Clinical and epidemiological aspects of endometrial hyperplasia in perimenopausal women

Authors

  • P. R. Selskiy I. Ya. Gorbachevsky Ternopil State Medical University, Ternopil, Ukraine
  • A. F. Slyva I. Ya. Gorbachevsky Ternopil State Medical University, Ternopil, Ukraine
  • V. V. Slyva I. Ya. Gorbachevsky Ternopil State Medical University, Ternopil, Ukraine

DOI:

https://doi.org/10.11603/1811-2471.2015.v23.i2-3.5277

Abstract

SUMMARY. To improve the efficiency of diagnosis of endometrial hyperplastic processes in perimenopausal women
was conducted a retrospective analysis of 52 cards inpatient women who were treated at gynecological departments
of Ternopol region. According to the histopathological finding 1st group included 28 women with simple endometrial
hyperplasia; 2nd group – 24 women with complex endometrial hyperplasia. Comparison group consisted of 12 somatically
healthy women. The average age of patients of group 1 – (47,0±1,0) years, group 2 – (56,0±1,5) years. In order depth
analysis parameters neural network clustering applied. Established that the risk factors for hyperplastic processes of
endometrium in women of perimenopausal period include disadvantaged socio-economic factors: residence in rural
areas, difficult working conditions, bad habits and burdened obstetric and gynecological history, 3 or more pregnancies,
a large number (4 and more ) obstetrical interventions, use of intrauterine contraception. In women with different types
of endometrial hyperplasia the course of the climacteric syndrome was moderate and severe with neuro-vegatative,
endocrine-metabolic, and psycho-emotional manifestations. Among the comorbid conditions often seen dyshormonal
pathology of breast and hepatobiliary tract disorders.
Key words : endometrial hyperplasia, menopausal syndrome, perimenopausal age, dysfunctional uterine bleeding,
comorbid diseases, neural network clustering.

References

Vykhlyaeva E. M. Hyperplastycheskye protsessy éndometryya / E. M. Vykhlyaeva, B. Y. Zheleznoe, V. N. Zaporo-

zhan // Rukovodstvo po éndokrynnoy hynekolohyy. – M. :

MYA, 2002. – S. 603–710.

Volkova N. Y. Zdorovʹe zhenshchyn v perymenopau-

ze. Teoryya y praktyka / N. Y. Volkova // Zhur. akush. y

zhen. bolezney. – 2004. – Vyp. 2. – T. LII. – S. 54–59.

Kuznetsov Y. V. Hyperplastycheskye protses-

sy éndometryya / Y. V. Kuznetsov. – M. : Medytsyna,

– 48 s.

Klymakterycheskyy peryod y menopauza // Ra-

tsyonalʹnaya farmakoterapyya v akusherstve y hyneko-

lohyy : rukovodstvo dlya prakt. vr. – M., 2005. – Hl. 48. –

S. 593–603.

Menopauza y svyazannye s ney rasstroystva /

F. Kapp [y dr.] // Akusherstvo, hynekolohyya y zdorovʹe

zhenshchyny : per. s anhl. M., 2005. – Razd. 12. – S. 156–163.

Chebotnykova T. V. Klynycheskye y metaboly-

cheskye proyavlenyya klymakterycheskoho syndroma /

T. V. Chebotnykova, H. A. Melʹnychenko, E.N. Andreeva //

Probl. reproduktsyy. – 2004. – № 2. – S. 69–77.

Metabolic and vascular effect of progestins in postmenopausal

women: implications for cardioprotection /

G. M. C. Rosano, C. Vitale, A. Silvestri, M. Fini // Maturitas. –

– Vol. 46 (Suppl. 1). – P. 17–29.

Shepherd A. J. Second-Order Methods for Neural

Networks : Fast and Reliable Training Methods for Multi-

Layer Perceptrons / A. J. Shepherd. – London : Springer,

– 342 p.

Martsenyuk V. P. Neyromerezheve prohnozuvannya

skladannya studentamy-medykamy litsenziynoho intehro-

vanoho ispytu “Krok 1” na osnovi rezulʹtativ potochnoyi

uspishnosti ta semestrovoho kompleksnoho testovoho

ispytu / V. P. Martsenyuk, A. V. Semenetsʹ, O. O. Stakhan-

sʹka // Medychna informatyka ta inzheneriya. – 2010. –

№ 2. – C. 57–62.

Published

2015-11-16

How to Cite

Selskiy, P. R., Slyva, A. F., & Slyva, V. V. (2015). Clinical and epidemiological aspects of endometrial hyperplasia in perimenopausal women. Achievements of Clinical and Experimental Medicine, 23(2-3). https://doi.org/10.11603/1811-2471.2015.v23.i2-3.5277

Issue

Section

Оригінальні дослідження