QUANTITATIVE MORPHOLOGY OF HYPERTROPHIC CARDIOMYOPATHY
DOI:
https://doi.org/10.11603/2415-8798.2017.4.8169Keywords:
hypertrophic сardiomyopathy, morphometry.Abstract
Morphometry is the most appropriate method to study hyperfunctioning and hypertrophied heart, since it allows quantitatively evaluating the processes and phenomena that take place in the heart chambers and interpreting them in sufficient and logical manner.
The aim of the study – to educate morphologists about advantages of using morphometry as the means for appropriate and complete assessment of hyperfunctioning and hypertrophied heart.
Materials and Methods. The study reviews published research on the utility of morphometric methods for assessing the state of both intact and damaged heart.
Results and Discussion. The study assesses current cardiometric methods ranging from macromorphometric to histo- and stereological at the cellular level. These methods allow identifying hypertrophy and atrotophy of the myocardium, and determine salient characteristics pointing to complications in the damaged myocardium.
Conclusions. Morphometric methods were not used researchers to evaluate the changes in hyperfunctioning heart at all levels of the structural organization. There are no accepted informative diagnostic quantitative criteria for compensated and decompensated heart.
References
Avtandilov, G.G. (2002). Osnovy kolichestvennoy patologicheskoy anatomii [Fundamentals of quantitative pathological anatomy]. Moskva : Meditsina, 240 [in Russian].
Babanin, A.A. (2008). Pokazateli razdelnoho vzveshivaniya chastey serdtsa krys pri kombinirovannom vozdeystvii khlor- i fosfororganicheskikh pestitsidov na fone razlichnykh urovney fizicheskoy nagruzki [Indicators of separate weighing of parts of the heart of rats with combined action of chlorine and organophosphorus pesticides against the background of different levels of physical activity]. Tavricheskiy mediko-biologicheskiy vestnik – Taurian medical and biological bulletin, (11), 3 (ch. 1), 14-17 [in Russian].
Bodnar, Ya.Ya. & Trach-Rosolovska, S.V. (2001). Morfometrychni pokaznyky miokarda livogo shlunochka shchuriv riznogo viku pry eksperymentalnomu tsukrovomu diabeti [Morfometricheskie pokazniki miokarda lіvogo shlunochka schuriv riznogo vyku at the experimental tsukrovomu diabeti]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of clinical and experimental medicine, 1 (14), 28-33 [in Ukrainian].
Hnatyuk, M.S., Tatarchuk, L.V. & Yasinovskyi, O.B. (2010). Sekretorna aktyvnist kardiomiotsytiv peredserd pry lehenevomu sertsi [Secretory Activity of Atrial Cardiomyocytes in the Pulmonary Heart]. Halytskyi likarskyi visnyk – Galician Medicinal Journal, 2, 46-48 [in Ukrainian].
Hnatyuk, M.S., Tatarchuk, L.V. & Pryshlyak, A.M. (2010). Vikovi osoblyvosti zmin yaderno-tsytoplazmatychnykh vidnoshen v kardiomiotsytakh chastyn sertsya doslidnykh tvaryn [Age characteristics of changes in nuclear-cytoplasmic relations in cardiomyocytes of the heart parts of experimental animals]. Tavricheskiy mediko-biologicheskiy vestnik – Taurian medical and biological bulletin, 4 (52), 29-32 [in Russian].
Hnatyuk, M.S. & Slabyy, O.B. (2016). Morfometrychna otsinka osoblyvostey remodelyuvannya kamer sertsya z riznymy typamy krovopostachannya [Morphometric evaluation of the features of remodeling of heart cells with different types of blood supply]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of clinical and experimental medicine, 1, 17-20 [in Ukrainian].
Yesipova, I.K. Alisiyevich, V.I. & Purdyayev, Yu.S. (1981). Metod srochnoy differentsialnoy diagnostiki razlichnykh form gipertenzii malogo kruga krovoobrashcheniya u sektsionnogo stola [The method of urgent differential diagnosis of various forms of hypertension of the small circle of blood circulation in the sectional table]. Sud.med.ekspert – Sud.med.expert, (24), 4, 27-30 [in Russian].
Nepomnyashchikh, L.M., Lushnikova, Ye.L. & Nepomnyashchikh, G.I. (2006). Morfometriya i stereologiya gipertrofii serdtsa [Morphometry and stereology of heart hypertrophy]. Novisibirsk : Nauka, 304 [in Russian].
Svishchev, A.V. (1991). Vnutriserdechnyye obyemnyye parametry pri khronicheskoy serdechno-sosudistoy nedostatochnosti po materiyam autopsiy [Intracardiac volume parameters for chronic cardiovascular failure in autopsy]. Arkh. patologii – Arch. pathology, (43), 9, 30-35 [in Russian].
Slabyy, O.B. & Hnatyuk, M.S. (2015). Osoblyvosti strukturnykh zmin anhioarkhitektoniky mikrohemotsyrkulyatornoho rusla shlunochkiv sertsya pry postrezektsiyniy leheneviy arterialniy hipertenziyi [Features of structural changes of angioarchitectonics of the microhemocirculatory channel of the ventricles of the heart at post-injection lung arterial hypertension]. Visnyk naukovykh doslidzhen – Bulletin of scientific researches, 4, 93-95 [in Ukrainian].
Tatarchuk, L.V. (2010). Morfometrychnyi analiz remodelyuvannia kamer sertsia pislia pulmonektomii [Morphometric analysis of remodeling of heart cells after pulmonectomy]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of clinical and experimental medicine, 2, 123-126 [in Ukrainian].
Lorenz, M.W., Von Kegler, S. & Steinmetz, H. (2006). Carotid intima-media thickening indicates a higher vascular risk across a vide age range: prospective data from the carotid atherosclerosis study. Stroke, (37), 1, 87-92.
Lunkenheimera, P.P., Redmanna, K. & Andersonb, R.H. (2005). The architecture of the ventricular mass and its functional implications for organ-preserving surgery. Eur. J. Cardiolothorac. Surg., 27, 183-190.
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