ASPECTS OF THE ORIGIN AND DEVELOPMENT OF NOSOCOMIAL INFECTIONS IN PATIENTS WITH PANCREAS LESIONS
(LITERATURE REVIEW)
DOI:
https://doi.org/10.11603/1811-2471.2025.v.i3.15546Keywords:
nosocomial infection, pancreas, acute pancreatitis, chronic pancreatitis, peripheral arteries comorbidityAbstract
SUMMARY. Traditionally, hospital-acquired infections include those infectious diseases that develop in a medical institution 48 or more hours after a patient’s hospitalization during treatment or during discharge. Today, there is an increase in these pathologies in various countries, regardless of their level of economic development. The prevalence of hospital-acquired infections is 5.1–11.6 % for low-income countries and 5.7–19.7 % for middle-income countries.
The aim – to analyze the scientific literature on the frequency, etiology, pathogenesis, features of the clinical course, and possibilities for preventing the occurrence of nosocomial infections in pancreatic diseases.
Main content. The most vulnerable category is the category of patients who are inpatients, as they have a more severe clinical condition (which necessitated their hospitalization), and they have a higher risk of contamination by representatives of multi-resistant hospital flora. Acute and chronic pancreatitis are common somatic pathologies that worsen the nutritional status of the patient. This makes it advisable to consider the mutually aggravating elements of the pathogenesis of nosocomial infections in patients with pancreatic lesions.
Conclusions. Structural and functional disorders of the pancreas during its acute or chronic inflammation, as well as the influence of factors contributing to its development, explain the predisposition of this category of hospitalized patients to the occurrence of nosocomial infections, which requires further optimization of treatment and prevention methods for these pathological conditions.
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