QUALITY OF LIFE AND FUNCTIONAL STATUS OF PATIENTS WITH STABLE ISCHEMIC HEART DISEASE COMBINED WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
DOI:
https://doi.org/10.11603/1811-2471.2022.v.i3.13289Keywords:
ischemic heart disease, chronic obstructive pulmonary disease, quality of life, 6-minute walk test, comorbidityAbstract
SUMMARY. The aim – to estimate the components of quality of life (QoL) and their relationship with the functional status of patients with stable ischemic heart disease (IHD) combined with chronic obstructive pulmonary disease (COPD).
Materials and Methods. The main group (group 1) included 108 men with stable IHD and COPD. As comparison groups were examined 30 men with stable IHD (group 2) and 30 men with COPD (group 3). The control group included 30 men without IHD and respiratory diseases. All groups were comparable in age. QoL was assessed using non-specific questionnaire "The 36‑Item Short Form Health Survey" (SF-36), in patients of groups 1 and 3 additionally using specific respiratory questionnaire of St. George’s Hospital (SGRQ). The exercise tolerance was assessed using a cardiopulmonary test, which included a 6-minute walking distance (6MWT), pulsoxymetry with calculation of the level of desaturation, recording of electrocardiogram and blood pressure before and after exercise.
Results. According to the SF-36 questionnaire, patients of group 1 had a significant decrease in QoL related to physical and social functioning, role limitation, general health assessment, vital activity and mental health compared to group 2 and 3. Correlations between indicators of QoL and clinical and functional features of COPD were revealed, which indicates that QoL of patients with IHD is burdened by comorbid COPD. Patients of group 1 had a significantly shorter 6MWT distance and a significantly higher level of desaturation compared to groups 2 and 3. The cardiopulmonary test indicators had correlations with domains of the physical and mental components of QoL.
Conclusions. Patients with stable IHD combined with COPD have decreased physical and mental components of QoL compared to patients with isolated IHD and COPD. Decreased exercise tolerance in these patients is associated with worse indicators of the physical and certain domains of the mental component of QoL.
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