SYNTHESIS AND SERUM ALBUMIN FUNCTION DISORDERS IN DIFFERENT PATHOLOGICAL CONDITIONS OF THE BODY
DOI:
https://doi.org/10.11603/1811-2471.2021.v.i3.12504Keywords:
albumin, albumin synthesis and function disorders, hypoalbuminemia, hyperalbuminemiaAbstract
The review highlights the data of the modern literature on pathological changes in the metabolism and function of serum albumin in various diseases and pathological conditions.
The aim – to conduct the analysis of publications on serum albumin dysfunction and their impact on the body, as well as to show the prospects for further research in this area.
Material and Methods. Biblio-systematic and analytical methods were used in the study. A review and analysis of modern literature was carried out in the Medline and PubMed database.
Results. Briefly covered modern understanding of the synthesis and function of human serum albumin, causes a decrease in its concentration in blood plasma, quantitative and qualitative changes in various pathological conditions. Report on the latest literature data on the transport and antioxidant properties of albumin, its structural changes.
Conclusions. The prevalence of albumin in the human body and the diversity of its functions determines the importance of the influence of various pathological processes on its metabolism. The main factors that cause changes in albumin metabolism are diseases that lead to disruption of its formation, increased loss, and redistribution between tissues, as well as structural changes that affect the function of this protein.
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