RELATIONSHIP BETWEEN LEFT VENTRICULAR MYOCARDIAL HYPERTROPHY AND DYSLIPIDEMIA IN CHILDREN AND ADOLESCENTS WITH ARTERIAL HYPERTENSION
DOI:
https://doi.org/10.11603/1811-2471.2020.v.i3.11584Keywords:
arterial hypertension, left ventricular hypertrophy, dyslipidemia, children, adolescentAbstract
Left ventricular hypertrophy (LVH) is an important clinical condition that makes a significant contribution to the development of serious cardiovascular events and is modified by both hemodynamic and non-hemodynamic factors. Epidemiological studies have convincingly proven the existence of a link between lipid metabolism disorders and the development of cardiovascular diseases. In this regard, the early detection of LVH in children and adolescents and the determination of factors affecting its development is important for the prevention of cardiovascular disease in adulthood.
The aim – to determine the relationship between changes in the lipid profile of blood serum in children and adolescents with arterial hypertension (AH) and left ventricular hypertrophy.
Material and Methods. 118 adolescents aged 12–17 years with stable and labile forms of arterial hypertension and prehypertension hospitalized to cardiopulmonary department due to ambulatory single-measured blood pressure elevation were observed.
Results. The high frequency of left ventricular hypertrophy in children and adolescents with hypertension (33.9 %) was established. Two groups of adolescents with hypertension were selected taking into account the presence or absence of LVH. The relationship between the presence of dyslipidemia and left ventricular myocardial hypertrophy was revealed. The presence of dyslipidemia in children with hypertension increases the risk of LVH by 2–4 times, with an increase in the levels of triglycerides and very low density lipoproteins, and a decrease in the level of high density lipoproteins in the blood serum. It is necessary to determine the lipid profile of blood serum in children and adolescents with hypertension and prehypertension.
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