BONE MINERAL DENSITY AND FREQUENCY OF ОSTEOPOROSIS IN UKRAINIAN WOMEN WITH METABOLIC SYNDROME
DOI:
https://doi.org/10.11603/1811-2471.2016.v0.i4.7084Keywords:
osteoporosis, bone mineral density, obesity, metabolic syndrome.Abstract
The purpose of the study was to determine the frequency of osteoporosis and low bone mineral density (BMD) in Ukrainian women. The study involved 1009 persons. The mean age of them was 63.2±9.0 years; the mean weight was 70.9±12,3kg. All women were in postmenopausal period. Patients were compared into two groups. Соntrol group included women without obesity (755 people), another group involved patients with metabolic syndrome (254 people). BMD of lumbar spine, femoral neck, ulna radius, total body was measured by dual-energy X-ray absortiometry, (Prodigy, 2005 yr.). Women were considered to have normal or decreased BMD according to criteria of the Official Positions of the ISCD, 2007 year (updated in 2015 year). Data were analyzed using Statistical Package 6.0 BMD, frequency of normal and decreased BMD, osteoporosis were examined in both groups of the patients. Our study estimated that frequency of osteoporosis and low BMD is much rare in patients with metabolic syndrome compared to women without obesity.
References
Zahayko A. L. Metabolichnyy syndrom: mekhanizmy rozvytku ta perspektyvy antyoksydantnoyi terapiyi : monohrafiya / A. L. Zahayko, L. M. Voronina, K. V. Strelʹchenko. – KH. : Vyd-vo NFaU: «Zoloti storinky», 2007. – 216 s.
Makolkyn V. Y. Metabolycheskyy syndrom / V. Y. Makolkyn. – M. : OOO «Medytsynskoe ynformatsyonnoe ahent·stvo», 2010. – 144 s.
Mamedov M. N. Kak predupredytʹ rysk razvytyya yshemycheskoy bolezny serdtsa y sakharnoho dyabeta? (Master-klass po vedenyyu patsyenta s metabolycheskym syndromom) / M. N. Mamedov // Mezhdunarodnyy éndokrynolohycheskyy zhurnal. – 2007. – № 5 (11). – S.47–60.
Osteoporoz: klynyka, dyahnostyka, profylaktyka y lechenye / N. A. Korzh, V. V. Povoroznyuk, N. V. Dedukh, Y. A. Zupanets. – Kharʹkov : Zolotye stranytsy, 2002. – 486 s.
Povoroznyuk V. V. Menopauza ta osteoporoz / V. V Povoroznyuk, N. V. Hryhorʺyeva. – K. : Ekspres, 2004. – 356 s.
Povoroznyuk V. V. Zvʺyazok mineralʹnoyi shchilʹnosti kistkovoyi tkanyny ta stanu lipidnoho obminu u zhinok zalezhno vid tryvalosti postmenopauzy / V. V Povoroznyuk, O. I Nishkumay // Problemy starenyya y dolholetyya. – 2009. – T. 18, № 4. – S. 412–424.
Alberti K. G. Definition, diagnosis and classification of diabetes mellitus and its complications: Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation / K. G. Alberti, P. Z. Zimmet // Diabet Med. – 1998. – Vol. 15(7). – P. 539–553. PMID:9686693 [PubMed - indexed for MEDLINE].
Effect of raised body fat on vitamin D, leptin and bone mass / S. S. Fatima, S. Farooq, M. A. Tauni [et al.] // J. Pak. Med. Assoc. – 2015. – Vol. 65(12). – P. 1315–1319. PMID:26627514.
Central and peripheral fat body mass have a protective effect on osteopenia or osteoporosis in adults and elderly? Osteoporos Int. / P. M. Freitas, M. L. Garcia Rosa, A. M. Gomes [et al.]. – 2016. – Vol. 27(4). – P. 1659–1663. doi: 10.1007/s00198-015-3414-5. Epub 2015 Dec 9
International Diabetes Federation. Worldwide definition of the metabolic syndrome. Available at: http: //WWW.idf.org/web-data/docs/IDF Metasyndrome definition. pdf. Accessd, August 24,2005.
Influence of obesity on vertebral fracture prevalence and vitamin D status in postmenopausal women / A. Maghraoui, S. Sadni, A. E. Maataoui [et al.] // Nutr. Metab. (Lond). – 2015. – Vol. 14. – P. 12–44. doi: 10.1186/s12986-015-0041-2. eCollection 2015. PMID:26583038 [PubMed] PMCID: PMC4650260.
Impact of obesity on bone mass throughout adult life: Influence of gender and severity of obesity / L. Maïmoun, T. Mura, E. Leprieur [et al.] // Bone. – 2015. – Vol. 1. pii: S8756-3282(15)00421-4. doi: 10.1016/ j.bone.2015.11.020.
Official Positions of the International Society for Clinical Densiometry, Copyright ISCD, October 2007, Supersedes all prior “Official Positions” publications. http://www.iscd.org/official-positions/2015-iscd-official-positions-adult/
Papachristou D. J. Bone and high-density lipoprotein: The beginning of a beautiful friendship / D. J. Papachristou, H. C. Blair // World J. Orthop. – 2016. – Vol. 7(2). – P. 74–77. doi: 10.5312/wjo.v7.i2.74. eCollection 2016.
Serum lipid levels and bone mineral density in Greek postmenopausal women / P. Pliatsika, A. Antoniou , A. Alexandrou [et al] // Gynecol. Endocrinol. – 2012 Vol. 28(8). – P. 655–660. doi: 10.3109/09513590.2011.650766. Epub 2012 Feb 10.
Prevalent osteoporotic fractures in 622 obese and non- obese menopausal women / C. Poiana, M. Carsote, V. Radoi [et al.] // J. Med. Life. – 2015. – Vol. 8(4). – P. 462–466. PMCID: PMC4656953.
Associations of lipoproteins with bone mass in postmenopausal women / I. A. Skripnikova, E. S. Abirova, P. A. Alyasova [et al.] // Ter. Arkh. – 2016. – Vol. 88(1). – P. 82–88. - PMID:26978615
Viccica G. Role of the cholesterol biosynthetic pathway in osteoblastic differentiation / G. Viccica, E. Vignali, C. Marcocci // J. Endocrinol. Invest. – 2007. – Vol. 30(6 Suppl). – P. 8–12. PMID:17721067.
