EFFECT OF ENTEROSGEL AND CARBOLINE (ACTIVATED CARBON) FOOD ADDITIVE ON INTESTINAL MICROFLORA
DOI:
https://doi.org/10.11603/1811-2471.2020.v.i4.11605Keywords:
colon microflora, enterosorbents, Enterosgel, “efferent” methods of treatment, CarbolineAbstract
SUMMARY. Currently, much attention in practical medicine is paid to the so-called “efferent” methods of treatment, which allow you to clean the internal environment and remove foreign substances from the body of a sick person.
The aim – to compare the effect of enterosorbents on the microflora of the large intestine.
Material and Methods. The experiments were performed on Wistar rats with an initial body weight of 200–220 g, which were kept under standard vivarium conditions. Animals were divided into 2 groups (18 males and 18 females – in each of them). I – control group, ІІ – experimental. Group I consisted of intact rats, whose feeding was standard. Group II – rats, which received enterosgel and food supplement Carboline (activated charcoal) during normal feeding.
Results. In the feces of white rats treated with enterosgel for 7 days, the content of bifidobacteria increased by 11 % and lactobacilli by 25 %. Carboline increased the number of lactobacilli and bifidobacteria in the first period of the study (day 7) by 14 %. In the large intestine of animals treated with Enterosgel for 14 days, the content of bifidobacteria increased to (8±0.2) lg CFU / g (26.98 %) and lactobacilli to (7.8±0.3) lg CFU / g (27.86 %).
Conclusions. A study of the microflora of the gastrointestinal tract found that the intake of enterosgel and carboline was accompanied by a slight improvement in the microbiocenosis of the colon, which was manifested by an increase in bifidobacteria and lactobacilli, nonpathogenic Escherichia coli and decreased protein.
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