PECULIARITIES OF THE PERIMENOPAUSAL PERIOD IN WOMEN OF WESTERN UKRAINE DEPENDING ON THE PLACE OF RESIDENCE
DOI:
https://doi.org/10.11603/24116-4944.2021.1.12359Keywords:
perimenopausal period, menopausal symptoms, gynecological pathology, extragenital pathologyAbstract
The aim of the study – to learn the peculiarities of the functioning of the reproductive system of perimenopausal women in the study areas depending on their place of residence and taking into account the obstetric and gynecological history.
Materials and Methods. The prospective study included 138 women in the perimenopausal period of life (residents of cities (n=112) and villages (n=26)), who were comprehensively clinically examined for gynecological, extragenital pathology and serum vitamin D content.
Results and Discussion. Perimenopausal women had a history of life-threatening aggravating factors (allergic reactions, breast disease in the past, complicated history of reproductive function). The mean level of vitamin D in the sera of women in the general group did not correspond to a sufficient level (26.34±0.93) and was slightly higher on average in the group of women living in the city (27±1.04), and lower than the corresponding indicator in villagers (23.52±1.97). The average number of pregnancies prevailed in the rural population group, the number of stillborn pregnancies was significantly higher in women from the city (p≤0.01). Only (12.32±2.8) % of women had no gynecological diseases at the time of treatment. The range of gynecological lesions in patients was represented by 22 syndromes. No significant difference in the analyzed indicators in the comparison groups depending on the place of residence of women was found (p≤0.01).
According to the results of examinations in the dynamics of hyperpolymenorrhea (p=0.04) were found significantly more often in rural women; urethrocele, rectocele (p=0.04); non-inflammatory diseases of the female genital organs (p=0.04). No differences in the spectrum of other confirmed gynecological pathology, complaints in groups of women at the place of residence, were found (p≥0.05). The results of hormonal studies showed an imbalance of hormonal status in perimenopausal women and the risk of developing a number of pathological conditions associated with insulin resistance.
Conclusions. Presented current data on the peculiarities of the perimenopausal period in women of the study group showed the need for individualized management of patients, taking into account their obstetric, gynecological history and place of residence.
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