MAIN CHARACTERISTICS OF RHYTHM DISORDERS IN PATIENTS WITH HYPERTENSION COMBINED WITH CHRONIC ISCHEMIC HEART DISEASE ON THE BACKGROUND OF COMORBIDITY WITH GASTROESOPHAGEAL REFLUX DISEASE
DOI:
https://doi.org/10.11603/1811-2471.2016.v27.i3.6773Keywords:
hypertension, chronic ischemic heart disease, gastroesophageal reflux disease, arrhythmias, AF.Abstract
SUMMARY. The aim of the study was to demonstrate the impact of GERD on during coronary heart disease as an example of analysis, quantitative and qualitative characteristics of rhythm disorders as well as the frequency and duration of ischemic episodes in patients with hypertension combined with chronic ischemic heart disease on the background of GERD. For this purpose, 107 patients were examined with hypertension combined with chronic ischemic heart disease, age 44 to 78 years. The average age of the patients was 63.4±8.94 years, including 73 (68.2 %) women and 34 (31.8 %) men. The main group consisted of 65 patients with hypertension combined with chronic ischemic heart disease on the background of GERD and 42 patients with hypertension combined with chronic ischemic heart disease without concomitant GERD, respectively, included in the control group. All the general clinical and instrumental examinations in accordance with the intended objectives of the study were carried out: as clinical, echocardiography, Holter ECG, esophagogastroduodenoscopy. The findings suggest that a significantly greater frequency of rhythm disorders like supraventricular and ventricular in patients with hypertension combined with chronic ischemic heart disease on the background of GERD. Аlso, the quantitative characteristics of arrhythmia patients with concomitant GERD is characterized by more severe rhythm disorders, that displays a large number of patients with arrhythmias higher grades. The presence of concomitant GERD in patients with hypertension combined with chronic ischemic heart disease significantly more often associated with the presence of AF. The frequency of ischemic episodes in patients with hypertension combined with chronic ischemic heart disease on the background of GERD were significantly more frequently than patients without concomitant GERD. Therefore, GERD in patients with hypertension combined with chronic ischemic heart disease is the additional factor that worsens the IHD and creates conditions to improve overall cardio-vascular risk.
References
Alekseeva O. P. Koronarnyy syndrom KH – odna yz vnepyshchevodnykh masok hastroézofahealʹnoy reflyuksnoy bolezny ? / O. P. Alekseeva, Y. V. Dolbyn // Medytsyna neotlozhnykh sostoyanyy. – 2009. – № 1. – S. 23–25.
Babak M. O. Poshyrenistʹ typovykh ta atypovykh proyaviv hastroezofahealʹnoyi refleksnoyi khvoroby / M. O. Babak // Ukrayinsʹkyy terapevtychnyy zhurnal. – 2011. – № 2 – S. 33–37.
Zharinov O. Y. Metodyka vykonannya ta interpretatsiya rezulʹtativ navantazhuvalʹnykh prob / O. Y. Zharinov, V. O. Kutsʹ, N. V. Tkhor // Zdorovʺya Ukrayiny. – 2007. – № 12/1. – S. 74–75.
Kozlova Y. V. Hastoézofahealʹnyy reflyuks y stepenʹ ézofahyta u bolʹnykh YBS: vlyyanye na pokazately repolyaryzatsyy y varyabelʹnosty serdechnoho rytma / Y. V. Kozlova, S. V. Lohynov, YU. H. Shvarts // Klynycheskaya medytsyna. – 2004. – № 9. – S. 20–34.
Kovalenko V. M. Khvoroby systemy krovoobihu yak medyko-sotsialʹna i suspilʹno-politychna problema: analitychno-statystychnyy posibnyk / V. M. Kovalenko, V. M. Kornatsʹkyy. – K. : Natsionalʹnyy naukovyy tsentr
«Instytut kardiolohiyi im. M. D. Strazhesko», 2014. – 278 s.
Hastroézofahealʹnaya reflyuksnaya boleznʹ u lyudey pozhyloho vozrasta / L. B. Lazebnyk, YU. V. Vasylʹev, A. É. Lychkova, A. A. Masharva // Klyn. heront. – 2007. – № 1. – S. 38–49.
Maev Y. V. Hastroézofahealʹnaya reflyuksnaya boleznʹ – boleznʹ KHKHI veka / Y. V. Maev // Lechashchyy vrach. – 2004. – № 4. – S. 10–14.
Ostrohlyad A. V. Pershyy dosvid vyvchennya epidemiolohiyi hastroezofahealʹnoyi reflyuksnoyi khvoroby v Ukrayini / A. V. Ostrohlyad // Suchasna hastroenterol. – 2006. – № 1. – S. 30–32.
Osoblyvosti kliniky ta spilʹni lanky patohenezu ishemichnoyi khvoroby sertsya ta hastroezofahealʹnoyi reflyuksnoyi khvoroby / O. S. Khukhlina, S. V. Virsta, I. V. Trefanenko // Klin. ta eksperyment. patolohiya. – 2011. – № 2. – S. 151–154.
Gastroesophageal Reflux Disease and Atrial Fibrillation: A Nationwide Population-Based Study / Chin-Chou H., Wan-Leong C., Jiing-Chyuan L. [et al.] // PLoS One. – 2012. – Vol. 7. – P. 1932–6203.
Is there a link between gastroesophageal reflux disease and atrial fibrillation? / J. S. Kunz, B. Hemann, J. Edvin Atwood [et al.] // Clin. Cardiol. – 2009. – Vol. 32 (10). – R. 584–587.
Richter J. The refractory GERD patient / J. Richter // World Gastroenterol. News. – 2007. – Vol. 12. – P. 11–13.
Atrial fibrillation in patients with gastroesophagel reflux disease: A comprehensive review / C. Roman, S. Bruley des Varannes, L. Muresan [et al.] // World Journal of Gastroenterology. – 2014. – Vol. 20. – P. 9592–9599.
