FEATURES OF THE CLINICAL PICTURE AND ANTHROPOMETRIC INDICES IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE

Authors

  • I. V. Chopey State Higher Education Establishment "Uzhhorod National University"
  • K. I. Chubyrko State Higher Education Establishment "Uzhhorod National University"
  • T. I. Griadil State Higher Education Establishment "Uzhhorod National University"
  • V. V. Ivachevska State Higher Education Establishment "Uzhhorod National University"

DOI:

https://doi.org/10.11603/1811-2471.2018.v0.i2.8687

Keywords:

non-alcoholic fatty liver disease, pre-diabet, type 2 diabetes mellitus.

Abstract

The work is devoted to the study of the features of the clinical picture of nonalcoholic steatosis and steatohepatitis in patients with pre-diabetes and type 2 diabetes mellitus (DM). A survey of 117 patients with a background of NADH and pre-diabetes and type 2 diabetes was performed. The prevalence of non-alcoholic steatosis and steatohepatitis in patients with pre-diabetes was studied. It has been shown that patients with NAGHP and pre-diabetes should be classified as very high cardiovascular risk (CD). The peculiarities of carbohydrate and lipid metabolism in patients with NADH on the background of pre-diabetes and type 2 diabetes were studied.

Material and Methods. This work reflects the results of a comprehensive survey of 141 patients with type 2 diabetes and pre-diabetes.

Results. The leading symptoms in patients with NADH are nausea, pain, flatulence and stomach upsets. Significant differences between patients in groups I and II were detected only with complaints such as: flatulence, general weakness, sense of bitterness in the oral cavity and nausea.

Conclusions NSCLC was diagnosed in 98.4 % of patients with type 2 diabetes, including steatosis in 54.84 %, and steatohepatitis in 45.16 %. In persons with pre-diabetic NADH, 70.5 % were established, of which 85.45 % were steatosis and 14.55 % were steatohepatitis (p<0.05). The features of the clinical picture of NADH are oligosymptomy, comorbidity and the predominance of dyspeptic syndrome (flatulence was found in 43.59 %, pain in the right hypochondrium and discomfort in the abdominal cavity – 29.91 % and 28.21 % respectively, and a feeling of bitterness in the oral cavity – by 21.37 %). 

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Published

2018-08-02

How to Cite

Chopey, I. V., Chubyrko, K. I., Griadil, T. I., & Ivachevska, V. V. (2018). FEATURES OF THE CLINICAL PICTURE AND ANTHROPOMETRIC INDICES IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE. Achievements of Clinical and Experimental Medicine, (2). https://doi.org/10.11603/1811-2471.2018.v0.i2.8687

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Section

Оригінальні дослідження