Blood lipid profile of female and male rats in case of toxic cardiomyopathy, due to the introduction of sodium nitrite
DOI:
https://doi.org/10.11603/mcch.2410-681X.2016.v0.i4.7275Keywords:
lipids, blood, sodium nitrite.Abstract
The indices of the blood plasma lipid profile of female and male rats in case of toxic cardiomyopathy, due to the introduction of sodium nitrite were sudied. It was determined the increasing of cholesterol concentration in the blood plasma and its redistribution between lipoproteins due to reduction in high density lipoproteins and an increase in low-density lipoprotein, which have proatherogenic properties in animals of both sexes. In gender comparison of changes in blood lipid profile in case of sodium nitrite intoxication their significant prevalence in male rats was found.
References
Akopian L. G. Vosstanovlenie nitratov v zheludochno-kishechnom trakte – risk kantcerogennogo deistviia / L. G. Akopian, Iu. T. Aleksanian // Meditcinskaia nauka Armenii NAN RA. – 2010. – № 3. – S. 52–58.
Dzotcieva L. Kh. Vliianie atcizola na funktcii pochek i gematologicheskie pokazateli pri eksperimentalnoi nitritnoi intoksikatcii : avtoref. dis. na zdobuttia nauk. stupenia kand. med. nauk / L. Kh. Dzotcieva ; GOU VPO “Sev.-Oset. gos. med. akad. FAZ i SR”. – Vladikavkaz, 2010. – 22 s.
Dinamika diureza i gistomorfologicheskikh izmenenii pochek u belykh krys pri khronicheskoi intoksikatcii nitritom natriia / L. A. Akoeva, L. A. Gireeva, I. G. Dzhioev, L. S. Tabolova // Zhurn. anatomii i gistopatologii. – 2012. – 1, № 4. – S. 63–65.
Analiz vmistu kharchovykh dobavok u produktakh kharchuvannia ta yikh nebezpeky dlia zdorov’ia spozhyvachiv [Elektronnyi resurs] / L. Ia. Ivashkiv, M. Ia. Bomba, A. Ie. Shakh [ta in.]. – 2013. – Rezhym dostupu: http://www.sworld.com.ua/konfer33/1213.pdf.
Dinamika pokazatelei lipidnogo obmena u krys s modeliu toksicheskogo gepatita bez lecheniia i na fone priema masla orekha chernogo (Juglands nigra L.) / E. E. Esaulenko, M. I. Bykov, A. A. Ladutko, S. S. Bachko // Allergologiia i immunologiia. – 2009. – 10, № 2. – S. 289.
Zerbino D. D. Koronarna khvoroba sertsia ta infarkt miokarda u khvorykh molodoho viku: rol ksenobiotykiv (fakty, hipotezy, komentari) / D. D. Zerbino, T. N. Solomenchuk, V. A. Skybchyk // Ukr. kardiol. zhurn. – 2003. – № 1. – S. 14–20.
Kaminskyi R. F. Okysno-vidnovni protsesy yak osnova rozvytku patolohichnykh zmin miokarda ta vazhlyva lanka likuvalnoi dii farmpreparativ za khronichnoi rtutnoi intoksykatsii / R. F. Kaminskyi, N. А. Kolesova, Iu. B. Chaikovskyi // Ukr. morfol. alm.– 2010. – Том 8, № 2. – С 81–84.
Kamyshnikov V. S. Spravochnik po kliniko-biokhimicheskim issledovaniiam i laboratornoi diagnostike / V. S. Kamyshnikov. – M. : MEDpress-inform, 2009. – 896 s.
Morfologicheskie kharakteristiki serdtca krys v usloviiakh eksperimentalnogo nekroza miokarda / T. V. Shkand, N. A. Chizh, O. V. Naumova, B. P. Sandomirskii // Morfologіia. – 2013. – VІІ, № 2. – S. 84–89.
Naukovo-praktychni rekomendatsii z utrymannia laboratornykh tvaryn ta roboty z nymy / Iu. M. Kozhem’iakin, O. S. Khromov, M. A. Filonenko, H. A. Saifetdinova. – K. : Avitsena, 2002. – 156 s.
Natcionalnye rekomendatcii OSSN, RKO i RNMOT po diagnostike i lecheniiu KhSN (chetvertyi peresmotr) / V. Iu. Mareev, F. T. Ageev, G. P. Arutiunov [i dr.] // Zhurnal Serdechnaia Nedostatochnost. – 2013. – 14, № 7 (81). – S. 379–571.
Sikora V. Z. Vikovi osoblyvosti morfofunktsionalnykh peretvoren miokarda v normi ta v umovakh vplyvu ushkodzhuvalnykh chynnykiv (ohliad literatury) / V. Z. Sikora, O. S. Yarmolenko // Zhurn. klinich. ta eksperym. med. doslidzh. – 2013. – 1, № 3 – S. 263–274.
Shchorichna dopovid pro stan zdorov’ia naselennia Ukrainy, sanitarno-epidemichnu sytuatsiiu ta rezultaty diialnosti systemy okhorony zdorov’ia Ukrainy. 2014 rik / za red. O. Kvitashvili ; MOZ Ukrainy, DU “UISD MOZ Ukrainy” – K., 2015. – 460 s.
Ianovich V. G. Obmen lipidov u zhivotnykh v ontogeneze / V. G. Ianovich, P. Z. Lagodiuk. – M. : Agropromizdat, 1991. – 316 s.
Bioavailability of sodium nitrite from an aqueous solution in healthy adults / C. C. Hunault, A. G. van Velzena, A. Sips [et al.] // Toxicol. Lett. – 2009. –190. – Р. 48–53.
European convention for the protection of vertebrate animals used for experimental and other scientific purposes. – Council of Europe. Strasbourg. – 1986. – № 123. – 52 p.
Ferguson L. R. Meat and cancer / L. R. Ferguson // Meat Sci. – 2010. – 84. – Р. 308–313.
Fredrickson D. S. Fat transport in lipoproteins - an integrated approach to mechanisms and disorders / D. S. Fredrickson, R. I. Levy, R. S. Lees // N. Engl. J. Med. – 1967. – 276. – Р. 34–44.