ANALYSIS OF BONE-METABOLIC CHANGES IN COMORBIDITY OF CHRONIC PANCREATITIS AND CHRONIC GASTRODUODENITIS IN MALES
DOI:
https://doi.org/10.11603/1811-2471.2019.v.i3.10493Keywords:
bone mineral density, chronic gastroduodenitis, chronic pancreatitis, chronic hepatitisAbstract
SUMMARY. In recent years, much attention has been paid to secondary osteoporosis, which occurs on the basis of comorbid pathology, and, as a consequence, in young people
The aim – to study the characteristics of bone minaral in men with comorbid pathology of the digestive system.
Material and Methods. 67 male patients with combined pathology of the gastroduodenopancreatic zone and liver and 20 practically healthy persons were examined. The survey included 17 patients (25.4 %) with chronic gastroduodenitis, 24 (35.8 %) with chronic gastroduodenitis in combination with chronic pancreatitis and 26 (38.8 %) with chronic gastroduodenitis in combination with chronic pancreatitis on the background of chronic hepatitis. Patients' ages ranged from 20 to 73 years, with an average age of (43.54±1.25) years. For quantitative assessment of bone mineral density, a two-photon x-ray densitometer (DEXA) was used for the axial skeleton of Lunar (USA). The incidence of osteoporosis is found to be higher in the groups of patients with combined pathology of digestive organs, in particular in patients with CGD and СP in combination with CH by 4.6 times, in patients with CGD in combination with CP – 2.8 times in comparison with CGD. Depth of osteodeficiency was significantly increased (p <0.05) in patients with comorbid pathology.
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