ISSUES OF ANTIRETROVIRAI THERAPY IN HIV-INFECTED PATIENTS
DOI:
https://doi.org/10.11603/1681-2786.2017.3.8162Keywords:
HIV, ART, CD4 T-lymphocytes, opportunistic infections.Abstract
Research objective based on observations of CHOGORDS of HIV patients over 5 years (2010-2015), which was assigned to ART, to assess the effectiveness of designated schemes and identify additional factors and deficiencies that may affect the results of the ART.
Materials and methods observations under our supervision in Dnipropetrovsk region AIDS Centre was 450 patients who was appointed ART in 2010. Surveillance conducted over 5 years.
Results and discussion. The analysis on the basis of observation and monitoring 450 patients for HIV in Dnipropetrovsk region AIDS Centre, which has been assigned to antiretroviral therapy (art) in 2010 year over 5 years. Identified additional factors and deficiencies that might affect the results ART.
Conclusions. Majority patients beginning therapy up to 5 years of diagnosis of HIV infection, of which 51% in stage of AIDS, indicating that certain weaknesses in identifying patients for HIV infection at the early stages of the disease, which can lead to progression of disease and mortality from opportunistic diseases and AIDS.
References
Belyaeva V.V., Kravchenko A.V. (2010). Belyaeva V.V., Kravchenko A.V. (2010). Priverzhennost vysokoaktivnoj protivovirusnoj terapii pri VICH-infekcii [Adherence to highly active antiviral therapy in HIV infection]. SHAGI professional – STEPS professional, 6, 12-21 [in Russian].
Goujard, C., Girault, I., Rouzioux, C., Lécuroux, C., Deveau, C., Chaix, M. L., ... & Meyer, L. (2012). HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy. Antiviral therapy, 17(6), 1001-1009.
Kravchenko A.V., Kanestr V.G., Gankina N.U. (2010). Usilennye ritonavirom ingibitory proteaz VICH v sostave skhem pervoj linii antiretrovirusnoj terapii [Ritonavir-boosted HIV protease inhibitors as part of first-line antiretroviral therapy regimens]. Epidemiologiya i infekcionnye bolezni – Epidemiology and infectious diseases, 3, 22-27 [in Russian].
Nakaz MOZ Ukrayiny № 551 vіd 12.07.2010 r. «Pro zatverdzhennya klіnіchnogo protokolu antiretrovіrusnoy terapіy VІL-іnfekcіy u doroslih ta pіdlіtkіv». [Order of The Ministry of Health of Ukraine dated July No 551 of 12.07.2010. «About the solidification of the clinical protocol of antiretroviral therapy VIL-infectious diseases in the elderly and piedmata.»] [in Ukrainian].
Pokrovskaya A.V.(2010). Faktory, vliyayushchie na techenie VICH–infekcii [Factors influencing the course of HIV infection]. Ehpidemiologiya i infekcionnye bolezni – Epidemiology and infectious diseases, 3, 60-63 [in Russian].
Shostakovych-Koretska L.R, Shevelova O.V, Shevchenko O.P. (2016). Vizhivannya priznachenih pervinnih skhem antiretrovіrusnoy terapіy u hvorih na VІL-іnfekcіyu [Survival of prescribed primary antiretroviral therapy schemes in patients with HIV]. VІL іnfekcіya ta tuberkuloz – HIV infection and tuberculosis, 1, 43-46 [in Ukrainian].
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