The impact of structural and functional state of the heart on the development of cognitive impairment in patients with hypertensio
DOI:
https://doi.org/10.11603/1811-2471.2015.v23.i2-3.5275Abstract
Summary. In 35 patients with hypertension the influence of structural and functional state of the heart on the state of cognitive functions was examined. Assessment of cognitive status was performed using short scale assessment of mental status (MMSE) and Montreal scale (MOCA). Sustainabilityof attention and speed of sensorimotor reactions were investigated using the tables of Schulte. The quality of life of patients was evaluated for physical and mental component using a questionnaire SF-12. All patients underwent echocardiographic examination with assessment of interventricular septum thickness, posterior wall thickness of the left ventricle, end-diastolic size of the left ventricle, the size of the aorta and left atrium, right ventricular dimensions and left ventricular ejection fraction. It was found that in patients with hypertension reduction in left ventricular ejection fraction determines the severity of cognitive impairment and promotes worsening of the quality of life in these patients. The development of cognitive impairment also depends on the size of the left atrium, interventricular septum thickness and posterior wall of the left ventricle and left ventricle end-diastolic size. There was no significant effect of the diameter of aorta and the right ventricle size on the cognitive status.
Key words: hypertension, cognitive function, quality of life, structural and functional heart condition.
References
Vasserman L. Y. Metody neyropsykholohycheskoy dyahnostyky : Praktycheskoe rukovodstvo / L. Y. Vasserman, S. A. Dorofeeva, YA. A. Meerson. – SPb. : Stroylespechatʹ, 1997. – 34 s.
Vsemyrnaya orhanyzatsyya zdravookhranenyya (2011) Plan deystvyy po Evropeyskoy stratehyy profylaktyky y borʹby s neynfektsyonnymy zabolevanyyamy, 2012–2016 hh. Evropeyskyy rehyonalʹnyy komytet VOZ. Shestʹdesyat pervaya sessyya. – Azerbaydzhan, Baku, 12–15 sentyabrya. – 5 s.
Dzheyms F. Tul. Sosudystye zabolevanyya holovnoho moz·ha / Dzheyms F. Tul. – M. : HÉOTAR-Medya, 2007. – 608 s.
Evstyhneev V. V. Kohnytyvnye narushenyya v nevrolohycheskoy praktyke / V. V. Evstyhneev. – Mynsk : Belprynt, 2009. – S. 45–52.
Zakharov V. V. Narushenyya pamyaty / V. V. Zakharov, N. N. Yakhno. – M. : HeotarMed, 2003. – 150 s.
Zakharov V. V. Kohnytyvnye rasstroystva v pozhylom y starcheskom vozraste : metod. posobye dlya vrachey / V. V. Zakharov, N. N. Yakhno. – M., 2005. – 71 s.
Zakharov V. V. Vserossyyskaya prohramma yssledovanyy épydemyolohyy y terapyy kohnytyvnykh rasstroystv v pozhylom vozraste («Prometey») / V. V. Zakharov // Nevroloh. zhurn. – 2006. – T. 11. – S. 27–32.
Zvereva Z. F. Klynycheskye y neyrofyzyolohycheskye pokazately u bolʹnykh s dystsyrkulyatornoy éntsefalopatyey / Z. F. Zvereva // Zhurnal nevrolohyy y psykhyatryy ym. S. S. Korsakova. – 2010. – № 2. – S. 15–18.
Klinichni rekomendatsiyi z arterialʹnoyi hipertenziyi Yevropeysʹkoho tovarystva hipertenziyi (ESH) ta Yevropeysʹkoho tovarystva kardiolohiv (ESC) 2013 roku. – K., 2014.− 192 s.
Lahoda O. V. Lechenye narushenyy pamyaty u bolʹnykh s sosudystymy zabolevanyyamy holovnoho moz·ha / O. V. Lahoda // Russkyy medytsynskyy zhurnal. Nevrolohyya. Psykhyatryya. – 2004. – № 22. – S. 12–14.
Alhorytm prohnozyrovanyya razvytyya kohnytyvnykh narushenyy u bolʹnykh s arteryalʹnoy hypertenzyey y aterosklerozom koronarnykh y tserebralʹnykh arteryy / N. K. Murashko, T. P. Parnykoza, H. N. Chupryna, R. V. Sulyk [y dr.] // Metodycheskye rekomendatsyy. – Kyev, 2014. – 40 s.
Stadnik S. M. Prohnostychni kryteriyi prohresuvannya kohnityvnykh rozladiv u patsiyentiv z dystsyrkulyatornoyu entsefalopatiyeyu na foni atrioventrykulyarnoyi blokady / S. M. Stadnik // Liky Ukrayiny. – 2014. – № 4 (21). – S. 10–14.
Starchyna YU. A. Kohnytyvnye funktsyy y émotsyonalʹnoe sostoyanye bolʹnykh, perenesshykh ynsulʹt, na fone antyhypertenzyvnoy terapyy / YU. A. Starchyna, V. A. Parfenov, Y. E. Chazova // Zhurn. nevrol. y psykhyat. ym. S. S. Korsakova. Ynsulʹt. – 2005. –Vyp. 15. – S. 39–44.
Praktycheskaya kardyonevrolohyya / Z. A. Suslyna, A. V. Fonyakyn [y dr.] // YMA-PRESS, 2010. – 304 c.
Prevalence of DiagnosedAtrial Fibrillation in Adults / Alan S. Go, Elaine M. Hylek, Kathleen A. Phillips [et al.] // JAMA. – 2001. – Vol. 285, № 7. – P. 2370–2375.
Boss Ch. J. Is atrial fibrillation an inflammatory disorders? / Ch. J. Boss, R. A. Anderson, G.Y.H. Lip // Eur. Heart. J. – 2006. – Vol. 27. – R. 136–149.
The role of blood pressure in cognitiveimpairment in an elderly population / F. Cacciatore, P. Abete, N. Ferrara [et al.] // J. of Hypertension. – 2002. – Vol. 15. – P. 0135–0142.
Engelmann M. D. M. Inflammation in the genesis of atrial fibrillation / M. D. M. Engelmann, J. N. Svedsen // Eur. Heart. J. – 2005. – Vol. 20 (26). – R. 2083–2092.
Jelic V. Clinical trials in mild cognitive impairment: lessons for the future / V. Jelic, M. Kivipelto, V. Winblad // J. Neurology Neurosurgery Psychiatry. – 2006. –Vol. 77. – 892 p.
Folstein M. F. Mini Mental State: A practical method for grading the cognitive state of patients for the clinician / M. F. Folstein, S. E. Folstein, P. R. McHugh // Journal of Psychiatric Research. – 1975. – № 12 (3). – R. 189–198.
Nasreddine Ziad S., Phillips Natalie A., Bédirian Valérie, Charbonneau Simon, Whitehead Victor, Collin Isabelle, Cummings Jeffrey L., Chertkow Howard. The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. – 2005. – Vol. 53(4). – P. 695–699.
Pullicino P. M. Cognitive Impairment in congestive heart failure / R. M. Pullicino, J. Hart // Neurology. – 2001. – Vol. 57. – R. 1945–1946.
Skoog I. Clinical trials for primary prevention in dementia / I. Skoog, D. Gustafson // Dementia therapeutic research. – 2006. – P. 189–212.
Ware J. E. A 12-Item Short-Form Health Survey: Construction of scales and preliminary tests of reliability and validity / J. E. Ware, M. Kosinski, S. D. Keller // Medical Care. – 1996. – Vol. 34 (3).– P. 220–233.
