Disturbance of the indicators humoral immunity and circulating immune complexes in the dynamic of early period after skeletal, craniocerebral and combined traumas
DOI:
https://doi.org/10.11603/1811-2471.2015.v23.i2-3.5245Abstract
Summary. In the early period after application of skeleton, craniocerebra and combined traumas (1–7 days) in serum significantly increases the content of Ig A, G, circulating immune complexes compared to the control group. After 3 days this figure rises to a maximum and remain at the same level during 7 days. The content of Ig A and circulating immune complexes in serum significantly greater after the combined trauma after 7 days post-traumatic period. After 3–7 days after applying injuries in serum significantly reduced the content of Ig M. Dynamics of content changes of Ig G and M doesn't depend from the localization of mechanical traumas.
Key words: skeletal, craniocerebral, combined trauma, immunoglobulins, circulating immune complexes.
References
Dzyuba D. A. Pokazately aktyvatsyy apoptoza v techenyy polytravmy tyazheloy stepeny / D. A. Dzyuba, Y. R. Malysh, L. V. Z·hrzheblovskaya // Ukrayinsʹkyy zhurnal ekstremalʹnoyi medytsyny imeni H. O. Mozhayeva. – 2008. – T. 9, № 1. – S. 53–58.
Elʹskyy V. N. Modelyrovanye cherepno-moz·hovoy travmy / V. N. Elʹskyy, S. V. Zyablytsev. – Donetsk : Yzd-vo “Novyy myr”, 2008. – 140 s.
Kazmirchuk V. YE. Klinichna imunolohiya i alerholohiya / V. YE. Kazmirchuk, L. V. Kovalʹchuk. – Vinnytsya : Nova knyha. – 2006. – S. 267–275.
Kozak D. V. Dynamika vmistu tsyrkulyuyuchykh imunnykh kompleksiv ta imunohlobuliniv u vidpovidʹ na politravmu v eksperymenti / D. V. Kozak // Klinichna khirurhiya. – 2013. – № 12 (852). – S. 76–78.
Kozak D. V. Vplyv karbatsetamu na dynamiku pokaznykiv tsytolizu ta vmist tsyrkulyuyuchykh imunnykh kompleksiv v umovakh politravmy / D. V. Kozak // Visnyk naukovykh doslidzhenʹ. – 2014. – № 2 (75). – S. 80–82.
Dynamyka kontsentratsyy ymmunohlobulynov klassov M, G, A v syvorotke krovy u patsyentov s bronkholehochnymy oslozhnenyyamy v ostrom y rannem peryodakh pozvonochno-spynnomoz·hovoy travmy / E. A. Konyuchenko, V. YU. Ulʹyanov, D. M. Puchynʹyan, E. V. Karyakyna // Saratovskyy nauchno-medytsynskyy zhurnal. – 2010. – T. 6, № 4. – S. 841–844.
Malysh Y. R. Kharakterystyka yzmenenyy v kletochnom y humoralʹnom ymmunytete u postradavshykh s syndromom polyorhannoy nedostatochnosty vsledstvye tyazheloy polytravmy / Y. R. Malysh // Ukrayinsʹkyy medychnyy alʹmanakh. – 2005. – T. 8, № 5. – S. 98–101.
Marchenko M. I. Tsyrkulyuyuchi imunni kompleksy v diahnostytsi autoimunnykh zakhvoryuvanʹ / M. I. Marchenko // Student·sʹkyy nukovyy zhurnal. – 2008. – rezhym dostupu : http://s-journal.cdu.edu.ua/base/2008/v2/v2pp109-110.pdf
Otsenka vlyyanyya faktorov okruzhayushchey stredy na ymmunolohycheskuyu reaktyvnostʹ orhanyzma : metodycheskye rekomendatsyy / NYY obshchey y kommunalʹnoy hyhyeni ym. A. N. Marzeeva. – K., 1988. – 23 s.
Pat. 81107 Ukrayina, MPK G 09 V 23/28. Sposib modelyuvannya politravmy / Levchuk R. D., Mykhaylyuk I. A., Merlyev D. I. ; zayavnyk i patentovlasnyk Derzhavnyy vyshchyy navchalʹnyy zaklad “Ternopilʹsʹkyy derzhavnyy medychnyy universytet imeni I. YA. Horbachevsʹkoho MOZ UKrayiny”. – № u 201213575 ; zayavl. 27.11.12 ; opubl. 25.06.13, Byul. 12.
Roshchin H. H. Bahatofaktornyy analiz letalʹnosti pry poyednaniy travmi orhaniv cherevnoyi porozhnyny / H. H. Roshchin, V. I. Ivanov, V. O. Krylyuk // Klinichna khirurhiya. – K. : TOV "Liha-Inform" – 2013. – № 4. – S. 40–44.