CHANGES IN THE QUANTITY AND QUALITATIVE PROPERTIES OF ORAL FLUID IN CHILDREN WITH CHRONIC ERYTHEMATATIC GASTRITIS WITH PRESERVED ACID-FORMING IN THE PERIOD OF EXACERBATION
DOI:
https://doi.org/10.11603/1811-2471.2021.v.i4.12814Keywords:
children, oral fluid, gastritisAbstract
SUMMARY. Data from basic and periodical scientific journals indicate that there are close correlations between functional and organic changes in different parts of the gastrointestinal tract, including the oral cavity, which is its initial part.
The aim – to study changes in the quantity and quality of oral fluid in children with chronic erythematous gastritis with preserved acid-forming function during exacerbation.
Material and Method. 27 children aged 12 to 15 years with the corresponding nosological form of the disease were examined. The non-stimulated fraction of oral fluid was used to determine pH, optical density, viscosity, α-amylase activity, medium weight molecules, sialic acid, and total protein at the time of treatment and at the end of treatment.
Results. It was found that with exacerbation of chronic erythematous gastritis with preserved acid-forming function there is a decrease in salivation rate of 1.4, and the concentration of hydrogen ions in oral fluid decreased by 1.2, and α-amylase activity by 1.4 times. This was accompanied by an increase in the average weight of molecules and sialic acids in 1.4, and total protein in 1.7 times, respectively. This increased its optical density by 1.5 times and its viscosity by 1.8 times.
Conclusions. The above components of the oral fluid, which maintain the oral homeostasis, can be successfully used as additional diagnostic and prognostic criteria for various nosological forms of diseases of the gastrointestinal tract.
References
Romanenko, Ye.G. (2014). Pokazateli sostoyaniya tkaney parodonta u detey s razlichnymi kliniko-morfologicheskimi formami khronicheskogo gastrita i duodenita [Indicators of the state of periodontal tissues in children with various clinical and morphological forms of chronic gastritis and duodenitis] Stomatologiya. Rossiya – Dentistry. Russia, 1, 140-142 [in Russian].
Stepanov, Yu.M. (2019.). Khvoroby orhaniv travlennya – aktualna problema klinichnoyi medytsyny [Digestive diseases are an urgent problem of clinical medicine]. Hastroenterolohiya – Gastroenterology, 53(1), 1-6 [in Ukrainian].
Tkachenko, P.I. (2020). Premorbidnyy fon pry hostrykh zapalnykh protsesakh shchelepno-lytsevoyi dilyanky v ditey [Premorbid background in acute inflammatory processes of the maxillofacial area in children]. Ukrayinskyy stomatolohichnyy almanakh – Ukrainian Dental Almanac, 3, 15-20 [in Ukrainian].
Popelo, Yu.V., Tkachenko, P.I., & Lokhmatova, N.M. (2021). Periodontal response to cytostatic drugs in children. Wiadomosci Lekarskie, LXXIV(6), 1322-1325.
Kopytov, A.A. (2018). Problema sochetannoy patolohyy polosty rta y orhanov pyshchevarenyya u podrostkov [The problem of combined pathology of the oral cavity and digestive organs in adolescents]. Aktualnye problemy medytsyny – Actual Problems of Medicine, 2, 220-227 [in Ukrainian].
Tkachenko, P.I. (2017). Reaktsiya pryvushnykh zaloz i bukalnoho epiteliyu u ditey zi zloyakisnymy pukhlynamy cherevnoyi porozhnyny na tli otrymannya khimioterapiyi [Reaction of parotid glands and buccal epithelium in children with malignant tumors of the abdominal cavity on the background of receiving chemotherapy]. Svit medytsyny ta biolohiyi –World of Medicine and Biology ,1(59), 83-86 [in Ukrainian].
Klitynska, O.V. (2014). Suchasni pohlyady na vplyv okremykh predstavnykiv mikroflory na rozvytok stomatolohichnykh zakhvoryuvan ta urazhen shlunkovo-kyshkovoho traktu [Modern views on the influence of individual representatives of the microflora on the development of dental diseases and lesions of the gastrointestinal tract]. Molodyy vchenyy – Young Scientist, 11, 217-220 [in Ukrainian].
Krupey, V.Ya. (2014). Stan nespetsyfichnoyi rezystentnosti porozhnyny rota v ditey, yaki mayut kariyes i khronichnyy kataralnyy hinhivit na tli zakhvoryuvan shlunkovo-kyshkovoho traktu, u dynamitsi likuvannya. [The state of nonspecific resistance of the oral cavity in children with caries and chronic catarrhal gingivitis on the background of diseases of the gastrointestinal tract, in the dynamics of treatment]. Sovremennaya stomatolohyya – Modern Dentistry, 1, 70-73 [in Ukrainian].
Tkachenko, P.I. (2015). Korektsiya shvydkosti salivatsiyi ta mineralizuyuchoho potentsialu rotovoyi ridyny v ditey zi zloyakisnymy pukhlynamy myakykh tkanyn, yaki otrymuyut polikhimioterapiyu [Correction of salivation rate and mineralizing potential of oral fluid in children with malignant soft tissue tumors receiving polychemotherapy]. Ukrayinskyy stomatolohichnyy almanakh – Ukrainian Dental Almanac, 5, 65-70 [in Ukrainian].
Matsko, N.V. (2013). Khelikobakterna infektsiya u rozvytku i perebihu zakhvoryuvan tkanyn parodonta pry hastroduodenalnykh vyrazkakh. [Helicobacter pylori infection in the development and course of periodontal disease in gastroduodenal ulcers]. Zdobutky klinichnoyi i eksperymentalnoyi medytsyny – Achievements of Clinical and Experimental Medicine, 2, 137-145 [in Ukrainian].
Sheshukova, O.V. (2020). Stomatolohichnyy status u ditey z khronichnym hastroduodenitom [Dental status in children with chronic gastroduodenitis]. Visnyk problem biolohiyi i medytsyny – Bulletin of Problems of Biology and Medicine, 3(157), 370-373 [in Ukrainian].
Popelo, Yu.V., Tkachenko, P.I., & Bilokon, S.O. (2019). Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors. Wiadomosci Lekarskie, LXXII, 5(II), 978-982.
Bauman, S.S. (2020). Poshyrenist khronichnoho kataralnoho hinhivitu u ditey riznoho viku z hastroduodenitom [Prevalence of chronic catarrhal gingivitis in children of different ages with gastroduodenitis]. Visnyk problem biolohiyi i medytsyny – Bulletin of Problems of Biology and Medicine, 1(155), 17-20 [in Ukrainian].
Berkalo, L.V., Bobovych, O.V., & Bobrova, N.O. (2003). Metody klinichnykh ta eksperymentalnykh doslidzhen v medytsyni [Methods of clinical and experimental research in medicine]. Poltava: Polimet [in Ukrainian].
Habryélyan, N.Y. (1983). Opyt yspolzovanyya pokazatelya srednykh molekul v krovy dlya dyahnostyky nefrolohycheskykh zabolevanyy u detey [Experience of using the index of medium molecules in the blood for the diagnosis of nephrological diseases in children]. Laboratornoe delo – Laboratory Work, 3, 138-140 [in Russian].
Romanenko, E.H. (2013). Metodyka opredelenyya syalovoy kysloty v slyune [Methods for determining sialic acid in saliva]. Svit biolohiyi ta medytsyny – World of Biology and Medicine,1(36), 139-142 [in Russian].
Kamyshnikov, V.S. (2009). Spravochnik po kliniko-biokhimicheskim issledovaniyam i laboratornoy diagnostike [Reference book on clinical and biochemical research and laboratory diagnostics]. Moscow: Medpressinform [in Russian].
Vukolov, E.A. (2008). Osnovy statisticheskogo analiza. Praktikum po statisticheskim metodam i issledovaniyu operatsii s ispolzovaniyem paketov Statsstica i Excel. Uchebnoye posobiye, [2-ye izd.] [ Fundamentals of Statistical Analysis. Workshop on statistical methods and operation research using Statsstica and Excel packages. Textbook, [2nd ed.]]. Moscow: «Forum» [in Russian].
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