CHRONIC PAIN IN PARKINSON’S DISEASE: RESULTS OF REGIONAL REGISTRY ANALYSIS
DOI:
https://doi.org/10.11603/1811-2471.2020.v.i2.11341Keywords:
Parkinson’s disease, chronic pain, diagnosisAbstract
The aim – was to assess the prevalence of chronic pain in patients with Parkinson's disease (PD) in Odesa region.
Material and Methods. The study was conducted on the basis of the Regional Clinical Hospital (Odesa). A retrospective analysis of the registry of patients (n=527) of PD, created by specialists of the regional center of extrapyramidal pathology. Additionally, a prospective examination of 50 patients aged 50–60 years with a verified diagnosis of PD was carried out. We evaluated the motor and non-motor manifestations of the disease, especially its course, paying particular attention to the manifestations of pain, depending on the therapy used.
Results. The total score for KPPQ flares averaged (26.9±2.0) points. The highest intensity of the pain syndrome was observed for pain associated with fluctuations – (20.5±6.1) points and for night pain – (13.5±2.0) points. With orofascial pain, its intensity was (8.4±3.3) points, and with radicular pain – (7.5±2.7) points. With edema and signs of inflammation, the intensity of the pain responded (9.9±2.4) points. When assessing the effect of treatment on the severity of pain during prospective observation, it was found that the intensity of pain according to VAS decreases after 3 months by 30–35 %.
Conclusions. In 121 (23.0 %) patients, pain syndrome of varying severity occurs. The most common were night pains (21.5 %) and musculoskeletal pains, both isolated (23.1 %) and in various combinations. Pain with fluctuations of various localization occurred in 27 (5.1 % of the total number of persons in the registry (n = 527)). Night pains occurred in 94 (17.8 %) cases, orofascial – in 29 (5.5 %). Pain associated with edema and signs of inflammation were observed in 58 (11.0 %), radicular pain – in 37 (7.0 %). When using combined antiparkinsonian therapy, the intensity of pain according to VAS decreases after 3 months by 30–35 %
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