THE ROLE OF GENITAL INFECTIONS IN THE GENESIS OF VULVAR DISEASES
DOI:
https://doi.org/10.11603/24116-4944.2022.1.13218Keywords:
chronic vulvitis, genital candidiasis, vulvoscopyAbstract
The aim of the study – to examine the characteristics of vulvar diseases and their interrelation with genital infections.
Materials and Methods. It is necessary to examine patients with vulva diseases by vulvoscopy, find out different infections, measure local immunological status, and conduct biopsy regularly when there is a controversial result or atypical symbols during vulvoscopy. Medical treatment should include causal treatment according to sensitivity to antifungal, antimicrobial and antiviral drugs, and should activate the process of restoring the vulvar mucosa as well.
Results and Discussion. Dystrophic changes of the vulvar mucosa form a clinical diagnosis – chronic vulvitis or vulvar dysplasia. The main pathogen in the studied material Candida albicans was 81.6 %. 160 women had candidiasis and 95.9 % had chronic and long-term infection.
Conclusions. Considering the chronic nature of the inflammatory disease with various changes in the vulvar mucosa, medical treatment should last for a period of 1 to 6 months until the microorganisms are completely eradicated and atrophy of the vulvar mucosa is restored.
References
Burka, O.A., Tutchenko, T.M., & Pedachenko, N.Y. (2020). Modern approaches to the choice of antimicrobial agents for pelvic inflammatory diseases: the role of innovative microbiological methods. Reproductive Endocrinology, 1 (51), 25-31. DOI: 10.18370/2309-4117.2020.51.25-31
Borgdorff, H., Armstrong, S.D., & Tytgat, H.L. (2016). Unique insights in the cervicovaginal Lactobacillus iners and L. crispatus Proteomes and their associations with microbiota dysbiosis. PLoS ONE, 11, e0150767. DOI: 10.1371/ journal.pone.0150767
Borovikov, I.O., Kutsenko, I.I., & Rubinina, E.R. (2019). Preconceptional preparation of patients with mixed vaginal dysbiosis. RMJ. Mother and Child, 2 (2), DOI: 10.32364/2618-8430-2019-2-2-113-119
Demkin, V.V. (2018). Species diversity of lactobacilli of the vaginal microbiome: how to look. Molekulyarnaya genetika, mikrobiologiya i virusologiya – Molecular Genetics, Microbiology and Virusology, 36 (3), 3-12. DOI: 10.17116/ molgen2018360313
Curry, A., Williams, T., & Penny, M.L. (2019). Pelvic inflammatory disease: Diagnosis, management, and prevention. Am. Fam. Physician, 100, 357-364.
Dikke, G.B. (2019). Pelvic floor muscle insufficiency and violation of the vaginal microbiocenosis: results of complex treatment. Obstetrics and Gynecology, 4. DOI: 10.18565/aig.2019.4
Haggerty, C.L., Totten, P.A., & Tang, G. (2016). Identification of novel microbes associated with pelvic inflammatory disease and infertility. Sex Transm. Infect., 92, 441-446
Origoni, M. (2014). Cervical intraepithelial neoplasia (CIN) in pregnancy: the state of the art. European Review for Medical and Pharmacological Sciences, 18, 851-860.
Dunaevskaya, V.V., Tatarchuk, T.F., Zakharenko, N.F., Tserkovsky, & D.A., Solsky, V.S. (2020). Photodynamic therapy in the treatment of patients with precancerous diseases of the vulva. The first experience of applying the method in Ukraine. Reproductive Endocrinology, 54, 22-26.
Тatarchuk, T.F., Kalugina, L.V., Petrova, G.A., Radchenko, V.V., Shaverska, V.V., Sorokina, A.M., & Smirnova, O.V. (2020). Syndrome of vaginal discharge. The problem with many unknowns. Reproductive Endocrinology, 53, 94-100.
Sherrard, J., Wilson, J., & Donders, G. (2018). European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of vaginal discharge. International Journal of STD & AIDS, 29(13), 1258-1272.
Kalugina, L.V., Tatarchuk, T.F., & Shakalo, I.N. (2016). Nonspecific vulvovaginitis of mixed etiology: local treatment – the treatment of choice. Reproductive Endocrinology, 1 (27), 94-100. DOI: /10.18370/2309-4117.2016.27.94-100
Stewart, L.M., Stewart, C.J.R., & Spilsbury, K., et al. (2020). Association between pelvic inflammatory disease, infertility, ectopic pregnancy and the development of ovarian serous borderline tumor, mucinous borderline tumor and low-grade serous carcinoma. Gynecol Oncol. DOI:10.1016/j. ygyno.2020.01.027
Workowski, K.A., & Bolan, G.A. (2015). Sexually Transmitted Diseases Treatment Guidelines. MMWR Recomm. Rep., 64 (RR 03), 1–137.
Kuznetsova, I.V. (2019). Diagnosis and therapy of mixed and recurrent vulvovaginal infections. Medical Alphabet, 25 (3), 23-29.
Gusak, Y.K., Rischuk, S.V., & Tarasov, V.N. (2019). Infectious diseases of the vagina. Finding the best solution in their therapy. Defense or attack? Bulletin of new medical technologies. Electronic Resource, 4, 22-40.
Mason, M.J., & Winter, A.J. (2017). How to diagnose and treatbaerobic and desquamative inflammatory vaginitis. Sex Transm. Infect., 93, 8-10.
Neut, C., Verrière, F., Nelis, H.J., & Coenye, T. (2015). Topical treatment of infectious vaginitis: Effects of antibiotic, antifungal and antiseptic drugs on the growth of normal vaginal Lactobacillus strains. Open Journal of Obstetrics and Gynecology, 5, 173-180. DOI: 10.4236/ ojog.2015.53024
Iungin, O.S. (2018). Antifungal agents in the context of acquired resistance in fungi of the genus Candida. Bulletin of Biology and Medicine Problems, 2 (144), 83-86.
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