FEATURES OF REMODELING OF LEFT AND RIGHT HEART IN PATIENTS WITH COMBINATION OF ISCHEMIC HEART DISEASE AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE.
DOI:
https://doi.org/10.11603/1811-2471.2017.v1.i3.8023Keywords:
stable ischemic heart disease, chronic obstructive pulmonary disease, echocardiography, cardiac remodeling.Abstract
Ischemic heart disease (IHD) and chronic obstructive pulmonary disease (COPD) are common diseases in Ukraine and in the world. Both diseases are characterized by different structural-geometrical changes of heart compartments, for this reason knowledge of features of echocardiographic parameters in case of comorbidity is important.
The aim of the study was to determine features of remodeling of heart compartments in patients with combination of stable IHD and COPD, to establish differences from indices of patients with isolated course of these diseases.Materials and Methods. The study included 98 patients with combination of stable IHD and COPD, 96 patients with stable IHD without concomitant COPD and 78 patients with COPD without IHD. Typical clinical examination, M- and B-mode echocardiography were conducted.
Results. Patients with combined pathology were found more pronounced process of left ventricle remodeling (concentric hypertrophy in 21.4 %, eccentric hypertrophy in 23.5 %), increase of left ventricular wall thickness, the tendency to decrement of left ventricular ejection fraction as compared to patients with IHD. Changes of right heart of patients with IHD and COPD were distinguished from indices of patients with isolated COPD, that is significantly bidder right atrium and increase in the proportion of people with III type of right ventricle remodeling –pressure and volume overload in 79.6 %.Conclusions. Determined changes are illustrative of reciprocal influence of IHD and COPD. Cardiac remodeling in case of combined pathology differs from indices of patients with isolated course of these diseases.
References
Moz.gov.ua. (2013) Nakaz MOZ Ukrainy №555 «Pro zatverdzhennia ta vprovadzhennia medyko-tekhnolohichnykh dokumentiv zi standartyzatsii medychnoi dopomohy pry khronichnomu obstruktyvnomu zakhvoriuvanni lehen» vid 27.06.2013. Access mode http://moz.gov.ua/ua/portal/dn_20130627_0555.html [in Ukranian]
Sanchis-Gomar, F., Perez-Quilis, C., Leischik, R. and Lucia, A. (2016). Epidemiology of coronary heart disease and acute coronary syndrome. Annals of Translational Medicine, 4(13), pp.256-256.
Bosch, L., Lam, C., Gong, L., Chan, S.P., Sim, D., Yeo, D. (2017). Right ventricular dysfunction in left-sided heart failure with preserved versus reduced ejection fraction. Eur J Heart Failure.
Mohammed, S., Hussain, I., Abou Ezzeddine, O., Takahama, H., Kwon, S., Forfia, P., Roger, V. and Redfield, M. (2014). Right Ventricular Function in Heart Failure With Preserved Ejection Fraction: A Community-Based Study. Circulation, 130(25), pp.2310-2320.
Meyer, P., White, M. and Ali, A. (2009). Effect of Reduced Right Ventricular Ejection Fraction on Mortality in Advanced Systolic Heart Failure. Journal of Cardiac Failure, 15(6), pp.88-89.
Global Initiative for Chronic Obstructive Lung Disease (Updated 2017) [ Electronic Resource] / Access mode : www.goldcopd.com
Moz.gov.ua. (2016) Nakaz MOZ Ukrainy №152 «Pro zatverdzhennia ta vprovadzhennia medyko-tekhnolohichnykh dokumentiv zi standartyzatsii medychnoi dopomohy pry stabilnii ishemichnii khvorobi sertsia» vid 02.03.2016. Access mode http://moz.gov.ua/ua/portal/dn_20160302_0152.html [in Ukranian]
López-Sánchez, M., Muñoz-Esquerre, M., Huertas, D., Gonzalez-Costello, J., Ribas, J., Manresa, F., Dorca, J. and Santos, S. (2013). High Prevalence of Left Ventricle Diastolic Dysfunction in Severe COPD Associated with A Low Exercise Capacity: A Cross-Sectional Study. PLoS ONE, 8(6), pp.135-142.
Paudel, B., Dhungel, S., Paudel, K., Pandru, K., Paude, R. (2008) When left ventricular failure complicates chronic obstructive pulmonary disease: hypoxia plays the major role. Kathmandu Univ. Med. J. (KUMJ), 6(1), pp.37-40.
Roversi, S., Roversi, P., Spadafora, G., Rossi, R. and Fabbri, L. (2013). Coronary artery disease concomitant with chronic obstructive pulmonary disease. European Journal of Clinical Investigation, 44(1), pp.93-102.
Andell, P., Koul, S., Martinsson, A., Sundström, J., Jernberg, T., Smith, J., James, S., Lindahl, B. and Erlinge, D. (2014). Impact of chronic obstructive pulmonary disease on morbidity and mortality after myocardial infarction. Open Heart, 1(1), p.e000002.
