DIAGNOSIS OF TICK-BORNE INFECTIONS IN PREGNANT WOMEN

Authors

  • A. V. Boychuk I. Horbachevsky Ternopil National Medical University
  • Yu. B. Yakymchuk I. Horbachevsky Ternopil National Medical University
  • M. A. Andreychyn I. Horbachevsky Ternopil National Medical University
  • M. I. Skilna I. Horbachevsky Ternopil National Medical University
  • O. L. Ivakhiv I. Horbachevsky Ternopil National Medical University
  • I. M. Klishch I. Horbachevsky Ternopil National Medical University
  • M. M. Korda I. Horbachevsky Ternopil National Medical University
  • S. Yo. Zaporozhan I. Horbachevsky Ternopil National Medical University
  • M. T. Huk I. Horbachevsky Ternopil National Medical University
  • I. H. Sydorenko O. Bohomolets National Medical University, Kyiv

DOI:

https://doi.org/10.11603/24116-4944.2020.2.11837

Keywords:

tick-borne infections, antibodies and nucleic acids of pathogens, pregnant women, pathology of pregnancy

Abstract

The aim of the study – to determine the frequency of infection with B. burgdorferi sensu lato (s. l.), A. phagocytophilum, Babesia spp. and tick-borne encephalitis virus (ТВEV) of pregnant women in Ternopil region.

Materials and Methods. 43 pregnant women at 22–27 weeks of pregnancy, who had pathology of pregnancy, were examined. Specific IgM and IgG antibodies to B. burgdorferi s.l. were determined in blood serum by ELISA test, as well as DNA of: B. burgdorferi s. l. and A. phagocytophilum; RNA of: Babesia spp. and TBEV in the blood of pregnant women by real-time PCR.

Results and Discussion. Specific IgM and/or IgG antibodies to B. burgdorferi s. l. (B. burgdorferi sensu stricto, B. afzeli, B. garinii) by ELISA test were detected in the sera of 41.9 % of pregnant women. By PCR method DNA of B. burgdorferi s. l. found in the blood of 9.3 % in pregnant women; DNA of A. phagocytophilum – in 6.9 %, RNA of Babesia spp. – in 4.7 %, RNA TBEV – in 4.7 %.

Сonclusion. Detection of nucleic acids of tick-borne infections in pregnant women with pathology of pregnancy probably indicates the possible involvement of these pathogens in the occurrence of this pathology. Pregnant women can become infected by consuming uncooked goat's and cattle milk.

Author Biographies

A. V. Boychuk, I. Horbachevsky Ternopil National Medical University

Doctor of Medical Sciences, Professor, Head Department of Obstetrics and Gynaecology, Institute of Postgraduate Education I. Horbachevsky Ternopil National Medical University

Yu. B. Yakymchuk, I. Horbachevsky Ternopil National Medical University

Master of Medicine, Assistant Department of Obstetrics and Gynecology, Institute of Postgraduate Education I. Horbachevsky Ternopil National Medical University

M. A. Andreychyn, I. Horbachevsky Ternopil National Medical University

Doctor of Medical Sciences, Professor, academician of the National Academy of Medical Sciences of Ukraine, Head Department of Infectious Diseases and Epidemiology, Dermatology and Venereology, I. Horbachevsky Ternopil National Medical University

M. I. Skilna, I. Horbachevsky Ternopil National Medical University

PhD, associate professor of the Departmentof Infectious Diseases and Epidemiology, Dermatology and Venereology, I. Horbachevsky Ternopil National Medical University

O. L. Ivakhiv, I. Horbachevsky Ternopil National Medical University

PhD, аssociate рrofessor of Department of Infectious Diseases with Epidemiology, Dermatology and Venereology, I. Horbachevsky Ternopil Nacional Medical University

I. M. Klishch, I. Horbachevsky Ternopil National Medical University

Merited Figure of Science and Technology of Ukraine, Doctor of Biological Sciences, Professor Department of Functional and Laboratory Diagnostics, Vice-Rector I. Horbachevsky Ternopil National Medical University

M. M. Korda, I. Horbachevsky Ternopil National Medical University

MD, Ph.D., DSc, professor Medical Biochemistry Department, Rector, I. Horbachevsky Ternopil National Medical University

S. Yo. Zaporozhan, I. Horbachevsky Ternopil National Medical University

Doctor of Medical Sciences, Professor of the Department General Surgery I. Horbachevsky Ternopil National Medical University

M. T. Huk, I. Horbachevsky Ternopil National Medical University

MD, Postgraduate Department of Infectious Diseases, Epidemiology and Dermatovenereology, I. Horbachevsky Ternopil National Medical University

I. H. Sydorenko, O. Bohomolets National Medical University, Kyiv

Candidate of Medical Sciences, Associate Professor of Therapeutic Dentistry Department, Bogomolets National Medical University, Kyiv

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Published

2021-03-04

How to Cite

Boychuk, A. V., Yakymchuk, Y. B., Andreychyn, M. A., Skilna, M. I., Ivakhiv, O. L., Klishch, I. M., … Sydorenko, I. H. (2021). DIAGNOSIS OF TICK-BORNE INFECTIONS IN PREGNANT WOMEN. Actual Problems of Pediatrics, Obstetrics and Gynecology, (2), 50–55. https://doi.org/10.11603/24116-4944.2020.2.11837

Issue

No. 2 (2020)

Section

OBSTETRICS AND GYNECOLOGY

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