DETERMINANTS OF SLEEP QUALITY IN PATIENTS WITH OBESITY IN COMBINATION WITH ARTERIAL HYPERTENSION AND IRRITATED BOWEL SYNDROME WITH CONSTIPATIONS
DOI:
https://doi.org/10.11603/1811-2471.2021.v.i4.12810Keywords:
comorbid pathology, arterial hypertension, irritable bowel syndrome with constipation, somnological anamnesis, Epworth sleep scaleAbstract
SUMMARY. Possible pathogenetic, potentially modified risk factors for obesity, hypertension, and irritable bowel syndrome with constipation may include impaired duration and quality of sleep and episodes of sleep apnea. Although the severity and depth of these disorders in the comorbidity of these three diseases have not been studied.
The aim – to study the nature of changes in sleep quality in comorbid patients with obesity, hypertension in combination with irritable bowel syndrome with constipation.
Material and Methods. We examined 52 patients with irritable bowel syndrome with constipation, 18 – with hypertension of II degree, without concomitant pathology with normal body weight and 120 patients with comorbidity of obesity of various degrees in combination with hypertension and irritable bowel syndrome with constipation. To assess the quality of sleep, a somnological history was collected, and patients completed a subjective sleep score evaluation form, the Epworth Sleepiness Scale, and a sleep apnea screening questionnaire.
Results. Analysis of the symptoms of subjective assessment of sleep quality shows a decrease in this indicator in patients with comorbid pathology in 1.9 times compared with healthy, 1.7 times in patients with hypertension and 1.59 times in those examined for irritable bowel syndrome with constipation. The results of the evaluation of the Epworth Sleep Scale show that daytime sleepiness in patients with comorbid pathology was 2.4 times (p<0.01) more common than in patients with hypertension and irritable bowel syndrome with constipation without concomitant pathology. The greatest severity of obstructive sleep apnea syndrome in patients with a combination of obesity, hypertension and irritable bowel syndrome with constipation was 4.3 times more pronounced than in healthy people, and in hypertension - 2.8, while in irritable bowel syndrome with constipation 1.4 times less.
Conclusions. Thus, as can be seen from the data obtained, the lack of quality and duration of night sleep, increasing the number and severity of episodes of sleep apnea are characteristic of patients with irritable bowel syndrome with constipation and hypertension and especially for their combination with obesity. be a potentially modified factor in the progression of comorbid pathology and requires medical correction.
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