Assessment of potentialities of neuroprotective action of Canephron in patients with gout nephropathy
DOI:
https://doi.org/10.11603/1811-2471.2016.v25.i1.6022Abstract
SUMMARY. The risk of chronic kidney failure increases in 3–10 times with the steady increasing of uric acid level in
the blood. It is known that the protein fractions are closely correlated with the level of uric acid. Microalbuminuria and
microglobulinuria are predictors of kidney damage. The study involved 50 patients with gout who had never received
preventive treatment of gouty nephropathy. We chose Canephron N (Bionorica, Neumarkt, Germany) as a combined
phytodrug with neuroprotective effect. All studied patients were men with obesity. According to standard examination
kidney damage hadn’t been found, but laboratory tests on microproteinuria showed that the vast majority of patients
had signs of subclinical gouty nephropathy. Canephron N in complex gout treatment helps to decrease uric acid level in
the blood and increase its excretion.
Key words : gout, chronic kidney disease, hyperuricemia, Canephron N, microalbuminuria, microglobulinuria.
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