РОЗВИТОК МОЛЕКУЛЯРНОЇ ГЕНЕТИКИ В СПОРТІ: ПРОГНОЗИ І ПЕРСПЕКТИВИ
DOI:
https://doi.org/10.11603/2415-8798.2015.2.5567Abstract
У статті розглянуто питання впливу розвитку молекулярної генетики на професійні досягнення спортсменів. З одного боку, безумовно, визначення генів, які відповідають за певні фізичні якості майбутнього спортсмена, дозволяє провести ранній і своєчасний відбір. Така тактика призведе до гарантовано високих результатів у майбутньому. Але, з іншого боку, молекулярна генетика може стимулювати штучне підвищення фізичних якостей за рахунок генного допінгу, що вкрай небажано для здоров’я спортсмена.
References
Astratenkova I. V. Otsenka summarnogo vklada alleley genov v opredeleniye predraspolozhennosti k sportu / I. V. Astratenkova // Teoriya i praktika fizicheskoy kul'tury. – 2008. – № 3. – S. 67–72.
Akhmetov I. I. Ispol'zovaniye DNK-tekhnologiy dlya realizatsii kontseptsii sportivno–oriyentirovannogo fizicheskogo vospitaniya uchashchikhsya shkol / I. I. Akhmetov, I. V. Astratenkova, A. I. Komkova // Naberezhnyye Chelny : Fizicheskaya kul'tura: vospitaniye, obrazovaniye, trenirovka. – 2006. – № 1. – S. 28–31.
Akhmetov I. I. Molekulyarnaya genetika sporta : monografiya / I. I. Akhmetov. – M. : Sovetskiy sport, 2009. – 268 s.
Vyal'shin I. T. Informativnost' morfologicheskikh pokazateley sportivnoy perspektivnosti bokserov na etape sportivnogo sovershenstvovaniya : avtoref. dis. na soiskaniye nauchn. stepeni kand. ped. nauk: 13.00.04; 14.03.01 / I. T. Vyal'shin. – Malakhovka, 2010. – 26 s.
Dyatlov D. A. Dostizheniya sovremennoy sportivnoy genetiki / D. A. Dyatlov // Teoriya i praktika fizicheskoy kul'tury. – 2008. – № 4. – S. 3–5.
Mosse I. B. Genetika sporta: vchera, segodnya, zavtra / I. B. Mosse // Trudy BGU. – 2012. – № 7. – S. 56–68.
Mosse I. B. Geneticheskiye markery ustoychivosti organizma k gipoksii / I. B. Mosse // Molekulyarnaya i prikladnaya genetika. – 2010. – T. 11. – S. 74–82.
Barton-Davis E.R. Viral mediated expression of insulin-like growth factor 1 blocks the aging-related loss of skeletal muscle function / E. R. Barton-Davis // PNAS USA. – 1998. – Vol. 5. – P. 15603–15607.
Beiter T. Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping / T. Beiter // Exerc Immunol Rev. – 2008. – Vol. 14. – Р. 73–85.
Bouchard, C. Genetic and molecular aspects of sport performance / C. Bouchard, E. Hoffman. – UK: Blackwell Publishing, 2011. – 404 р.
Lee S. J. Regulation of myostatin activity and muscle growth / S. J. Lee, A. C. McPherron, // PNAS USA. – 2001. – Vol. 98. – Р. 9306–9311.
Losordo D.W. Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia / D.W. Losordo // Circulation. – 2002. – Vol. 105. – Р. 2012–2018.
Lundby C. Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions / C. Lundby, M. Gassmann, H. Pilegaard // Eur. J. Appl. Physiol. – 2006 – Vol. 96. – P. 363–369.
Schjerling P. Gene doping / P. Schjerling // Scand. J. Med. Sci. Sports. – 2008. – Vol. 18. – P. 121–122.
Stepto N. K. Global gene expression in skeletal muscle from well-trained strength and endurance athletes / N. K. Stepto // Med. Sci. Sports Exerc. – 2009. – Vol. 41. – P. 546–565.
Yan Jie Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle / Jie Yan // Cell Metabolism. – 2012. – Vol. 15. – P. 405–411.
Ye X. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer / X. Ye // Science. – 1999. – Vol. 283. – P. 88–91.
Zhou S.Adeno-associated virus mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primates / S. Zhou // Gene Therapy. – 1998. – Vol. 5. – P. 665–670.
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