FEATURES OF PNEUMONIA COURSE IN ONCOLOGICAL BLOOD DISEASES
DOI:
https://doi.org/10.11603/1811-2471.2018.v0.i1.8610Keywords:
pneumonia, oncological diseases of the blood, infectious pathogens.Abstract
The most common infectious complications of leukemia are pneumonia, which is often the main cause of the death of these patients.
The aim of the work was to determine the etiological factor of pneumonia in patients with severe immune disorders on the background of oncological diseases of the blood.
Material and Methods. 124 patients with pneumonia and oncological diseases of the blood were examined. A microbiological study of sputum and fluid of bronchoalveolar lavage was determined by studying native smears with the definition of the main morphological types of pathogens.
Results. According to the results of microbiological studies, probable bacterial pathogens of the disease were identified in 69.4 % of cases. Among the 89 positive results of microbiological research, gram-negative microorganisms were the leading, accounting for 68.6 %. Gram-positive microorganisms were identified in 26.7 % of the studies. Associations of pathogenic microgranisms have been identified in 53.3 % of patients in the study group: with fungal flora – 52.4 %; the association of bacteria – 26.7 %.
References
Avdeev SN. Application of the method of induced sputum for evaluation of intensity of respiratory tract inflammation / Anaev EKh, Chuchalin A.G.// Pulmo-nologiya.-2010.-№4.-Р. 81-87.
Dzyublik YaO. Clinical aspects of resistence of antimicrobial agents of community acquired respiratory tract infections. //Ukrai'ns'kiy pul'monologichniy zhurnal. -2010.-№3.-Р.53-56.
Non-hospital pneumonia in adults: etiology, pathogenesis, classification, diagnosis, antibiotic bacterial therapy (Project of clinical guidelines) / Yu.I. Feshchenko, OA Golubovskaya, K.A. Goncharov, O.Ya. Dzublyk // Ukrai'ns'kiy pul'monologichniy zhurnal.-2012.-№4.-p.5-17.
Pertseva T.O. Pneumonia in patients with background of oncological diseases of blood / T.O.Pertseva, I.S. Borisova // Clinical Medicine.-2014. №14 Volume XIX / 1.-P.45-49.
Shorr A.F. Quality pneumonia care: distinguishing community-acquired from health careassociated pneumonia/ A.F. Shorr, R.C. Owens // Am. J. Health Syst. Pharm.-2009.-Vol.66,N12,Suppl.4.-P.8-14.