical Center «Professor Stefan Khmil’s Clinic»
  • S. V. Khmil I. Horbachevsky Ternopil National Medical University Medical Center «Professor Stefan Khmil’s Clinic» https://orcid.org/0000-0003-0892-9861

DOI:

https://doi.org/10.11603/24116-4944.2022.2.13461

Keywords:

endometriosis, infertility, controlled ovarian stimulation, assisted reproductive technologies, endometrial polyps, endometrial hyperplasia, chronic endometritis, uterine fibroids, dyspareunia, algomenorrhea, cesarean section, body mass index, inflammatory diseases of female genital organs, ovary, endometrium

Abstract

The aim of the study – to analyze the clinical and anamnestic picture of patients with endometriosis-associated infertility in order to compare the effectiveness of ovulation stimulation protocols.

Materials and Methods. in accordance with the aim, general clinical data were retrospectively analyzed in 116 women with endometriosis-associated infertility with long and short ovulation stimulation protocols and a control group in assisted reproductive technology programs. The patients were divided into three groups. The first group consisted of 44 women with endometriosis-associated infertility who underwent controlled ovarian stimulation according to a long protocol with a-GnRH. The second group consisted of 42 patients with endometriosis-associated infertility, who underwent controlled ovarian stimulation according to a short protocol with anti-GnRH. The third comparison group (control) consisted of 30 women with tubal factor infertility.

Results and Discussion. a retrospective analysis of medical records, anamnestic data and general clinical indicators of women with endometriosis-associated infertility who underwent ovulation stimulation according to long and short protocols and control patients with tubal factor infertility was performed.

Conclusions: The obtained data indicate characteristic clinical and anamnestic differences in patients with endometriosis-associated infertility and tubal factor. The risk factors for infertility due to endometriosis include a history of surgical interventions, artificial abortions, pathological births, inflammatory diseases of the female genital organs, hormonal imbalance, changes in the immune system, environmental factors, and hereditary factors.

Author Biographies

I. Ya. Pidhaina, I. Horbachevsky Ternopil National Medical University Medical Center «Professor Stefan Khmil’s Clinic»

obstetrician-gynecologist of the medical center " Clinic of Professor S. Khmil"

S. V. Khmil, I. Horbachevsky Ternopil National Medical University Medical Center «Professor Stefan Khmil’s Clinic»

MD, PHD, DSc - Professor of the Department of Obstetrics and Gynecology No. 1 of Ternopil National Medical University named after I.Ya. Horbachevsky of the Ministry of Health of Ukraine, Doctor of Medical Sciences, Honored Worker of Science and Technology of Ukraine, General Director of the Medical Center " Clinic of Professor S. Khmil "

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Published

2022-12-15

How to Cite

Pidhaina, I. Y., & Khmil, S. V. (2022). RETROSPECTIVE ANALYSIS OF CLINICAL FEATURES OF PATIENTS WITH ENDOMETRIOSIS-ASSOCIATED INFERTILITY WITH LONG AND SHORT OVULATION STIMULATION PROTOCOLS IN PROGRAMS OF ASSISTED REPRODUCTIVE TECHNOLOGIES. Actual Problems of Pediatrics, Obstetrics and Gynecology, (2), 109–114. https://doi.org/10.11603/24116-4944.2022.2.13461

Issue

No. 2 (2022)

Section

OBSTETRICS AND GYNECOLOGY

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