THERMOGRAPHIC EVALUATION OF GOUT COURSE IN COMBINATION WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND TREATMENT

Authors

  • U. O. Mudra I. Horbachevsky Ternopil National Medical University
  • S. M. Andreychyn I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.11603/1811-2471.2023.v.i1.13715

Keywords:

gout, thermography, non-alcoholic fatty liver disease, enterosorbent

Abstract

Summary. Gout is an urgent problem today, as its prevalence has doubled in recent decades. Disorders of thermoregulation and regional blood flow are an important clinical and pathogenetic manifestation of gout, which can be assessed by recording infrared radiation.

The aim – to evaluate the thermographic semiotics of gout and thermographic indicators of its course in concomitant non-alcoholic fatty liver disease (NAFLD) and the effectiveness of their treatment.

Material and Methods. 74 male gout patients were examined. They were divided into 2 groups. Group I included 38 patients with gout without liver damage, group II – 36 patients with NAFLD. Both groups were divided into subgroups: IA and IIA who received basic therapy, IB and IIB who additionally received carbon enterosorbent. The control group consisted of 20 healthy individuals. Thermographic study was performed using a thermal imager ULIRvision TI 120.

Results. The temperature gradient of symmetrical areas in healthy individuals (control group) was (0.37±0.04) °C. In all patients before treatment thermograms shows a zone of intense hyperthermia with clear contours, which exceeded the size of the visible hyperemia in the affected joint. The temperature gradient in patients with gout without liver damage was (3.99±0.17) °C, and in patients with concomitant NAFLD – (4.41±0.14) °C (p>0.05). On thermograms after treatment in most patients of both groups there was still a zone of hyperthermia. It was smaller in area and intensity, the clarity of the contours was lost. Therapy results were significantly better in patients receiving basic therapy with enterosorbent, but they still did not meet the norm (p<0.05).

Conclusion. Thermography makes it possible to determine the change in local temperature of the affected joints at gout during exacerbation, to establish the location and prevalence of the pathological process and to assess the effectiveness of treatment.

References

Kozhevnikova, I.S., Pankov, M.N., Gribanov, A.V., Startseva, L.F., & Ermoshina, N.A. (2017). The use of infrared thermography in modern medicine (Literature review). Human Ecology, 15(2), 39-46. DOI: https://doi.org/10.33396/1728-0869-2017-2-39-46

Olijnyk, G.A., Kremen, V.O., Gryazin, O.Ye., & Tymchenko, O.K. (2018). Teplove vyprominyuvannya ta teplovizijni doslidzhennya v medycyni [Thermal radiation and thermal imaging studies in medicine]. Aktualni problemy suchasnoyi medycyny: Visnyk Ukrayinskoyi medychnoyi stomatologichnoyi akademiyi – Topical Problems of Modern Medicine. Bulletin of the Ukrainian Medical Dental Academy, 18(2), 266-272 [in Ukrainian].

Ring, F. (2016). The Herschel heritage to medical thermography. Journal of Imaging, 2(2), 13. DOI: 10.3390/jimaging2020013. DOI: https://doi.org/10.3390/jimaging2020013

Olaru, A. (2017). Infrared thermographic evaluation of patients with metastatic vertebral fractures after combined minimal invasive surgical treatment. The Moldovan Medical Journal, 60(2), 22-25. DOI: 10.5281/zenodo.1051067.

Ostafijchuk, D.I., Shajko–Shajkovskyj, O.G., Rozhnov, O.O., & Bilov, M.Ye. (2019). Termografiya v medycyni–zagalni pryncypy [Тhermography in medicine – general principles]. Problemy bezperervnoyi medychnoyi osvity ta nauky – Problems of Continuous Medical Education and Science, 1(33), 68-74 [in Ukrainian]. DOI: https://doi.org/10.31071/promedosvity2019.01.068

Jasti, N., Bista, S., Bhargav, H., Sinha, S., Gupta, S., Chaturvedi, S. K., & Gangadhar, B.N. (2019). Medical applications of Infrared thermography: A narrative review. Journal of Stem Cells, 14(1), 35-53.

Lahiri, B.B., Bagavathiappan, S., Jayakumar, T., & Philip, J. (2012). Medical applications of infrared thermography: a review. Infrared Physics & Technology, 55(4), 221-235. DOI: https://doi.org/10.1016/j.infrared.2012.03.007

Andrejchyn, M.A., & Kopcha, Yu.V. (2016). Dystancijna termografiya ta yiyi znachennya dlya diagnostyky gostrogo tonzylitu [Distance thermography and it value at diagnostics of acute tonsillitis]. Infektsiyni khvoroby – Infectious Diseases, 3(85), 82-88. [in Ukrainian].

Pauk, J., Wasilewska, A., & Ihnatouski, M. (2019). Infrared thermography sensor for disease activity detection in rheumatoid arthritis patients. Sensors, 19(16), 3444. DOI: https://doi.org/10.3390/s19163444

Jin, C., Yang, Y., Xue, Z.J., Liu, K.M., & Liu, J. (2013). Automated analysis method for screening knee osteoarthritis using medical infrared thermography. Journal of Medical and Biological Engineering, 33(5), 471-477. DOI: https://doi.org/10.5405/jmbe.1054

Bardin, T., & Richette, P. (2017). Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment options. BMC Medicine, 15(1), 1-10. DOI: https://doi.org/10.1186/s12916-017-0890-9

Mudra, U., Andreychyn, S., Hanberher, I., & Korylchuk, N. (2020). Indicators of gout interlaykins and thermography of joints on the background of enterosorbtion therapy. Georgian Medical News, 6(303), 97-102.

European Association for the Study of The Liver, & European Association for the Study of Diabetes (EASD-EASL-EASD-EASO). (2016). Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease. Obesity Facts, 9(2), 65-90. DOI: https://doi.org/10.1159/000443344

Svinciczkyj, A.S., Kozak, N.P., & Ostafijchuk, A.S. (2011). Osoblyvosti perebigu podagry na foni metabolichnogo syndrome [Pecularities of gouts’ course in association with the metabolic syndrome]. Ukrayinskyj revmatologichnyj zhurnal – Ukrainian Rheumatology Journal, 46(4), 1-3 [in Ukrainian].

Andrejchyn, M.A. (1990). Teplobachennya v medycyni [Thermal vision in medicine]. Kyiv: Medytsyna [in Ukrainian].

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Published

2023-03-30

How to Cite

Mudra, U. O., & Andreychyn, S. M. (2023). THERMOGRAPHIC EVALUATION OF GOUT COURSE IN COMBINATION WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND TREATMENT . Achievements of Clinical and Experimental Medicine, (1), 21–26. https://doi.org/10.11603/1811-2471.2023.v.i1.13715

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Оригінальні дослідження