DISRUPTION OF THE MENSTRUAL CYCLE ON THE BACKGROUND OF DISHORMONAL AND METABOLIC DISORDERS IN ADOLESCENTS DURING THE WAR

Authors

  • A. A. Synkina Sumy State University

DOI:

https://doi.org/10.11603/24116-4944.2022.2.13459

Keywords:

adolescent reproductive health, polycystic ovary syndrome, menarche, menstrual cycle disorders

Abstract

The aim of the study – to investigate the peculiarities of menstrual cycle disorders in teenagers against the background of excessive stress in order to develop a scientifically based set of measures for their correction.

Materials and Methods. 120 girls aged 9–18 who were in the war zone or became forced migrants were examined. Examination methods included anamnesis collection, assessment of psycho-emotional state, anthropometry, laboratory and instrumental studies.

Results and Discussion. In the conditions of military operations associated with long-term exposure to constant stress, the majority of teenagers have an increase in dyshormonal and metabolic disorders, which contributes to menstrual cycle disorders – 71.8 %, compared to peers – 19.2 %, the development of dysmenorrhea – 74.4 %, oligom enorrhea – 53.8 %, secondary amenorrhea – 28.2 % and excessive menstruation – 17.9 %. 71.7 % (n = 86) of the examinees noted a change in eating behavior over the past few months. Almost half of these children had dyshormonal disorders or met the criteria of metabolic syndrome – 45.3 % (n = 39).

Conclusions. Timely detection and adequate correction of psycho-emotional and metabolic disorders in adolescent girls in stressful conditions contributes to the prevention of disorders of menstrual and reproductive function.

Author Biography

A. A. Synkina, Sumy State University

graduate student of the Department of Obstetrics, Gynecology and Family Planning Sumy State University

References

Chaban, O.C., & Khaustova, O.O. (2022). Medyko-psykholohichni naslidky dystresu viyny v Ukrayini: shcho my ochikuyemo ta shcho potribno vrakhovuvaty pry nadanni medychnoyi dopomohy? [Medical and psychological consequences of war distress in Ukraine: what do we expect and what should be taken into account when providing medical aid?]. Aktualni pytannya medychnoyi praktyky. Ukrayinskyy medychnyy chasopys – Current Issues of Medical Practice. Ukrainian Medical Journal, 4(150), VII/VIII, 8-19 [in Ukrainian].

Chaban, O.S., & Frankova, I.A. (2019). Guilt, shame and social withdrawal in the context of post-traumatic stress disorder. Likarska sprava. Kyiv – Medical Case Kyiv, 1, 83-92. DOI: 10.31640/JVD.1-2.2019(12).

Kirschbaum, C., Kudielka, B.M., Gaab, J, Schommer, N.C., & Hellhammer, D.H. (1999). Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis. Psychosom. Med., 61(2), 154-162. DOI: 10.1097/00006842-199903000-00006.

Yehuda, R., Southwick, S.M., & Nussbaum, G. (1990). Low urinary cortisol excretion in patients with posttraumatic stress disorder. J. Nerv. Ment. Dis.,178, 366-369. DOI: 10.1097/00005053-199006000-00004.

Bouma, E.M., Riese, H., Ormel, J., Verhulst, F.C., & Oldehinkel, A.J. (2009). Adolescents' cortisol responses to awakening and social stress; effects of gender, menstrual phase and oral contraceptives, the trails study. Psychoneuroendocrinology, 34(6), 884-893. DOI: 10.1016/j.psyneuen.2009.01.003.

McFarlane, J., Symes, L., Binder, B.K., Maddoux, J., & Paulson, R. (2014). Maternal-child dyads of functioning: the intergenerational impact of violence against women on children. Matern. Child. Health. J., 18(9), 2236-2243. DOI: 10.1007/s10995-014-1473-4.

Daskalakis, N.P., Lehrner, A., & Yehuda, R. (2013). Endocrine aspects of post-traumatic stress disorder and implications for diagnosis and treatment. Endocrinol. Metab. Clin. North. Am., 42(3), 503-513. DOI: 10.1016/j.ecl.2013.05.004.

Kohut, A., Frankova, I., Potapov, O., Bobryk, M., Komisarenko, J., & Chaban, O. Multidisciplinary Intention: Revealing The Consequence of Psychosocial Factors on the Adherence to Treatment of the Patients with Type 2 Diabetes Mellitus. Mental Health Global Challenges Journal. DOI: 10.32437/MHGCJ-2019(1).

Bryant, R.A., Felmingham, K.L., Silove, D., Creamer, M., O'Donnell, M., & McFarlane, A.C. (2011). The association between menstrual cycle and traumatic memories. J. Affect. Disord., 131(1), 398-401. DOI: 10.1016/j.jad.2010.10.049.

Hillard, P.J. (2018). Puberty, menarche, and the menstrual cycle: what do we know, and what do we teach? J. Pediatr. Adolesc. Gynecol., 31, 331-332. DOI: 10.1016/j.jpag.2018.05.004.

Sheetal, B., Sheela, U., & Seeta, D. (2015). Influence of body mass index on menstrual irregularities in adolescent girls. Int. J. Med. Heal. Sci., 4, 213-216.

Hoppenbrouwers, K., Roelants, M., Meuleman, C., Rijkers, A., & Leeuwen, K., & Desoete, A. (2016). Characteristics of the menstrual cycle in 13-year-old Flemish girls and the impact of menstrual symptoms on social life. Eur. J. Pediatr., 175, 623-30. DOI: 10.1007/s00431-015-2681-7.

Tatarchuk, T.F., Kosey, N.V., & Regeda, S.I. (2019). The role of reproductive health disorders in the development of metabolic syndrome in women. Journal of the National Academy of Medical Sciences of Ukraine, 25(1), 77-87.

De Sanctis, V., Soliman, A.T., Elsedfy, H., Soliman, N.A., Elalaily, R., & El Kholy, M. (2016). Dysmenorrhea in adolescents and young adults: a review in different countries. Acta Biomed., 87, 233-246.

Gavela-Pérez, T., Navarro, P., Soriano-Guillén, L., & Garcés, C. (2016). High prepubertal leptin levels are associated with earlier menarcheal age. J. Adolesc. Heal., 59, 177-181. DOI: 10.1016/j.jadohealth.2016.03.042.

Tayebi, N., Yazdanpanahi, Z., Yektatalab, S., Pourahmad, S., & Akbarzadeh, M. (2018). The relationship between body mass index (BMI) and menstrual disorders at different ages of menarche and sex hormones. J. Natl. Med. Assoc., 110, 440-447. DOI: 10.1016/j.jnma.2017.10.007.

Padda, J., Khalid, K., & Hitawala, G. ( 2021). Depression and Its Effect on the Menstrual Cycle. Cureus, 13(7), e16532. DOI: 10.7759/cureus.16532.

Saboor Aftab, S.A., Kumar, S., & Barber, T.M. (2013). The role of obesity and type 2 diabetes mellitus in the development of male obesity-associated secondary hypogonadism. Clin. Endocrinol. (Oxf), 78(3), 330-337. DOI: 10.1111/cen.12092.

Desroches, S., & Lamarche, B. (2007). The evolving definitions and increasing prevalence of the metabolic syndrome. Appl. Physiol., Nutr. Metab, 32(1), 23-32. DOI: 10.1139/h06-095.

Agudelo, G.M., Bedoya, G., & Estrada, A. (2014). Variations in the prevalence of metabolic syndrome in adolescents according to different criteria used for diagnosis: which definition should be chosen for this age group? Metabolic Syndrome and Related Disorders, 12(4), 202-209. DOI: 10.1089/met.2013.0127.

Published

2022-12-15

How to Cite

Synkina, A. A. (2022). DISRUPTION OF THE MENSTRUAL CYCLE ON THE BACKGROUND OF DISHORMONAL AND METABOLIC DISORDERS IN ADOLESCENTS DURING THE WAR. Actual Problems of Pediatrics, Obstetrics and Gynecology, (2), 102–108. https://doi.org/10.11603/24116-4944.2022.2.13459

Issue

Section

OBSTETRICS AND GYNECOLOGY