FEATURES OF THE CLINICAL COURSE OF PREGNANCY AND DELIVERY AS RISK FACTORS OF ANTENATAL DEATH OF THE FETAL IN PREGNANT WOMEN WITH DEFECTS OF FETAL DEVELOPMENT
DOI:
https://doi.org/10.11603/24116-4944.2022.2.13450Keywords:
congenital malformations, antenatal fetal death, risk factors, clinical course of pregnancy and childbirthAbstract
The aim of the study – to determine the risk factors of antenatal fetal death based on the characteristics of the course of pregnancy and childbirth in pregnant women with congenital malformations.
Materials and Methods. Clinical evaluation was performed in 100 pregnant women who gave birth to children with congenital malformations. The control group included 25 pregnant women who gave birth to healthy children during the same period of time. Statistical processing of the obtained results was carried out using the "Statistics 10" program. The relative risk of exposure to various factors was assessed by the odds ratio.
Results and Discussion. The results of the study of the frequency of congenital malformations showed that the main factors that can influence the formation of congenital malformations can be bad habits and occupational hazards, violations of menstrual function in the anamnesis, inflammatory diseases of the genital organs, involuntary abortions in the anamnesis. During pregnancy with congenital malformations of the fetus, frequent complications are the threat of abortion, early toxicosis, acute respiratory viral diseases in the early stages of pregnancy, extragenital diseases (diseases of the cardiovascular system and varicose veins). Childbirth in pregnant women with congenital malformations of the fetus proceeds prematurely, and proceeds with a large number of complications (premature rupture of the fetal membranes, anomalies of labor activity, fetal distress) and in 32.0±4.66 % of cases it ends operatively. Placental dysfunction was also observed in a third of pregnant women. The greatest risk of antenatal fetal death in congenital malformations of the fetus is the combination of congenital malformations with placental dysfunction. During a dopplerometric examination, disturbances are observed both in the uterine-placental and in the placental-fetal complex.
Conclusions. The use of factors of antenatal fetal death can contribute to the reduction of perinatal morbidity and mortality.
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