The state of the prooxidant-antioxidant system in the stomach of rats with modeling chemical gastritis under short-term and long-term hypomelatoninemy
DOI:
https://doi.org/10.11603/mcch.2410-681X.2016.v0.i3.6947Keywords:
prooxidant-antioxidant system, hypomelatoninemy, stomach, chemical gastritis.Abstract
We studied the changes occurring in the prooxidant-antioxidant system of the stomach with a lowered level of melatonin and with modeling chemical gastritis. The experiment found changes in indicators of prooxidant-antioxidant system in the stomach in a simulation of chemical gastritis against the background of short-term and long-term lack of melatonin. It is proved that the lack of synthesis of melatonin increases the content of peroxidation products reduce activity of enzymes and leads to imbalance of the antioxidant system of the stomach of white rats at long-term experiment, causing oxidative stress.
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