ASSESSMENT OF OVARIAN RESERVE IN WOMEN WITH INFERTILITY AND UTERINE LEIOMYOMA IN ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS
DOI:
https://doi.org/10.11603/24116-4944.2020.2.11844Keywords:
infertility, hormonal homeostasis, ultrasound monitoring, ovarian reserveAbstract
The aim of the study – to increase the incidence of pregnancy in infertile women with uterine leiomyoma by analyzing the main factors in the development of this pathology and optimizing the treatment and prevention complex.
Materials and Methods. A randomized prospective clinical study was conducted among 175 (29.0 %) women of reproductive age who were diagnosed with uterine leiomyoma (UL) and a control group (CG) of 32 somatically healthy women with normal menstrual and reproductive functions, who were divided into the following groups: Main Group (MG) A – 137 women with UL receiving the proposed treatment; Comparison Group (CG) B – 38 women with UL receiving conventional treatment.
Results and Discussion. The condition of the reproductive system was assessed using ultrasound and hormonal monitoring to predict the probable response of the ovaries to stimulation. The results of ultrasound and hormonal monitoring in women with infertility and uterine leiomyoma were evaluated in detail from a practical viewpoint to determine further treatment. Adequate blood circulation is an important factor for ovarian function. For patients where a “poor” ovarian response to controlled ovarian stimulation was predicted, the mean peak systolic velocity (PSV) in the stromal arteries was 1.68 times lower than in women from the control group. There was a positive correlation between the amount of injected gonadotropins, FSH levels and pulsatility index (0PI in the stromal arteries of the ovaries was (1.43±0.3).
Conclusion. A thorough assessment of the ovarian response allows the doctor to choose the correct treatment tactics and dose of drugs, as well as to monitor the results, taking into account the data obtained.
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