STATE OF THE REPRODUCTIVE SYSTEM IN LATE REPRODUCTIVE AGE IN WOMEN WITH SECONDARY INFERTILITY AFTER HYSTEROSCOPIC METROPLASTY
DOI:
https://doi.org/10.11603/24116-4944.2021.2.12762Keywords:
uterine septum, hysteroscopic metroplasty, miscarriage, repeated pregnancy loss, secondary infertilityAbstract
The aim of the study – to determine the risk of secondary infertility after hysteroscopic metroplasty due to the uterine septum.
Materials and Methods. We retrospectively analyzed 102 medical records of patients with uterine septum who underwent hysteroscopic metroplasty during 2018–2021. A retrospective, single-center, cohort study included women with a history of at least two miscarriages associated with uterine septal hysteroscopic metroplasty. Baseline data were compared between patients who became pregnant and those who became infertile 1 year after hysteroscopic metroplasty. Data were analyzed using the Mann – Whitney U test.
With the help of the licensed program SPSS v.21 statistical processing of data entered in spreadsheets Excel–2010. In parallel with the search engines Pubmed, Google Scholar, Sciencedirect, Webcardio conducted an analysis of literature sources on this topic for the past 5 years.
Results and Discussion. The incidence of pregnancies after surgical correction was 83.9 % (26/31), the total number of live births per operation was 80.6 % (25/31), and the total live birth rate per pregnancy was 96.2 % (25 / 26). Comparison of pregnant (26) and infertile (5) women after hysteroscopic metroplasty did not reveal a significant difference in the number of previous miscarriages, features of past infertility treatment, anatomical location of the intrauterine septum or the presence of residual postoperative septum.
Thus, despite the high efficiency of hysteroresectoscopy in women of late reproductive age with an intrauterine septum which results in pregnancy in 83.9 % of women and the birth of a living child in 80.6 %.
Conclusions. The negative impact of surgical treatment of the uterine septum in women of late reproductive age cannot be clearly stated, as high live birth rates persist.
In addition, these studies indicate that the use of hysteroscopic metroplasty does not correlate with the development of secondary infertility. Namely, late reproductive age may contribute to the development of these changes. Therefore, it is the provision of early surgery and sufficient volume that will help achieve the desired results for fertility.
References
Dankovich, N.A., & Vorobey-Vikhovskaya, V.N. (2013). Prichiny i formy besplodiya. Sovremennyye vozmozhnosti diagnostiki i lecheniya [Causes and forms of infertility. Modern possibilities of diagnosis and treatment]. Zdorovye zhenshchiny– Womenʼs Health, 3, 192-197 [in Russian].
Yuzko, O.M., Yuzko, T.A., & Rudenko, N.H. (2013). Stan ta perspektyvy vykorystannia dopomizhnykh reproduktyvnykh tekhnolohii pry likuvanni bezpliddia v Ukraini [Status and pros-pects of using assisted reproductive technologies in the treat-ment of infertility in Ukraine]. Zdorovye zhenshchiny – Womenʼs Health, 8, 26-30 [in Ukrainian].
Avramenko, N.V. (2014). Vspomogatelnyye reproduktivnyye tekhnologii [Assisted reproductive technologies]. Zaporozhskiy meditsinskiy zhurnal – Zaporozhye Medical Journal, 3 (84), 95-100 [in Russian].
Forouhari, S., & Ghaemi, S.Z. (2013). A survey of psychosexual disorders in infertile women referred to the Zeinabiee Infertility Center of Shiraz University of Medical Sciences. Res. J. Biol. Sci., 8 (4), 99-103. DOI: 10.36478/rjbsci.2013.99.103.
Monga, M., Alexandrescu, B., Katz, S.E., Stein, M., & Ganiats, T. (2004). Impact of infertility on quality of life, marital adjustment, and sexual function. Urology, 63 (1), 126-130. DOI: 10.1016/j.urology.2003.09.015.
Jun Chi, H., Park, I.H., Sun, H.G., Kim, J.W., & Lee, K.H. (2016). Psychological distress and fertility quality of life (FertiQoL) in infertile Korean women: The first validation study of Korean FertiQoL. Clin. Exp. Reprod. Med., 43 (3), 174-180. DOI: 10.5653/cerm.2016.43.3.174.
Keramat, A., Masoomi, S.Z., Mousavi, S.A., Poorolajal, J., Shobeiri, F., & Hazavhei, S.M. (2014). Quality of life and its re-lated factors in infertile couples. J. Res. Health Sci., 14 (1), 57-63.
Ramezanzadeh, F., Aghssa, M.M., Abedinia, N., Zayeri, F., Khanafshar, N., Shariat, M., & Jafarabadi, M. (2004). A survey of relationship between anxiety, depression and duration of infertility. BMC Womens Health, 4 (1), 9. DOI: 10.1186/1472-6874-4-9.
Ware, J.E., Snow, K.K., Kosinski, M., & Gandek, B. (1993). SF-36 Health Survey. Manual and interpretation guide. The Health Institute, New England Medical Center. Boston, Mass.
Boivin, J., Takefman, J., & Braverman, A. (2011). The fertility quality of life (FertiQoL) tool: development and general psychometric properties. Hum. Reprod., 26 (8), 2084-2091. DOI: 10.1093/humrep/der171.
Dakhno, F.V., & Kaminskyi, V.V. (Eds.). (2011). Dopomizhni reproduktyvni tekhnolohii likuvannia bezpliddia: navchalnyi posibnyk dlia likariv slukhachiv zaklfdiv pisliadyplomnoi osvity [Assisted reproductive infertility treatment technologies: A manual for doctors-listeners postgraduate education courses]. Kyiv [in Ukrainian].
Lee, A., Sator, M., Kratochwil, A., Deutinger, J., Vytiska-Binsdorfer, E., & Bernaschek, G. (1997). Endometrial volume change during spontaneous menstrual cycles: volumetry by transvaginal three-dimensional ultrasound. Fertil. Steril., 68, 831-835. DOI: 10.1016/s0015-0282(97)00362-2.
Raine-Fenning, N.J., Campbell, B.K., Clewes, J.S., Ken-dall, N.R., & Johnson, I.R. (2004). Defining endometrial growth during the menstrual cycle with three-dimensional ultrasound. BJOG, 111 (9), 944-949. DOI: 10.1111/j.1471-0528.2004.00214.x.
Palyga, I.E. (2013). Klinicheskiy analiz neudachnykh popy-tok ispolzovaniya vspomagatelnykh reproduktivnykh tekhnologiy [Clinical analysis of failed attempts to use assisted reproductive technologies]. Zdorovye zhenshchiny – Womanʼs Health, 8 (84), 164-166 [in Russian].
Baskakov, V.P. (2005). Sostoyanie reproduktivnoy sistemy zhenshchiny pri endometrioze [Condition of the reproductive system of a woman with endometriosis]. Problemy reproduktsii – Problems of Reproduction, 2, 15-18 [in Russian].
Babenko, I.V. (2013). Vykorystannia modyfikovanoho pryrodnoho tsyklu v dopomizhnykh reproduktyvnykh tekhnolo-hiiakh u patsientok z neplidnistiu i znyzhenym yaiechnykovym rezervom [Use of the modified natural cycle in assisted reproduc-tive technologies in patients with infertility and reduced ovarian reserve]. Zbirnyk naukovykh prats Asotsiatsii akusheriv-hinekolohiv Ukrainy – Collection of Scientific Works of the Association of Obstetricians-Gynecologists of Ukraine. (pp. 18-19). Kyiv: “Polihraf plius” [in Ukrainian].
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