MORPHOLOGICAL CHANGES OF INTERNAL ORGANS IN ANIMALS OF DIFFERENT SEXES WITH CHRONIC STRESS

Authors

  • I. R. Mits I.Ya. Horbachevsky Ternopil State Medical University
  • O. V. Denefil I.Ya. Horbachevsky Ternopil State Medical University
  • O. P. Andriishyn I.Ya. Horbachevsky Ternopil State Medical University

DOI:

https://doi.org/10.11603/2415-8798.2016.3.6994

Keywords:

chronic stress, rats, heart, endocrine glands, morphological changes.

Abstract

It was investigated the effects of chronic prenatal, postnatal and combined stress on the endocrine glands morphological structure changes of young both sexes rats. There were discovered violations of morphological structure of the thyroid gland, which was most in animals with combined stress. In the adrenal glands most changes were observed in rats-males with chronic postnatal and combined stress compared to rats-females. Damage was greatest in all animals with combined stress: increased activity of zona glomerulosa and decreased in zona fasciculata. In the thymus major changes were in rats-males with prenatal, in rats-females – with combined stress. In genitals were major histological changes in rats of both sexes with combined stress. Detected changes indicate the possible development of chronic inflammation, secondary immunodeficiency.

References

Abramov A. V. Sostoyaniye tolerantnosti k glyukoze u samtsov, perenesshikh khronicheskiy prenatal'nyy stress / A. V. Abramov, YU. M. Kolesnik, M. A. Tikhonovskaya // Zaporozhskiy meditsinskiy zhurnal. – 2004. – № 6. – S. 38–41.

Volkova O. V. Osnovy gistologii s gistologicheskoy tekhnikoy / O. V. Volkova, YU. K. Yeletskiy. – M. : Meditsina, 1982. – 304 s.

Pat. na korisnu model' № 99821 UA MPK: G09B 23/28 Sposíb modelyuvannya khroníchnogo ímmobílízatsíynogo stresu, pídsilenogo díêyu gostrogo stresu. Denefíl' O. V., Míts Í. R. – № u201414143; Zyavl. 29.12.2014; Opubl. 25.06.2015. Byul. № 12.

Chronic stress induces ageing-associated degeneration in rat Leydig cells / F. F. Wang, Q. Wang, Y. Chen [et al.] // Asian J. Androl. – 2012. – Vol. 14(4). – P. 643–648.

Clark L. S. Morphological changes in the Atlantic bottlenose dolphin (Tursiops truncatus) adrenal gland associated with chronic stress / L. S. Clark, D. F. Cowan, D. C. Pfeiffer // J. Comp. Pathol. – 2006. – Vol. 135(4). – P. 208–216.

Morphological changes of adrenal gland and heart tissue after varying duration of noise exposure in adult rat / N. Gannouni, A. Mhamdi, M. El May [et al.] // Noise Health. – 2014. – Vol. 16(73). – Р. 416–421.

Parswani M. J. Mindfulness-based stress reduction program in coronary heart disease: A randomized control trial / M. J. Parswani, M. P. Sharma, S. Iyengar // Int. J. Yoga. – 2013. – Vol. 6(2). – P. 111–117.

Physiological responses to emotional excitement in healthy subjects and patients with coronary artery disease / O. P. Piira, J. A. Miettinen, A. J. Hautala [et al.] / Auton. Neurosci. – 2013. – Vol. 177(2). – P. 280–285.

Sex-specific effects of prenatal stress on glucose homoeostasis and peripheral metabolism in rats / P. J. Brunton, K. M. Sullivan, D. Kerrigan [et al.] // J. Endocrinol. – 2013. – Vol. 217 (2). – P. 161–173.

Sex-specific interaction effects of age, occupational status, and workplace stress on psychiatric symptoms and allostatic load among healthy Montreal workers / R. P. Juster, D. S. Moskowitz, J. Lavoie, B. D'Antono / Stress. – 2013. – Vol. 16(6). – P. 616–629.

The relationship of chronic and momentary work stress to cardiac reactivity in female managers: feasibility of a smart phone-assisted assessment system / M. A. Lumley, W. Shi, C. Wiholm [et al.] // Psychosom. Med. – 2014. – Vol. 76 (7). – P. 512–518.

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Published

2016-11-23

How to Cite

Mits, I. R., Denefil, O. V., & Andriishyn, O. P. (2016). MORPHOLOGICAL CHANGES OF INTERNAL ORGANS IN ANIMALS OF DIFFERENT SEXES WITH CHRONIC STRESS. Bulletin of Scientific Research, (3). https://doi.org/10.11603/2415-8798.2016.3.6994

Issue

No. 3 (2016)

Section

EXPERIMENTAL RESEARCH

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