FEATURES OF VAGINAL MICROBIOTA IN WOMEN OF REPRODUCTIVE AGE
DOI:
https://doi.org/10.11603/1811-2471.2023.v.i3.13899Keywords:
bacterial vaginosis, dysbiosis, vaginal thrush, aerobic vaginitis, microorganisms, vaginal microbiotaAbstract
SUMMARY. Decreased lactobacilli count on the mucous membrane of the vagina and cervix leads to changes in the species composition of vaginal microbiota and is accompanied by inflammatory processes in the female genital organs.
The aim – to investigate the species spectrum of the vaginal microbiome in women of reproductive age without signs of infectious-inflammatory processes, as well as in the presence of inflammatory processes in comparison with normocenosis.
Material and Methods. We examined 75 female patients aged 20–45 with various disorders of vaginal microbiota. The examined patients were divided into three age groups: the first group (20 women) – 20–30 years old, the second group (30 women) – 30–40 years old, the third group (25 women) – 35–45 years old, and a control group (10 women) with a normal vaginal microbiota. The laboratory investigations included bacterioscopic, bacteriological, and cultural methods for studying the species composition (CFU/mL) and microbial associations in different nosological forms according to Kopeloff's modification.
Results. The most frequently identified microorganisms in the vaginal microbiota of the examined women: Gardnerella vaginalis, Atopobium vaginae, Mobiluncus spp., Prevotella spp., Streptococcus spp., Bacteroides spp., Enterococcus spp., Candida albicans, Fusobacterium spp., Peptostreptococcus spp., Eubacterium spp., and Veillonella spp., with varying amount CFU/mL.
Conclusions. Microbiological examination of the vaginal microbiota in women allowed for the detection of disturbances in the species composition of microorganisms and the establishment of their nosological form.
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