PREDICTION THE RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH STABLE ANGINA PECTORIS AND GASTROESOPHAGEAL REFLUX DISEASE DURING ESOPHAGOGASTRODUODENOPHIBROSCOPY
DOI:
https://doi.org/10.11603/1811-2471.2018.v0.i2.8641Keywords:
stable angina pectoris, gastroesophageal reflux disease, Ch. D. Spielberger and Yu. L. Hanina questionnaire, cardiac symptoms, medication preparation.Abstract
The aim of the study – to determine the incidence of cardiac symptoms and the need for the medical preparation of patients with stable angina pectoris (SAP) for comorbidity with GERD when conducting esophagogastroduodenofibroscopy (EGDFS)
Material and Methods. We examined 44 patients with SAP, I–II FC with comorbid GERD who already had experience in conducting endoscopic examination. The age of the patients varied from 48 to 79 years. Patients did not receive any medication preparation for EGDFS. The actual endoscopic examination was carried out in the morning, on an empty stomach, one hour after awakening under ECG control. All patients in the evening of the day preceding the day of endoscopic diagnosis were asked to pass a test of Ch.D. Spielberger and Yu. L. Hanina.
Results. It was found that the average value in the study group for both reactive and personal anxiety was in the range of 31–45 points, which corresponds to moderate anxiety. The incidence of cardiac symptoms in the study group was 77.2 % (35 patients) during EHDPS. Based on the results of the repeated analysis of the results of testing of patients who had this or that cardiac symptomatology, the limiting score of the two subscales of the Spielberger–Hanin questionnaire was established, which is 75 points, when it reaches or exceeds which there is a high risk of developing certain cardiac symptoms in patients with SAP and GERD in the conduct of EHDRS, and these patients need medical treatment for endoscopic diagnostic. Dependence between the ratio of subscales in the sum is not established.
Conclusion. The incidence of cardiac symptoms in EHDPS patients with CHF and GERD is 77.2 %. It is recommended to diagnose anxiety with the help of the Spielberger-Khanin questionnaire in the evening of the day preceding the day of the study in order to establish the risk of cardiovascular events in the course of EGDFS. If, in sum, the results of the two subscales of the Spielberg-Khanin questionnaire were 75 points, then the risk of cardiac symptoms during EGDFS was high and these patients need medical preparations for EGMDS.
References
Nakaz MOZ Ukrainy № 152 vid 02.03.2016 r. “Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi), tretynnoi (vysokospetsializovanoi) medychnoi dopomohy. Stabilna ishemichna khvoroba sertsia”. – Retrieved from: http://www.moz.gov.ua/ua/portal/dn_20160302_0152.html [in Ukrainian].
Nakaz MOZ Ukrainy № 943 vid 31.10.2013 roku “Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi) medychnoi dopomohy hastroezofahealna refliuksna khvoroba”. – 2013. – [Elektronnyi resurs]. – Retrieved from: http://www.moz.gov.ua/ua/portal/dn_20131031_0943.html [in Ukrainian].
Khukhlina, O.S., & Drozd, V.Iu. (2017). Dosvid zastosuvannia meldoniiu u kompleksnii terapii khvorykh na stabilnu stenokardiiu napruhy ta hastroezofahealnu refliuksnu khvorobu [Experience of the use of meldonium in a complex therapy of patients with stable tension steno cardia and gastroesophageal reflux disease]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of Clinical and Experimental Medicine, 2, 84-88. DOI 10.11603/1811-2471.2017.v0.i2.7732 [in Ukrainian].
Rodionova, V.V., & Kovalenko, E.N. (2016). Korektsiia endotelialnoi dysfunktsii v terapevtychnii stratehii sertsevo-sudynnoi patolohii [Correction of endothelial dysfunction in therapeutic strategy of cardio-vascular pathology]. Kardiologiya: ot nauky k praktike – Cardiology: from Science to Practice, 2 (21), 31-38 [in Ukrainian].
Khaustova, O.O. (2017). Neiroimunoendokrynolohiia: suchasnyi pohliad na psykhosomatychnyi dialoh liudyny zi stresom [Neuroimmunoendocrinology: modern view on psychosomatic dialogue of a person with stress]. Liky Ukrainy – Drugs of Ukraine, 1 (207), 10-16 [in Ukrainian].
Chaban, O.S. (2015). Stres: a yakyi preparat pryznachyv by Hans Selie? [What kind of drug would Hans Selie prescribed?]. Simeina medytsyna – Family Medicine, 3 (59), 95-99 [in Ukrainian].
Kupriyanov, R.V., & Kuzmina, Yu.M. (2012). Psikhodiagnostika stressa: praktikum [Psychodiagnostics of stress: practical guide]. M-vo obraz. i nauky RF, Kazan. gos. tekhnol. un-t. - Kazan: KNYTU [in Russian]
Eliseev, O.P. (2000). Praktikum po psikhologii lichnosti [Practical guide on personality psychology]. Saint Petersburg: Izd-vo “Piter” [in Russian].
Chauhan, A., Mullins, P.A., Taylor, G., Petch, M.C., & Schofield, P.M. (1996). Cardioesophageal reflex: а mechanism for “linked angina” in patients with angiographically proven coronary artery disease. J. Am. Coll. Cardiol., 27 (7), 1621-1628. Available from: https://www.sciencedirect.com/science/article/pii/0735109796000411 DOI:10.1016/0735-1097(96)00041-1
Crina, R., Bruley des Varannes, S., Muresan, L., & Picos, A. (2014). Atrial fibrillation in patients with gastroesophageal reflux disease: A comprehensive review. World J. Gastroenterol., 20 (28), 9592-9599. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110594/ DOI:10.3748/wjg.v20.i28.9592
Dobrzycki, S., Baniukiewicz, A., Korecki, J., Bachórzewska-Gajewska, H., Prokopczuk, P., & Musial, W. (2005). Does gastro-esophageal reflux provoke the myocardial ischemia in patients with CAD? Intern. J. of Card, 104 (1), 67-72. Available from: http://www.internationaljournalofcardiology.com/article/S0167-5273(05)00139-7/pdf DOI:10.1016/j.ijcard.2004.10.018
Floria, M., Barboi, O., Rezus, C., Ambarus, V., Cijevschi-Prelipcean, C., Balan, G. (2015). Atrial fibrillation and gastro-oesophageal reflux disease - controversies and challenges. Curr. Pharm. Des., 21 (26), 3829-3834. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25786404 DOI: 10.2174/1381612821666150319100003
Gerson, L.B., Friday, K., & Triadafilopoulos, G. (2006). Potential relationship between gastroesophageal reflux disease and atrial arrhythmias. J. Clin. Gastroenterol., 40 (9), 828-832. Available from: https://www.ncbi.nlm.nih.gov/pubmed/17016140 DOI: 10.1097/01.mcg.0000225571.42890.a5
Hwang, J.J., Lee, D.H., Yoon, H., Shin, C.M., Park, Y.S., & Kim, N. (2015). Is atrial fibrillation a risk factor for gastroesophageal reflux disease occurrence? Medicine (Baltimore), 94 (43), e1921. – Available from: (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985431/ DOI: 10.1097/MD.0000000000001921.
Linz, D., Hohl, M., Vollmar, J., Ukena, C., Mahfoud, F., & Böhm, M. (2017). Atrial fibrillation and gastroesophageal reflux disease: the cardiogastric interaction. EP Europace [Internet], 19, (1), 16-20. – Available from: https://academic.oup.com/europace/article/19/1/16/2952312 DOI: 10.1093/europace/euw092
Rosztóczy, A., Vass, A., Izbéki, F., Nemes, A., Rudas, L., & Csanády, M. (2007). The evaluation of gastro-oesophageal reflux and oesophagocardiac reflex in patients with angina-like chest pain following cardiologic investigations. Intern. J. of Card, 118 (1), 62-68. – Available from: https: //www.sciencedirect.com/science/article/pii/S0167527306006206 DOI: 10.1016/j.ijcard.2006.05.035
Shirzad, M., Mosaddegh, M., Minaii, B., Nikbakht Nasrabadi, A., & Ahmadian-Attari, M.M. (2013). The relationship between heart and stomach in Iranian traditional medicine: a new concept in cardiovascular disease management. Intern. J. of Card, 165 (3), 556-557. – Available from: https://mafiadoc.com/the-relationship-between-heart-and-stomach-in-_59d24a511723dd752f6a0381.html DOI: 10.1016/j.ijcard.2012.09.006
Tougas, G., Spaziani, R., Hollerbac, S., Djuric, V., Pang, C., & Upton, A. (2001). Cardiac autonomic function and oesophageal acid sensitivity in patients with non-cardiac chest pain. Gut, 49 (5), 706-712. – Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1728517/ DOI: 10.1136/gut.49.5.706
Velagapudi, P., Turagam, M.K., Leal, M.A., & Kocheril, A.G. (2012). Atrial fibrillation and acid reflux disease. Clin. Cardiol., 35 (3), 180-186. – Available from: https://www.ncbi.nlm.nih.gov/pubmed/22318757 DOI: 10.1002/clc.21969