Intensity of lipid intensity of peroxidation in rabbits with chemical burns of the cornea against merkazolil-induced hypothyroidism
DOI:
https://doi.org/10.11603/1811-2471.2015.v23.i2-3.5278Abstract
Summary . The article analyzes the results of a study of lipid peroxidation intensity of blood and intraocular fluid of
the anterior chamber of rabbit corneal chemical burns caused by the imposition of filter paper moistened with 1 N NaOH
against the backdrop previously simulated merkazolil-induced hypothyroidism. Found that in animals with chemical burns
to the cornea background hypothyroidism compared with evtyroyidnymy animals detected a significant reduction of
reactive oxygen species production by mononuclear white blood cells, inhibition of lipid peroxidation intensity, resulting
in reducing the concentration of lipid hydroperoxides, TBA-reactive products and Schiff bases in blood and intraocular
fluid of the anterior chamber of the eye. It is concluded that the conditions associated deficiency of thyroid hormones is
a suppression of free radical processes as a place of destruction, and the body as a whole.
Key words : burn the cornea, hypothyroidism, lipid peroxidation
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