STATE OF OVARIAN RESERVE UNDER THE CONDITIONS OF COMORBID PATHOLOGY OF THE MAMMARY GLANDS AND ENDOMETRIOSIS
DOI:
https://doi.org/10.11603/24116-4944.2022.2.13453Keywords:
endometriosis, laparoscopic method, oncomarker CA 125, ovarian reserve, mammary gland dysfunctionAbstract
The aim of the study – to determine the ovarian reserve and dynamics of CA-125 in patients with benign mammary gland pathology and endometriosis (EM) before surgical treatment.
Materials and Methods. 120 women aged 23 to 35 were included in the study. The control group consisted of 25 healthy non-pregnant women. All patients surveyed in the first stage was performed surgery.
Results and Discussion. Prevalence of autoimmune thyroiditis (38 %) is dominated by hypothyroidism (13 %) and hyperthyroidism (12 %).Dysmenorrhea bothered 36 % of patients, 19 % of patients complained of sleep disturbance, periodic headache – 24 %, feeling of fatigue – 29 %, hair loss – 18 %, dry skin – 12 %, swelling of the lower extremities – 18 %, weight gain – 42 %, transferred inflammatory diseases of the lower part of the genital tract in almost 43 % of patients, laparoscopic interventions for ovarian endometriosis in 68 %, myomectomy – in 9 %, primary infertility occurred in 72 % of women and secondary infertility – in 28 % of patients. Patients included in this study, the surveys were conducted, which included a thorough history, physical examination, staging process during laparoscopic interventions and determination of CA-125 and ovariane reserve.
Conclusions. Indicator of CA-125E and ovariane reserve are an effective marker of activity endometriosis process. We found that dyshormonal disorders of the mammary glands most often have accompanying dyshormonal pathology of the thyroid gland, endometriosis and infertility, which are associated with impaired reproductive function.
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