TOXIC EFFECTS OF MANGANESE
DOI:
https://doi.org/10.11603/2415-8798.2016.3.6956Keywords:
manganese, toxicity, manganism, neurodegenerative disorders, idiopathic Parkinson's disease.Abstract
Manganese is a vital trace element, that is necessary for blood formation and correct functioning of the brain, hormonal and reproductive system, genetic apparatus and antioxidant system of cells. this article analyzes the data of scientific publications and online resources relating to current issues of molecular biology, medicine, physiology and toxicology of manganese. the problem of high doses of manganese exposure to the human body was highlighted. the negative effects that occur in the body in the excess of manganese was described.References
Beslekoyeva E. D. Biologicheskaya rol' soyedineniy margantsa / E. D. Beslekoyeva, O. V. Neyelova // Uspekhi sovremennogo yestestvoznaniya. – 2011. – № 8. – s. 222.
Domanova A. A. Bíologíchna rol' margantsyu v organízmí lyudini í tvarin : kursova robota / A. A. Domanova // Chernígívs'kiy derzhavniy pedagogíchniy uníversitet ímení T. G. Shevchenka, kafedra botaníki, zoologíí̈ ta okhoroni prirodi. – Chernígív, 2008.
Mazurina D. l. Negativnyye effekty margantsa pri khronicheskom postuplenii v organizm s pit'yevoy vodoy / D. l. Mazurina // Ekologiya cheloveka. – 2015. – № 3. – s.25–31.
Mazurina D. l. Otsenka balansa neyromediatorov tsentral'noy nervnoy sistemy u detey s povyshennym soderzhaniyem margantsa v krovi / D. l. Mazurina // Vestnik Permskogo universiteta. – 2014. – № 3. – s. 39–42.
Tmenova a. O. biologicheskaya rol' margantsa i yego soyedineniy / A. O. Tmenova, l. M. Kubalova // sovremennyye naukoyemkiye tekhnologii. – 2014. – № 7–2. – s. 92.
Vliyaniye margantsa na kostnyy metabolizm u detey, prozhivayushchikh v usloviyakh vozdeystviya khimicheskikh faktorov sredy obita- niya / O. YU. Ustinova, N. V. Zaytseva, i. a. Permyakov [i dr.] // Fundamental'nyye issledovaniya. – 2011. – № 9 – s. 314–317.
Aschner J. Nutritional aspects of manganese homeostasis / J. Aschner, M. Aschner // Mol. Aspects Med. – 2005– Vol. 26 – P. 353–362.
Aschner M. Manganese dosimetry: species differences and implications for neurotoxicity / M. Aschner, K. Erikson, D. Dorman // Crit. Review Toxicol. – 2005 – Vol. 35 – P. 1–32.
Auffan M. Chemical stability of metallic nanoparticles: A parameter controlling their potential cellular toxicity in vitro / M. Auffan, J. Rose, M. R. Wiesner, J.-Y. Bottero // Environmental Pollution – 2009 – Vo l. 157 – P. 1127–1133.
Babadi V. Y. The Toxic Effect of Manganese on the Acetylcholinesterase Activity in Rat Brains / [V. Y. Babadi, L. Sadeghi, K. Shirani [et al.]] // Journal of Toxicology. – 2014. – Vol. 2014.
Beacha R. S. Zinc, Copper, and Manganese in immune function and experimental oncogenesis / R. S. Beacha, M. E. Gershwina, L. S. Hurleya // Nutrition and Cancer – 2006 – Vol. 3, Issue 3 – P. 172–191.
Blecharz-Klin K. Effect of intranasal manganese administration on neurotransmission and spatial learning in rats / K. Blecharz-Klin, A. Piechal, I. Joniec-Maciejak [et al.] // Toxicology and Applied. Pharmacology. – 2012. – Vol. 265 – №.1 – P. 1–9.
Manganese cumulative exposure and symptoms: a follow-up study of alloy workers / M. Bouchard, D. Mergler, M. Baldwin, M. Panisset // NeuroToxicology – 2008 – Vol. 29(4) – P. 577–583.
Bowler R. M. Dose-effect relations between manganese exposure and neurological, neuropsychological and pulmonary function in confined space bridge welders / [R. M. Bowler, H. A. Roels, S. Nakagawa [et al.] // Occup. Environ. Med. – 2007 – Vol. 64 – P. 167–177.
Bowler R. M. Environmental exposure to manganese in air: Associations with tremor and motor function / R. M. Bowler, C. L. Beseler, V. V. Gocheva // Sci. Total. Environ. – 2015 – № 541. – P. 646–654.
Role of manganese in neurodegenerative diseases: invited review / A. B. Bowman, G. F. Kwakye, E. H. Hernández, M. Aschner // Journal of Trace Elements in Medicine and Biology – 2011 – Vol. 25 –P. 191–203.
Calne D. B. Manganism and idiopathic parkinsonism: similarities and differences / D. B. Calne, N. S. Chu, C. C. Huang [et al.] // Neurology – 1995 – Vol. 44 – P.1583–1586.
Cersosimo M. G. The diagnosis of manganese-induced parkinsonism / M. G. Cersosimo, W. C. Koller // Neurotoxicology – 2006 – Vol. 27 – P. 340–346.
Crossgrove J. Manganese toxicity upon overexposure / J. Crossgrove, W. Zheng // NMR in Biomedicine. – 2005 – Vol. 17 – № 8. – P. 544–553.
Deskin R. The effect of chronic manganese administration on some neurochemical and physiological variables in neonatal rats / R. Deskin, S. Bursian, F. Edens // Gen. Pharmacol. – 2005. – Vol. 12. – P. 279–280.
Dobson A.W. Manganese neurotoxicity / A. W. Dobson, K. M. Erikson, M. Aschner // Ann. NY Acad. Sci. – 2004 – Vol. 1012. – P. 115–128.
Manganese neurotoxicity: a focus on the neonate / K. M. Erikson, K. Thompson, J. Aschner, M. Aschner // Pharmacology and Therapeutics – 2007. – Vol. 113 – № 2 – P. 369–377.
Gavin C. E. Manganese and calcium transport in mitochondria: implications for manganese toxicity / C. E. Gavin, K. K. Gunter, T. E. Gunter // Neurotoxicology. – 1999. – Vol. 20 – P. 445–453.
Speciation of manganese in cells and mitochondria: a search for the proximal cause of manganese neurotoxicity / T. Gunter, C. Gavin, M. Aschner, K. Gunter // NeuroToxicology. – 2006. – Vol. 27(5) – P. 765–776.
Guyton A. Textbook of medical physiology / A. Guyton, J. Hall // Philadelphia: W. B. Saunders Company. – 1996. – P. 72.
Hamai D. Oxidative basis of manganese neurotoxicity / D. Hamai, S. Bondy // Ann. N Y Acad. Sci. – 2004. – Vol. 1012. – P. 129–141.
Huang Y. L. In vitro effects of metal ions (Fe2+, Mn2+, Pb2+) on sperm motility and lipid peroxidation in human semen / Y. L. Huang, W. C. Tseng, T. H. Lin // J. Toxicol. Environ. Health – 2001 – Vol. 62 – P. 259–267.
Downloads
Published
How to Cite
Issue
Section
License
Authors who sent their manuscript to "Вісник наукових досліджень. Bulletin of Scientific Research" Surgery agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)