ETIOLOGICAL FACTORS WHICH FORM THE CHRONICAL PANCREATITIS

Abstract

Chronic pancreatitis (CP) is one of the most common gastrointestinal diseases, accounting for about 8–10 % in the structure of all gastroenterological diseases of the digestive system. Often this disease is diagnosed late (alcohol icnature – up to 30 months, an other etiology – up to 60 months from the beginning of the disease). In recent years, the incidence of CP has increased, which is accompanied by structural changes leading to exo-and endocrine pancreatic insufficiency, characterized by a deterioration in the quality of life and a relatively high risk of developing diabetes and pancreatic tumors. Ten years after the diagnosis of CP, approximately 25 % of patients are forced to leave their professional activities and become disabled. This develops the external secretory deficiency of the prostate, suffers from digestion due to the formation of maldigestion (syndrome of impaired absorption) and malabsorption (syndrome of impaired absorption). Knowledge of etiologic factors (tobacco smoking, alcoholism, infectious, viral factors, helminthic nausea, cholelithiasis, chronic renal failure, etc.) are important not only for diagnosis, but also for clinical course, differential diagnosis, treatment, rehabilitation activities and prognosis of the course of the disease.