THE FEATURES OF OBSTETRIC COMPLICATIONS DEVELOPMENT IN PREGNANT WOMEN WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASES (THE LITERATURE REVIEW AND OWN RESEARCH)
DOI:
https://doi.org/10.11603/24116-4944.2021.1.12368Keywords:
chronic obstructive pulmonary diseases, endothelial dysfunction, pregnancy complications, oxidative stress, acid-base balanceAbstract
The problem of chronic obstructive pulmonary diseases in pregnant women increasingly has become relevant in obstetrics. The body's oxygen needs increasing by 15–20 % during physiological pregnancy, and therefore, in the presence of chronic pathology, this can cause decompensation of the disease as well as change the clinical course of pregnancy. Thus, the combination of chronic obstructive pulmonary disease with pregnancy can cause unpredictable complications for both mother and fetus.
The aim of the study – to determine and analyze the factors that affecting occurrence on the obstetric complications in pregnant women with chronic obstructive pulmonary diseases.
Materials and Methods. Bibliosemantic and analytical methods were used in this literature review.
Results and Discussion. A connection between the severity of endothelial dysfunction, lipid peroxidation, and the activity of the antioxidant defense system in pregnant women with chronic obstructive pulmonary disease, was found. The chronic obstructive diseases are accompanied by the activation of free radical processes in the lungs. Free radicals have the ability to modify proteins, lipids, nucleic acids, which cause endothelial dysfunction. Endothelial dysfunction is currently considered one of the main pathogenetic mechanisms underlying the development of such obstetric complications as premature birth, placental dysfunction, intrauterine growth retardation, preeclampsia and others. A retrospective analysis of 120 histories of pregnant women with chronic obstructive pulmonary diseases revealed that the following obstetric complications had been developed: placental dysfunction in 65.0 %, premature birth in 55.8 %, preeclampsia in 38.3 %, intrauterine growth retardation in 16.6 %, premature ruptured membrane in 15 %, fetal distress in 12.5 %.
Conclusion. Chronic obstructive pulmonary diseases in pregnant women are accompanied with endothelial dysfunction, lipid peroxidation violation and increascent oxidative stress that need to develop an adequate programs for prediction of the obstetrics and perinatal complications in pregnant women with chronic obstructive pulmonary diseases.
References
(2017). Global Initiative for Chronic Obstructive Lung Disease (GOLD).
Blais, L., & Forget, A. (2008). Asthma exacerbations during the first trimester of pregnancy and the risk of congenital malformations among asthmatic women. J. Allergy Clin. Immunol., 121 (6), 1379-1384. DOI: 10.1016/j.jaci.2008.02.038.
Burney, P.G., Patel, J., Newson, R., Minelli, C., & Naghavi, M. (2015). Global and regional trends in COPD mortality, 1990–2010. Eur. Respir. J., 45 (5), 1239-1247. DOI: 10.1183/09031936.00142414.
Han, M.K., Postma, D., Mannino, D.M., Giardino, N.D., Buist, S., Curtis, J.L., & Martinez, F.J. (2007). Gender and chronic obstructive pulmonary disease: why it matters. Am. J. Respir. Crit. Care Med., 176 (12), 1179-1184. DOI: 10.1164/rccm.200704-553CC.
Vos, T., Flaxman, A.D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., …, & Memish, Z.A. (2012). Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380 (9859), 2163-2196. DOI: 10.1016/S0140-6736(12)61729-2.
Lamprecht, B., McBurnie, M.A., Vollmer, W.M., Gudmundsson, G., Welte, T., Nizankowska-Mogilnicka, E., …, & Buist, S.A. (2011). COPD in never smokers: results from the population-based burden of obstructive lung disease study. Chest, 139 (4), 752-763. DOI: 10.1378/chest.10-1253.
Khronichne obstruktyvne zakhvoriuvannia leheni. Adaptovana klinichna nastanova zasnovana na dokazakh (Zatverdzheno Nakazom Ministerstva okhorony zdorovia Ukrainy vid 16.04.2014 № 270 zi zminamy) [Chronic obstructive pulmonary disease. Adapted clinical guidelines based on evidence (approved by Order of the Ministry of Health of Ukraine dated April 16, 2014 No. 270 as amended)]. Retrieved from: https://www.dec.gov.ua/wp-content/uploads/2019/11/2013_555_hozl_kn.pdf [in Ukrainian].
Aryal, S., Diaz-Guzman, E., & Mannino, D.M. (2014). Influence of sex on chronic obstructive pulmonary disease risk and treatment outcomes. Int. J. Chron. Obstruct. Pulmon. Dis., 9, 1145-1154. DOI: 10.2147/COPD.S54476.
Sørheim, I.C., Johannessen, A., Gulsvik, A., Bakke, P.S., Silverman, E.K., & DeMeo, D.L. (2010). Gender differences in COPD: are women more susceptible to smoking effects than men? Thorax, 65 (6), 480-485. DOI: 10.1136/thx.2009.122002.
Ovcharenko, S.I., & Kapustina, V.A. (2009). Khronicheskaya obstruktivnaya bolezn legkikh: osobennosti u zhenshchin [Chronic obstructive pulmonary disease: particularities in women]. Pulmonologiya – Pulmonology, 2. DOI: https://doi.org/10.18093/0869-0189-2009-2-102-112 [in Russian].
Arkhipov, V.V. (2002). Zabolevaniya legkikh pri beremennosti [Lung diseases in pregnancy]. Chuchalin, A.G., Krasnopolskyy, V.I., & Fassakhov, R.S. (Eds.). Moscow: Atmosfera [in Russian].
Sukhovsky, V.S., Tetenev, F.F., & Sukhovskaya, V.V. (2012). Dinamicheskaya giperinflyatsiya legkikh v period gestatsii [Dynamic lung huperinflation in pregnancy]. Pulmonologiya – Pulmonology, 2, 25-29. DOI: https://doi.org/10.18093/0869-0189-2012-0-2-25-29.
Huang, X., Mu, X., Deng, L., Fu, A., Pu, E., Tang, T., & Kong, X. (2019). The etiologic origins for chronic obstructive pulmonary disease. Int. J. Chron. Obstruct. Pulmon. Dis., 14, 1139-1158. DOI: 10.2147/COPD.S203215.
Hirnle, L., Lysenko, L., Gerber, H., Lesnik, P., Baranowska, A., Rachwalik, M., …, & Strozecki, L. (2013). Respiratory function in pregnant women. Adv. Exp. Med. Biol., 788, 153-160. DOI: 10.1007/978-94-007-6627-3_23.
Gorikov, I.N., Nakhamchen, L.G., Kostoromina, N.O., & Sudakov, A.G. (2012). Vliyaniye obostreniya khronicheskogo neobstruktivnogo i obstruktivnogo bronkhita virusnoy etiologii u zhenshchin vo vtorom trimestre beremennosti na sostoyaniye tserebralnogo krovotoka u ikh novorozhdennykh [The Influence of the acute form of chronic non-obstructive and obstructive bronchitis of virus etiology in women in II trimester of pregnancy on the state of cerebral bloodflow in their newborns]. Byul. fiziologii i patologii dykhaniya – Bull. Physiology and Pathology of Respiration, 46, 48-51 [in Russian].
Lavrova, O.V., & Fedoseyeva, G.B. (2011). Vliyaniye techeniya beremennosti i rodov u zhenshchin, stradayushchikh bronkhialnoy astmoy, na formirovaniye etoy patologii. Mnogolikaya astma, diagnostika, lecheniye i profilaktika [The influence of the course of pregnancy and childbirth in women suffering from bronchial asthma on the formation of this pathology. The many faces of asthma, diagnosis, treatment and prevention]. Saint-Petersburg [in Russian].
Prikhodko, O.B., Romantsova, Ye.B., & Babtseva, A.F. (2007). Adaptatsionnyye reaktsii u beremennykh s khronicheskimi obstruktivnymi zabolevaniyami oragnov dykhaniya [Adaptive reactions in pregnant women with chronic obstructive diseases of respiratory organs]. Byul. fiziologii i patologii dykhaniya – Bull. Physiology and Pathology of Respiration, 24, 66-68 [in Russian].
Wise, R.A., Polito, A.J., & Krishnan, V. (2006). Respiratory physiologic changes in pregnancy. Immunol. Allergy Clin. North Am., 26 (1), 1-12. DOI: 10.1016/j.iac.2005.10.004.
Bafadhel, M., McKenna, S., Terry, S., Mistry, V., Reid, C., Haldar, P., …, & Brightling, C.E. (2011). Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am. J. Respir. Crit. Care Med., 184 (6), 662-671. DOI: 10.1164/rccm.201104-0597OC.
Aaron, S.D., Donaldson, G.C., Whitmore, G.A., Hurst, J.R., Ramsay, T., & Wedzicha, J.A. (2012). Time course and pattern of COPD exacerbation onset. Thorax, 67 (3), 238-243. DOI: 10.1136/thoraxjnl-2011-200768.
Avdeev, S.N. (2014). Znacheniye obostreniy dlya patsiyentov s KhOBL [Importance of relapses in COPD patients]. Effektivnaya farmakoterapiya – Effective Pharmacotherapy, 2 (29), 36-41 [in Russian].
Majori, M., Corradi, M., Caminati, A., Cacciani, G., Bertacco, S., & Pesci, A. (1999). Predominant TH1 cytokine pattern in peripheral blood from subjects with chronic obstructive pulmonary disease. J. Allergy Clin. Immunol., 103 (3 Pt 1), 458-462. DOI: 10.1016/s0091-6749(99)70471-9.
Borukayeva, I.Kh. (2007). Osobennosti respiratornoy gipoksii u bolnykh khronicheskoy obstruktivnoy boleznyu legkikh [Features of respiratory hypoxia in patients with chronic obstructive pulmonary disease]. Uspekhi sovremennogo yestestvoznaniya – Advances in Current Natural Sciences, 1, 54-56 [in Russian].
Gillet, S., Barbu, C.A., & Poncelet, M. (2011). Inflammation in COPD: pathogenesis, local and systemic effects. Rom. J. Morphol. Embryol., 52 (1), 21-27.
Nakhamchen, L.G., Gorikov, I.N., Prikhodko, V.B., & Kvitkina, I.G. (2015). Sostoyaniye fetoplatsentarnoy sistemy pri obostrenii khronicheskogo neobstruktivnogo i obstruktivnogo bronkhita u zhenshchin v tretyem trimestre beremennosti [The state of fetoplacental system at exacerbation of chronic nonobstructive and obstructive bronchitis in women in iii trimester of pregnancy]. Byul. fiziologii i patologii dykhaniya – Bull. Physiology and Pathology of Respiration, 55, 73-77 [in Russian].
Nakhamchen, L.G., Gorikov, I.N., & Talchenkova, T.Ye. (2012). Izmeneniya mestnoy spetsificheskoy zashchity tsitokinovogo statusa u zhenshchin v 1 trimestre beremennosti pri obostrenii khronicheskogo bronkhita obuslovlennogo virusami respiratornoy grup [Change of local specific protection and cytokine status in women in the first trimester of pregnancy at the acute form of chronic bronchitis conditioned by the viruses of respiratory group]. Byul. fiziologii i patologii dykhaniya – Bull. Physiology and Pathology of Respiration, 46, 44-47 [in Russian].
Belan, E.B., & Klyausov, A.S. (2014). Bronkhialnaya astma i beremennost [Bronchial asthma and pregnancy]. Lekarstvennyy vestnik – Drug Bulletin, 8, 1 (53), 8-17 [in Russian].
(2016). The Global Initiative for Asthma (GINA).
Murphy, V.E., Namazy, J.A., Powell, H., Schatz, M., Chambers, C., Attia, J., & Gibson, P.G. (2011). A meta-analysis of adverse perinatal outcomes in woman with asthma. BJOG, 118 (11), 1314-1323. DOI: 10.1111/j.1471-0528.2011.03055.x.
Maselli, D.J., Adams, S.G., Peters, J.I., & Levine, S.M. (2013). Management of asthma during pregnancy. Ther. Adv. Respir. Dis., 7 (2), 87-100. DOI: 10.1177/1753465812464287.
Rybalka, A.N., Rumyantseva, Z.S., Lyashenko, H.N., Dizha, M.A., Gurskij, A.V. (2015). Etiopatogeneticheskiye aspekty techeniya bronkhialnoy astmy vo vremya gestatsii [Etiopathogenical aspects of bronchial asthma during gestation]. Zhurnal fundamentalnoy meditsiny i biologii – J. Fund. Med. Biol., 3, 35-37 [in Russian].
Voronina, L.P., Polunina, O.S., Sevostyanova, I.V., Kudryasheva, I.A., Kagin, A.V., & Serdyukov, V.G. (2013). Vliyaniye oksidativnogo stressa na mikrososudistyy endoteliy pri bronkhialnoy astme [The influence of oxidative stress on endothelium of microvessels at bronchial asthma]. Astrakhanskiy meditsinskiy zhurnal – Astrakhan Medical Journal, 4, 8, 54-57 [in Russian].
Clifton, V.L., Vanderlelie, J., & Perkins, A.V. (2005). Increased anti-oxidant enzyme activity and biological oxidation in placentae of pregnancies complicated by maternal asthma. Placenta, 26 (10), 773-779. DOI: 10.1016/j.placenta.2004.10.018.
Scott, N.M., Hodyl, N.A., Murphy, V.E., Osei-Kumah, A., Wyper, H., Hodgson, D.M., …, & Clifton, V.L. (2009). Placental cytokine expression covaries with maternal asthma severity and fetal sex. J. Immunol., 182 (3), 1411-1420. DOI: 10.4049/jimmunol.182.3.1411.
Vereina, N.K., & Chulkov, V.S. (2010). Techeniye beremennosti i rodov sostoyaniye endoteliya u patsiyentok kurivshikh do beremennosti [The course of pregnancy and childbirth, the state of the endothelium in female patients who smoked before pregnancy]. Zhurnal akusherstva i zhenskikh bolezney – Journal of Obstetrics and Women's Diseases, LIX, 3, 110-113 [in Russian].
Ivanova, O.Yu., Gazazyan, M.G., & Ponomaryova, N.A. (2010). Sostoyaniye vazoreguliruyushchey funktsii endoteliya pri fiziologicheskom i oslozhnennom techenii beremennosti [Condition of vasoregulative function of endothelium in case of uncomplicated and complicated pregnancies]. Kurskiy nauch.-prakt. vest. «Chelovek i yego zdorovye» – Kursk Scientific and Practical Bulletin "Man and His Health", 4, 68-72 [in Russian].
Ahmineeva, A.H., & Polunina, O.S. (2012). Disfunktsiya endoteliya pri khronicheskoy obstruktivnoy bolezni legkikh i bronkhialnoy astme [The dysfunction of endothelium in chronic obstructive pulmonary disease and bronchial asthma]. Astrakhanskiy meditsinskiy zhurnal – Astrakhan Medical Journal, 3, 7, 43-46 [in Russian].
Furchgott, R., & Zawadzki, J. (1980). The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature, 288 (5789), 373-376. DOI: 10.1038/288373a0.
Dorofienko, N.N. (2018). Rol sosudistogo endoteliya v organizme i universalnyye mekhanizmy izmeneniya yego aktivnosti (obzor literatury) [The role of vascular endothelium in the organism and the universal mechanisms of changing its activity (review)]. Byul. fiziologii i patologii dykhaniya – Bull. Physiology and Pathology of Respiration, 68, 107-116 [in Russian].
Burton, G.J., & Jauniaux, E. (2011). Oxidative stress. Best Pract. Res. Clin. Obstet. Gynaecol., 25 (3), 287-299. DOI: 10.1016/j.bpobgyn.2010.10.016.
Wu, F., Tian, F.J., Lin, Y., & Xu, W.M. (2016). Oxidative stress: placenta function and dysfunction. Am. J. Reprod. Immunol., 76 (4), 258-271. DOI: 10.1111/aji.12454.
Sultana, Z., Maiti, K., Aitken, J., Morris, J., Dedman, L., & Smith, R. (2017). Oxidative stress, placental ageing-related pathologies and adverse pregnancy outcomes. Am. J. Reprod. Immunol., 77 (5). DOI: 10.1111/aji.12653.
Kurlak, L.O., Green, A., Loughna, P., & Broughton Pipkin, F. (2014). Oxidative stress markers in hypertensive states of pregnancy: preterm and term disease. Front. Physiol., 5, 310. DOI: 10.3389/fphys.2014.00310.
Zverko, V.L., Maksimovich, N.Ye., & Milosh, T.S. (2010). Nedostatochnoye obrazovaniye oksida azota kak odin iz patogeneticheskikh faktorov ugrozy nevynashivaniya beremennosti [Insufficient formation of nitrogen oxide as one of the pathogenetic factors of the threat of miscarriage]. Zhurnal Grodnenskogo gosudarstvennogo meditsinskogo universiteta – Journal of Grodno State Medical University, 3, 60-62 [in Russian].
Mamaeva, M.G., Demko, I.V., Verigo, Y.I., Кraposhina, А.Yu., Solovieva, I.А., & Hendogina, V.T. (2014). Markery sistemnogo vospaleniya i endotelialnoy disfunktsii u bolnykh khronicheskoy obstruktivnoy boleznyu legkikh [Markers of systemic inflammation and endothelial dysfunction in patients with chronic obstructive pulmonary disease]. Sibirskoye meditsinskoye obozreniye – Siberian Medical Review, 1, 12-16 [in Russian].
Kalantar, F., Rajaei, S., Heidari, A.B., Mansouri, R., Rashidi, N., Izad, M.H., & Mirahmadian, M. (2013). Serum levels of tumor necrosis factor-α, interleukin-15 and interleukin-10 in patients with pre-eclampsia in comparison with normotensive pregnant women. Iran J. Nurs. Midwifery Res., 18 (6), 463-466.
Aylamazyan, E.K., Polyakova, V.O., & Kvetnoy, I.M. (2012). Funktsionalnaya morfologiya platsenty cheloveka v norme i pri patologii (neyroimmunoendokrinologicheskiye aspekty) [Functional morphology of the human placenta in health and disease (neuroimmunoendocrinological aspects)]. Saint-Petersburg: Izd-vo N-L [in Russian].
Pavlova, N.G., Arzhanova, O.N., Zaynulina, M.S., & Kolobov, A.V. (2007). Platsentarnaya nedostatochnost: ucheb.-metod. posobiye [Placental insufficiency: study guide]. Aylamazyan, E.K. (Ed.). Saint-Petersburg: Izd-vo N-L [in Russian].
Sinopalnikov, A.I., & Fesenko, O.V. (2017). Vnebolnichnaya pnevmoniya [Community-acquired pneumonia]. Мoscow: GEOTAR-Media [in Russian].
Abuldinov, A.S. (2020). Osobennosti techeniya vnebolnichnoy pnevmonii u beremennykh [Features of the course of community-acquired pneumonia in pregnant women]. Proceedings of the XXI regional Scientific and Practical Conference «Molodezh XXI veka: shag v budushcheye» – "Youth of the XXI century: a step into the future". Blagoveshchensk: Izd-vo Dalnevost. gos. agrar. un-ta [in Russian].
Breton, M.C., Beauchesne, M.F., Lemière, C., Rey, E., Forget, A., & Blais, L. (2010). Risk of perinatal mortality associated with asthma during pregnancy: a 2-stage sampling cohort study. Ann. Allergy Asthma Immunol., 105 (3), 211-218. DOI: 10.1016/j.anai.2010.06.021.
Gorikov, I.N., Nakhamchen, L.G., & Kostromina, N.O. (2010). Sostoyaniye zdorovya novorozhdennykh ot materey s khronicheskim bronkhitom vne obostreniya [State of health of newborn from mothers with chronic bronchitis without exacerbation]. Byul. fiziologii i patologii dykhaniya – Bull. Physiology and Pathology of Respiration, 37, 53-55 [in Russian].
Chatterjee, P., Chiasson, V.L., Kopriva, S.E., Young, K.J., Chatterjee, V., Jones, K.A., & Mitchell, B.M. (2011). Interleukin-10 deficiency exacerbates toll-like receptor 3-induced preeclampsia-like symptoms in mice. Hypertension, 58 (3), 489-496. DOI: 10.1161/HYPERTENSIONAHA.111.172114.
Shilyayeva, E.G. (2012). Kliniko-morfologicheskiye osobennosti platsentarnoy nedostatochnosti u beremennykh s bronkhialnoy astmoy [Clinical and morphological features of placental insufficiency in pregnant women with bronchial asthma]. Candidate᾽s thesis. Kazan [in Russian].
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Actual Problems of Pediatrics, Obstetrics and Gynecology
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in this journal agree to the following terms:
1. The authors reserve the right to authorship of the work and pass the journal right of first publication of this work is licensed under a Creative Commons Attribution License, which allows others to freely distribute the work published with reference to the authors of the original work and the first publication of this magazine.
2. Authors are entitled to enter into a separate agreement on additional non-exclusive distribution of work in the form in which it was published in the magazine (eg work place in the electronic repository institution or publish monographs in part), provided that the reference to the first publication of this magazine.
3. Policy magazine allows and encourages authors placement on the Internet (eg, in storage facilities or on personal websites) manuscript of how to submit the manuscript to the editor and during his editorial processing, since it contributes to productive scientific discussion and positive impact on the efficiency and dynamics of citing published work (see. The Effect of Open Access).
