C-REACTIVE PROTEIN AS A BIOCHEMICAL CRITERION OF A GENERAL INFLAMMATORY SYNDROME IN LYME DISEASE IN CHILDREN

Authors

DOI:

https://doi.org/10.11603/24116-4944.2022.1.13251

Keywords:

Lyme disease, children, clinical symptom, C-reactive protein, inflammation

Abstract

The aim of the study – to improve the methods of non-specific biochemical markers of Lyme disease.

Materials and Methods. A group of children (62) aged from 1 to 14 years was observed for the identification of pathogens of blood-borne infections among children. C-reactive protein (CRP) is a protein and acute phase reagent as well as the information base for the interpretation and analysis of clinical observations of CRP.

 Results and Discussion. There were studied the concentrations of acute-phase response proteins including CRP in children with Lyme disease. We found that circulating of CRP levels as well as concentrations> 3 mg/ml was significantly higher in the group of children with Lyme arthritis cohort than in the control group (P <0.05).

Conclusions. C-reactive protein concentration is a very useful but non-specific biochemical marker of inflammation, the measurement of which makes an important contribution to the screening of Lyme borreliosis in children.

 

Author Biographies

S. O. Nykytyuk, I. Horbachevsky Ternopil National Medical University

MD, PhD, Associate Professor, I. Horbachevsky Ternopil National Medical University, Department of Children’s Diseases and Pediatric Surgery, Ukraine

S. I. Klumnyuk, I. Horbachevsky Ternopil National Medical University

професор, завідувач кафедри мікробіології, вірусології та імунології Тернопільського національного медичного університету ім. І.Я. Горбачевського

S. S. Levenets, I. Horbachevsky Ternopil National Medical University

PhD. Associate Professor, Department of Pediatrics with Surgery, I. Horbachevsky Ternopil National Medical University

T. О. Vorontsova, I. Horbachevsky Ternopil National Medical University

PhD. Associate Professor, Department of Pediatrics with Surgery, I. Horbachevsky Ternopil National Medical University

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Published

2022-10-19

How to Cite

Nykytyuk, S. O., Klumnyuk, S. I., Levenets, S. S., & Vorontsova T. О. (2022). C-REACTIVE PROTEIN AS A BIOCHEMICAL CRITERION OF A GENERAL INFLAMMATORY SYNDROME IN LYME DISEASE IN CHILDREN. Actual Problems of Pediatrics, Obstetrics and Gynecology, (1), 52–56. https://doi.org/10.11603/24116-4944.2022.1.13251

Issue

No. 1 (2022)

Section

PEDIATRICS

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