Activity of glutathione-dependent enzymes in spermatozoa in patients with pathospermia
DOI:
https://doi.org/10.11603/mcch.2410-681X.2016.v0.i4.7246Keywords:
sperm, antioxidant system, hydrogen peroxide, reactive oxygen species, glutathione peroxidase, glutathione reductase, male infertility.Abstract
The results of glutathione peroxidase and glutathione reductase activity in spermatozoa of patients with different forms pathospermia are presented in the paper. It was shown that glutathione peroxidase and glutathione reductase activity in sperm cells of patients is reduced in comparison with healthy men with preserved fertility. However, the most expressed changes in the activity of glutathione peroxidase and glutathione reductase are in spermatozoa of infertile men with associated forms patospermia and leucospermia. These changes indicate exhaustion of compensatory mechanisms of glutathione antioxidant system in the sperm cells of infertile men with pahospermia.
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