CORRELATION BETWEEN THE CLINICAL COURSE OF UTERINE LEIOMYOMA AND THE STATE OF GENITAL MICROBIOCENOSIS
DOI:
https://doi.org/10.11603/24116-4944.2021.1.12356Keywords:
infection, clinical course, reproductive ageAbstract
The aim of the study – the relationship between the clinical course of uterine leiomyoma and genital microbiocenosis disorders.
Materials and Methods. 246 women of reproductive age were examined, including 216 patients with clinically asymptomatic and symptomatic course of uterine leiomyoma. Genital microbiocenosis of these women was studied with bacterioscopic, bacteriological, and PCR methods.
Results and Discussion. 100 % of patients with uterine leiomyoma on the background of vaginitis constantly had heaviness, pain in the lower abdomen, sciatic syndrome, frequent urination. Up to 80 % of patients suffering from bacterial vaginosis with uterine leiomyoma reported pain in the lower abdomen and sciatic syndrome. In women with an intermediate type of genital microbiocenosis, these indicators were on average in 50 % of patients with uterine leiomyoma. In women with normocenosis, mild pain and discomfort in the lower abdomen were observed in only one patient during sexual intercourse in the asymptomatic uterine leiomyoma group. In the symptomatic uterine leiomyoma group, normocenosis was not detected, but vaginitis occurred twice as frequently as compared to the asymptomatic uterine leiomyoma group.
Conclusions. So, comparing the clinical course of uterine leiomyoma in women of reproductive age, depending on the state of vaginal microbiocenosis, the most pronounced clinical symptoms of uterine leiomyoma occurred in the group of patients with vaginitis. This does not exclude the role of the infectious factor in the uterine leiomyoma pathogenesis, the “false” growth of leiomyomatous nodes.
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