PECULIARITIES OF STRUCTURAL ORGANIZATION AND BLOODSTREAM OF PAROTID GLANDS OF WHITE RATS IN THE NORM

Abstract

A study of the condition of large salivary glands in norm and in various pathological conditions is devoted to a number of scientific works. However, it should be noted that in the scientific literature, the selected issues are not adequately covered. Despite a number of scientific publications on this problem, many fundamentally important issues of the theory remain unclear.

The aim of the study – to establish the peculiarities of the structural organization of the parotid glands of rats and their organ vessels in the norm, as well as their morphometric characteristics.

Materials and Methods. The study had been conducted on mature white male rats. The following morphological methods of investigation, such as histological examination, morphometric evaluation of parenchyma and intrathoracic vessels components, were used. The area of the epithelial cells of the acini, the outer diameter of the striated ducts, the diameter of their lumen and the area of the epithelial cells of these ducts, as well as the size of the outer and inner diameters of the vessels were morphometrically determined. The assessment of the functional state of the vessels was carried out by deducting the coefficient of the Wagenwoort index (CIW) – the ratio of the area of the middle layer of the arteries to the area of their lumen.

Results and Discussion. As a result of studies for establishing a structural organization of parotid glands of intact rats, morphometric parameters of the structural components of parotid glands, which can form the basis for comparison were established. The area of secretory cells of acini in the parotid glands is (270.90±7.24) μm², the outer diameter of the striated ducts is (34.16±2.34) microns, and the lumen is (11.0±0.28) microns respectively. It was found histologically that the intraorganic arteries of the large salivary glands are the arteries of the muscular type and have a structure characteristics of these vessels. The veins have a structure that is also specific for the veins in which muscular elements are poorly developed. The evaluation of the functional state of the vessels was carried out by deducting the coefficient of vascular capacity by the coefficient of Wagenvoort index (CIW). The coefficient of the Wagenvoort index in the small arteries of parotid glands is (184.40±6.57), in the middle vessels – (142.54±4.85) respectively.

Conclusions. As a result of the conducted studies using histological and morphometrical methods we established that the parenchyma’s components of parotid glands of intact rats don’t have the specific features of structural organization. Morphometric parame­ters of the parenchyma’s structural components and intraorgan arteries, which can form the basis for comparison were established.