INTRODUCTION OF ELASTOGRAPHY FOR DIAGNOSIS OF HYPERPLASTIC PROCESSES IN GYNECOLOGY
DOI:
https://doi.org/10.11603/24116-4944.2021.1.12364Keywords:
elastography, proliferative processes, leiomyoma, polypAbstract
The aim of the study – to learn the effectiveness of elastography as an additional method of diagnosis during ultrasound examination of the pelvic organs in patients with hyperplastic processes of the uterus and endometrium; analyze the indicators of elastographic examination depending on the location of proliferation processes and the obtained results of elastographic indices; evaluate the indicators obtained for decision-making on treatment and conservative monitoring of this group of patients.
Materials and Methods. We examined 52 women of reproductive age from 24 to 40 years with hyperplastic processes of the uterus and endometrium, among them – 20 women with diffuse nodular, diffuse or nodular forms of uterine leiomyoma, 15 – with endometrial hyperplasia, 17 – with endometrial polyps. General clinical studies, ultrasound of the pelvic organs using elastography using ultrasound of the General Electric Voluson E8. In case of suspicion of atypical etiology of processes, a histopathological examination was performed.
Results and Discussion. It was shown that ultrasound elastography in patients with hyperplastic processes of the uterus and endometrium is an additional method of examination, which allows differentiating hyperplastic processes of the endometrium from the oncological process, verifies the morphological etiology of endometrial polyps, diagnoses the state of nodular and diffuse growths in uterine leiomyoma to control conservative management and treatment.
Conclusions. Ultrasound elastography is an additional examination method and allows to differentiate hyperplastic processes of the endometrium from an oncological process, makes it possible to assess the depth of invasion and determine the structure of the endometrium, which expands the possibilities of conservative observation. Elastography in the diagnosis of myometrium increases the verification of the state of the myometrium, identifies the morphological etiology of endometrial polyps by determining the density. Diagnoses the condition of nodular and diffuse growths in uterine leiomyoma for monitoring conservative management and treatment.
References
Gazhonova, V.E., Belozerova, I.S., Vorontsova, N.A., & Nadolnikova, T.A. (2013). Sonoelastografiya v diagnostike giperplasticheskikh protsessov endometriya [Sonoelastography in the diagnosis of endometrial pathology]. Meditsinskaya vizualizatsiya – Medical Imaging, 6, 57-65 [in Russian].
Gazhonova, V.E., Belozerova, I.S., Vorontsova, N.A., & Titov, D.S. (2014). Sonoelastografiya v diagnostike raka endometriya [Sonoelastography in the diagnosis of endometrial cancer]. Akusherstvo i ginekologiya – Obstetrics and Gynecology, 1, 54-58 [in Russian].
Golovko, T.S., & Bakay, O.A. (2014). Vozmozhnosti elastografii v diagnostike novoobrazovaniy sheyki matki [Possibilities of elastography for cervix tumors diagnostics]. Zdorovye zhenshchiny – Woman᾽s Health, 8 (94), 112-117 [in Russian].
Diomidova, V.N., Zakharova, O.V., & Petrova, O.V. (2015). Elastografiya sdvigovoy volnoy v otsenke endometriya i miometriya u zdorovykh zhenshchin reproduktivnogo vozrasta [Endometrium and myometrium shear wave elastography in healthy women of reproductive age]. Ultrazvukovaya i funktsionalnaya diagnostika – Ultrasound and Functional Diagnostics, 5, 51-56 [in Russian].
Rubtsova, N.A., Novikova, E.G., Puzakov, K.B., & Antipov, V.A. (2012). Magnitnorezonansnaya tomografiya v diagnostike raka sheyki matki [Role of magnetic resonance imaging in the diagnosis of cancer of the cervix uteri]. Rossiyskiy onkologicheskiy zhurnal – Russian Journal of Oncology, 2, 39-45 [in Russian].
Frantsevych, K.A. (2013). Sonoelastohrafiia yak metodyka v alhorytmi diahnostyky patolohichnykh utvorenykh hrudnoi zalozy [Sonoelastography as a technique in the algorithm of diagnostics of pathological formed breasts]. Visnyk Natsionalnoho tekhnichnoho universytetu Ukrainy “Kyivskyi politekhnichnyi instytut”. Ser. Pryladobuduvannia – Bulletin of the National Technical University of Ukraine "Kyiv Polytechnic Institute". Ser. Instrument making, 45, 180-190 [in Ukrainian].
Falou, O., Sadeghi-Naini, А., Prematilake, S., Sofroni, E., Papanicolau, N., Iradji, S., ..., & Czarnota, G.J. (2013). Evaluation of neoadjuvant chemotherapy response in women with locally advanced breast cancer using ultrasound elastography. Transl. Oncol., 6 (1), 17-24. DOI: 10.1593/tlo.12412.
Sadeghi-Naini, A., Falou, O., Hudson, J.M., Bailey, C., Burns, P.N., Yaffe, M.J., …, & Czarnota, G.J. (2012). Imaging innovations for cancer therapy response monitoring. Imaging Med., 4, 311-327.
Stavridis, S., Saidi, S., Lekovski, L., Dohcev, S., & Spasovski, G. (2010). Screening for prostate cancer: a controversy or fact. Hippokratia, 14 (3), 170-175.
Gorban, N.Ye., Zadorozhna, T.D., Vovk, I.B., & Zhulkevych, I.V. (2019). Morphological features of uterine polyps in females of reproductive age. Visnyk naukovykh doslidzhen – Bulletin of Scientific Research, 2, 47-52. DOI: https://doi.org/10.11603/2415-8798.2019.2.10267 [in Ukrainian].
Horban, N.Y., Vovk, I.B., Lysiana, T.O., Ponomariova, I.H., & Zhulkevych, I.V. (2019). Peculiarities of uterine cavity biocenosis in patients with different types of endometrial hyperproliferative pathology. J. Med. Life, 12 (3), 266-270. DOI: 10.25122/jml-2019-0074.
Bailey, C., Desmond, K.L., Czarnota, G.J., Stanisz, G.J. (2011). Quantitative magnetization transfer studies of apoptotic cell death. Magn. Reson. Med., 66 (1), 264-269. DOI: 10.1002/mrm.22820.
Gorban, N.Ye., Vovk, I.B., Hoida, N.H., & Linchak, O.V. (2019). Porushennia menstrualnoi funktsii: sytuatsiia v sviti i v Ukraini – u zhinok reproduktyvnoho viku ta z neatypovoiu hiperproliferatyvnoiu patolohiieiu endometriia [Menstrual dysfunction: the situation in the world and in Ukraine – in women of reproductive age and with atypical hyperproliferative pathology of the endometrium]. Visnyk sotsialnoi hihiieny ta orhanizatsii okhorony zdorovia Ukrainy – Bulletin of Social Hygiene and Health Protection Organization of Ukraine, 3 (81), 77-83. DOI: https://doi.org/10.11603/1681-2786.2019.3.10596 [in Ukrainian].
Lu, R., Xiao, Y., Liu, M., & Shi, D. (2014). Ultrasound elastography in the differential diagnosis of benign and malignant cervical lesions. J. Ultrasound Med., 33 (4), 667-671. DOI: 10.7863/ultra.33.4.667
Ciledag, N., Arda, K., Aktas, E., & Aribas, B.K. (2013). A pilot study on real-time transvaginal ultrasonographic elastography of cystic ovarian lesions. Indian J. Med. Res., 137 (6), 1089-1092.
Naftalin, J., Nunes, N., Hoo, W., Arora, R., & Jurkovic, D. (2012). Endometrial cancer and ultrasound: why measuring endometrial thickness is sometimes not enough. Ultrasound Obstet. Gynecol., 39 (1), 106-109. DOI: 10.1002/uog.9062.
Zubarev, A.V., Gazhonov, V.E., Churkina, S.O., Khokhlova, E.A., & Panfilova, E.A. (2009). Metodicheskiye rekomendatsii po ispolzovaniyu innovatsionnogo metoda sonoelastografii dlya poiska razlichnykh lokalizatsiy. Metodicheskoye rukovodstvo [Methodical recommendations for the use of an innovative method of sonoelastography to search for various localizations. Methodical guidance]. Moscow: Meditsina [in Russian].
Sigrist, R.M.S., Liau, J., Kaffas, A.E., Chammas, M.C., & Willmann, J.K. (2017). Ultrasound elastography: review of techniques and clinical applications. Theranostics, 7 (5), 1303-1329. DOI: 10.7150/thno.18650.
Gennisson, J.L., Deffieux, T., Fink, M., & Tanter, M. (2013). Ultrasound elastography: principles and techniques. Diagn. Interv. Imaging., 94 (5), 487-495. DOI: 10.1016/j.diii.2013.01.022.
Mitkov, V.V., Khuako, S.A., Ampilogova, Eh.R., & Mitkova, M.D. (2011). Otsenka vosproizvodimosti rezultatov kolichestvennoy ultrazvukovoy elastografii [Assessment of the shear wave elastography reproducibility]. Ultrazvukovaya i funktsionalnaya diagnostika – Ultrasound and Functional Diagnostics, 2, 115-120 [in Russian].
Guerriero, S., Ajossa, S., Orozco, R., Perniciano, M., Jurado, M., Melis, G.B., & Alcazar, J.L. (2016). Diagnostic accuracy of transvaginal ultrasoud for diagnosis of deep endometriosis in the recto-sigmoid: a meta-analysis. Ultrasound Obstet. Gynecol., 47 (3), 281-289. DOI: http://dx.doi.org/10.1002/uog.15662.
Metin, M.R., Aydın, H., Ünal, Ö., Akçay, Y., Duymuş, M., Türkyılmaz, E., & Avcu, S. (2016). Differentiation between endometrial carcinoma and atypical endometrial hyperplasia with transvaginal sonographic elastography. Diagn. Interv. Imaging, 97 (4), 425-431. DOI: 10.1016/j.diii.2015.11.007.
Stoelinga, B., Hehenkamp, W.J., Brölmann, H.A., & Huirne, J.A. (2014). Real-time elastography for assessment of uterine disorders. Ultrasound Obstet. Gynecol., 43 (2), 218-226. DOI: 10.1002/uog.12519.
Gultekin, I.B., Imamoglu, G.I., Turgal, M., Gultekin, S., Öcal, F.D., Alkan, A., & Kucukozkan, T. (2016). Elastosonographic evaluation of patients with a sonographic finding of thickened endometrium. Eur. J. Obstet. Gynecol. Reprod. Biol., 198, 105-109. DOI: 10.1016/j.ejogrb.2016.01.017.
Tessarolo, M., Bonino, L., Camanni, M., & Deltetto, F. (2011). Elastosonography: a possible new tool for diagnosis of adenomyosis? Eur. Radiol., 21 (7), 1546-1552. DOI: https://dx.doi.org/10.1007/s00330-011-2064-z.
Yusupov, K.F., Nedopekina, Ye.V., & Vikhareva, O.N. (2016). Primeneniye metoda elastografii v akushersko-ginekologicheskoy praktike [Use of elastography and gynekologic practice]. Akusherstvo i ginekologiya – Obstetrics and Gynecology, 11, 22-27. DOI: https://dx.doi.org/10.18565/aig.2016.11.22-7 [in Russian].
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