MORPHOLOGICAL CHANGES IN THE GENITALS MATURE FEMALE WHITE RATS UNDER THE EXPERIMENTAL CHRONIC TOXIC HEPATITIS

Authors

  • L. Ye. Lymar I.Ya. Horbachevsky Ternopil State Medical University
  • N. A. Lymar I.Ya. Horbachevsky Ternopil State Medical University

DOI:

https://doi.org/10.11603/2415-8798.2016.3.6992

Keywords:

morphological changes, uterus, ovaries, chronic toxic hepatitis, reproductive function.

Abstract

Saving reproductive health as an important lever suspension depopulation processes and improve the demographic situation in Ukraine is a priority in the health and development of medical science. The main reason for the negative demographic trends is the high level of sterility. The reason of infertility status in 15-25 % is hormonal change [1]. The problem of reproductive dysfunction is one of the leading places among gynecological diseases and continues to be relevant, since it leads to disability and reduced reproductive function. A large role in causing this problem belongs not only genetically determined disorder, comorbidity but also the body. Women have often a combination reproductive system dysfunction with chronic hepatitis different genesis. This prompted us to conduct experimental work with the aim of detailed study and analysis of this problem. In the study available to the sources of literature we found similar modeling of experimental studies on structural changes in the reproductive system in chronic hepatitis.We modeled chronic toxic hepatitis in mature female white rats. We studied the results of the clinical, histological studies, indicators of immune and hormonal status, liver function in experimental animals and their reproductive function under the experimental toxic hepatitis. The study involved 40 sexually mature females of white rats that simulated chronic toxic hepatitis (CTH). Were studied the clinical manifestations of the disease, the condition of liver function and morphological changes in the reproductive organs of these animals and their reproductive function.

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Published

2016-11-23

How to Cite

Lymar, L. Y., & Lymar, N. A. (2016). MORPHOLOGICAL CHANGES IN THE GENITALS MATURE FEMALE WHITE RATS UNDER THE EXPERIMENTAL CHRONIC TOXIC HEPATITIS. Bulletin of Scientific Research, (3). https://doi.org/10.11603/2415-8798.2016.3.6992

Issue

No. 3 (2016)

Section

EXPERIMENTAL RESEARCH

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